Glaucoma

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Genetics October 2017

A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma

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Mohsen Ghanbari; Adriana I. Iglesias; Henriët Springelkamp; Cornelia M. van Duijn; M. Arfan Ikram; Abbas Dehghan; Stefan J. Erkeland; Caroline C. W. Klaver; Magda A. Meester-Smoor; for the International Glaucoma Genetics Consortium (IGGC)
TAGS: glaucoma, open-angle glaucoma, genetics, endophenotype, micro rna
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5368-5377. doi: 10.1167/iovs.17-22410

Includes: Supplemental Content

Glaucoma October 2017

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

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Kate E. Keller; John M. Bradley; Ying Ying Sun; Yong-Feng Yang; Ted S. Acott
TAGS: actins, mitochondria, cd44 antigens, cellular structures, dimethyl sulfoxide, microscopy, confocal, software, body tissue, trabecular meshwork, diagnostic imaging, vesicle, homing-associated cell adhesion molecule, transfer technique
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5298-5307. doi: 10.1167/iovs.17-22732

Includes: Supplemental Content

Glaucoma October 2017

Clinical and Biological Evaluations of Biodegradable Collagen Matrices for Glaucoma Drainage Device Implantation

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Minjung Song; Seunghyun Lee; Deokyeong Choe; Sera Kim; Young Hoon Roh; Seungsoo Rho
TAGS: collagen, glaucoma drainage implants, postoperative care, surgical procedures, operative, intraocular pressure, morphology, implantation procedure, catabolism, language morphology
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5329-5335. doi: 10.1167/iovs.17-22579

Glaucoma October 2017

Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult

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Andrew P. Voorhees; Ning-Jiun Jan; Morgan E. Austin; John G. Flanagan; Jeremy M. Sivak; Richard A. Bilonick; Ian A. Sigal
TAGS: nerve tissue, intraocular pressure, stress, cribriform plate, shape
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5336-5346. doi: 10.1167/iovs.17-22015

Glaucoma October 2017

Myocilin Regulates Metalloprotease 2 Activity Through Interaction With TIMP3

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Myung Kuk Joe; Raquel L. Lieberman; Naoki Nakaya; Stanislav I. Tomarev
TAGS: eye, proteins, metalloproteases, myoc gene
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5308-5318. doi: 10.1167/iovs.16-20336

Glaucoma October 2017

Patients With Normal Tension Glaucoma Have Relative Sparing of the Relative Afferent Pupillary Defect Compared to Those With Open Angle Glaucoma and Elevated Intraocular Pressure

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Mitchell Lawlor; Ana Quartilho; Catey Bunce; Neil Nathwani; Emily Dowse; Debbie Kamal; Gus Gazzard
TAGS: glaucoma, raised intraocular pressure, pathophysiology, relative afferent pupillary defect, pupil, open-angle glaucoma, glaucoma, normal-tension
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5237-5241. doi: 10.1167/iovs.17-21688

Multidisciplinary Ophthalmic Imaging October 2017

Comparison of Sectoral Structure-Function Relationships in Glaucoma: Vessel Density Versus Thickness in the Peripapillary Retinal Nerve Fiber Layer

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Kimikazu Sakaguchi; Tomomi Higashide; Sachiko Udagawa; Shinji Ohkubo; Kazuhisa Sugiyama
TAGS: glaucoma, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5251-5262. doi: 10.1167/iovs.17-21955

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging October 2017

Wide-Field OCT Angiography Investigation of the Relationship Between Radial Peripapillary Capillary Plexus Density and Nerve Fiber Layer Thickness

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Yali Jia; Joseph M. Simonett; Jie Wang; Xiaohui Hua; Liang Liu; Thomas S. Hwang; David Huang
TAGS: angiogram, nerve fibers, blood capillaries, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5188-5194. doi: 10.1167/iovs.17-22593

Glaucoma October 2017

Intraday Repeatability of Bruch's Membrane Opening-Based Neuroretinal Rim Measurements

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Philip Enders; Andreas Bremen; Friederike Schaub; Manuel M. Hermann; Michael Diestelhorst; Thomas Dietlein; Claus Cursiefen; Ludwig M. Heindl
TAGS: magnetic resonance angiography, glaucoma, bruch's basal membrane, optic disk, retinal nerve fiber layer, mineralocorticoid receptor antagonists, neuroretinal rim, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5195-5200. doi: 10.1167/iovs.17-22812

Glaucoma October 2017

Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma

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Sushma Verma; Monisha E. Nongpiur; Hnin H. Oo; Eray Atalay; David Goh; Tina T. Wong; Shamira A. Perera; Tin Aung
TAGS: angle closure glaucoma, plateau iris, optical coherence tomography, ultrasound biomicroscopy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5093-5097. doi: 10.1167/iovs.17-22364

Glaucoma October 2017

Hydrogen Sulfide Protects Retinal Ganglion Cells Against Glaucomatous Injury In Vitro and In Vivo

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Hanhan Liu; Fabian Anders; Solon Thanos; Carolina Mann; Aiwei Liu; Franz H. Grus; Norbert Pfeiffer; Verena Prokosch-Willing
TAGS: oxidative stress, glaucoma, hydrostatic pressure, mechlorethamine, reperfusion injury, retinal ganglion cells, wounds and injuries, hydrogen sulfide, intraocular pressure, raised intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5129-5141. doi: 10.1167/iovs.17-22200

Glaucoma October 2017

Effect of Body Position on Epsicleral Venous Pressure in Healthy Subjects

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Nitika Arora; Jay W. McLaren; David O. Hodge; Arthur J. Sit
TAGS: venous pressure level, eye, intraocular pressure, posture, sitting position
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5151-5156. doi: 10.1167/iovs.17-22154

Retina October 2017

Effect of Circulating Omentin-1 on the Retinal Circulation in Patients With Type 2 Diabetes Mellitus

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Tsuneaki Omae; Taiji Nagaoka; Akitoshi Yoshida
TAGS: diabetes mellitus, type 2, retina circulation, vascular flow
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5086-5092. doi: 10.1167/iovs.17-22030

Retina October 2017

Changes in Choroidal Blood Flow and Morphology in Response to Increase in Intraocular Pressure

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Tomohiko Akahori; Takeshi Iwase; Kentaro Yamamoto; Eimei Ra; Hiroko Terasaki
TAGS: vascular flow, choroid, intraocular pressure, morphology, language morphology
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5076-5085. doi: 10.1167/iovs.17-21745

Glaucoma October 2017

Impact of Myopia on Corneal Biomechanics in Glaucoma and Nonglaucoma Patients

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Sunee Chansangpetch; Rawiphan Panpruk; Anita Manassakorn; Visanee Tantisevi; Prin Rojanapongpun; Cameron P. Hurst; Shan C. Lin
TAGS: glaucoma, biomechanics, open-angle glaucoma, myopia, cornea, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4990-4996. doi: 10.1167/iovs.17-22219

Includes: Supplemental Content

Glaucoma October 2017

Progressive Deformation of the Optic Nerve Head and Peripapillary Structures by Graded Horizontal Duction

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Soh Youn Suh; Alan Le; Andrew Shin; Joseph Park; Joseph L. Demer
TAGS: optic disk, gaze, displacements, abduction, adduction
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5015-5021. doi: 10.1167/iovs.17-22596

Retina October 2017

Effects of Intravitreal Dexamethasone Implants on Retinal Oxygen Saturation, Vessel Diameter, and Retrobulbar Blood Flow Velocity in ME Secondary to RVO

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Katharina Eibenberger; Leopold Schmetterer; Sandra Rezar-Dreindl; Piotr Wozniak; Reinhard Told; Georgios Mylonas; Christoph Krall; Ursula Schmidt-Erfurth; Stefan Sacu
TAGS: oxygen, alveolar ventilation function, dexamethasone, blood flow velocity, retinal vessels, cell respiration, oxygen saturation measurement, implants, diameter
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5022-5029. doi: 10.1167/iovs.17-22229

Glaucoma September 2017

Genetic Deletion of the NOS3 Gene in CAV1 −/− Mice Restores Aqueous Humor Outflow Function

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Maomao Song; Jihong Wu; Yuan Lei; Xinghuai Sun
TAGS: genes, aqueous humor, eye, genetics, intraocular pressure, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4976-4987. doi: 10.1167/iovs.16-21072

Includes: Supplemental Content

Letters to the Editor September 2017

Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

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Xinying Li; Jiawei Wang
TAGS: polymerase chain reaction, open-angle glaucoma, pilot projects, aqueous humor, micro rna
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4988-4988. doi: 10.1167/iovs.17-22568

Letters to the Editor September 2017

Author Response: Comparison of MicroRNA Expression in Aqueous Humour of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

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Hari Jayaram; Diana C. Lozano; Elaine C. Johnson; Tiffany E. Choe; William O. Cepurna; Julie A. Saugstad; John C. Morrison; Kate E. Keller
TAGS: polymerase chain reaction, open-angle glaucoma, pilot projects, aqueous humor, micro rna
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4989-4989. doi: 10.1167/iovs.17-22866

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A Genome-Wide Scan for MicroRNA-Related Genetic Variants Associated With Primary Open-Angle Glaucoma

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

Clinical and Biological Evaluations of Biodegradable Collagen Matrices for Glaucoma Drainage Device Implantation

Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult

Myocilin Regulates Metalloprotease 2 Activity Through Interaction With TIMP3

Patients With Normal Tension Glaucoma Have Relative Sparing of the Relative Afferent Pupillary Defect Compared to Those With Open Angle Glaucoma and Elevated Intraocular Pressure

Comparison of Sectoral Structure-Function Relationships in Glaucoma: Vessel Density Versus Thickness in the Peripapillary Retinal Nerve Fiber Layer

Wide-Field OCT Angiography Investigation of the Relationship Between Radial Peripapillary Capillary Plexus Density and Nerve Fiber Layer Thickness

Intraday Repeatability of Bruch's Membrane Opening-Based Neuroretinal Rim Measurements

Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma

Hydrogen Sulfide Protects Retinal Ganglion Cells Against Glaucomatous Injury In Vitro and In Vivo

Effect of Body Position on Epsicleral Venous Pressure in Healthy Subjects

Effect of Circulating Omentin-1 on the Retinal Circulation in Patients With Type 2 Diabetes Mellitus

Changes in Choroidal Blood Flow and Morphology in Response to Increase in Intraocular Pressure

Impact of Myopia on Corneal Biomechanics in Glaucoma and Nonglaucoma Patients

Progressive Deformation of the Optic Nerve Head and Peripapillary Structures by Graded Horizontal Duction

Effects of Intravitreal Dexamethasone Implants on Retinal Oxygen Saturation, Vessel Diameter, and Retrobulbar Blood Flow Velocity in ME Secondary to RVO

Genetic Deletion of the NOS3 Gene in CAV1 −/− Mice Restores Aqueous Humor Outflow Function

Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

Author Response: Comparison of MicroRNA Expression in Aqueous Humour of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

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