Glaucoma

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Clinical and Epidemiologic Research June 2017

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

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Jessica V. Jasien; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: anterior chamber of eye, catheterization, needle device, primates, recovery of function, time factors, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3225-3230. doi: 10.1167/iovs.17-21833

Glaucoma June 2017

The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients

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Naoki Kiyota; Yukihiro Shiga; Shiori Suzuki; Marika Sato; Naoko Takada; Shigeto Maekawa; Kazuko Omodaka; Kazuichi Maruyama; Hiroshi Kunikata; Toru Nakazawa
TAGS: oxygen, vascular flow, inspiration, glaucoma, open-angle glaucoma, hyperoxia, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3181-3188. doi: 10.1167/iovs.17-21648

Articles June 2017

Gait Implications of Visual Field Damage from Glaucoma

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Aleksandra Mihailovic; Bonnielin K. Swenor; David S. Friedman; Sheila K. West; Laura N. Gitlin; Pradeep Y. Ramulu
TAGS: gait, fertilization in vitro, glaucoma, visual fields, characteristics of gait
Trans. Vis. Sci. Tech.. 2017; 6(3):23. doi: 10.1167/tvst.6.3.23

Clinical and Epidemiologic Research June 2017

Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

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Wendy L. Marsh-Tootle; Elise Harb; Wei Hou; Qinghua Zhang; Heather A. Anderson; Katherine Weise; Thomas T. Norton; Jane Gwiazda; Leslie Hyman; for the Correction of Myopia Evaluation Trial (COMET) Study Group
TAGS: cohort studies, myopia, optic disk, musculoskeletal torsion, function, eye, optic nerve, young adult, torsion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3158-3171. doi: 10.1167/iovs.16-20860

Includes: Supplemental Content

Glaucoma June 2017

Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma

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Pieter W. M. Bonnemaijer; Colin Cook; Abhishek Nag; Christopher J. Hammond; Cornelia M. van Duijn; Hans G. Lemij; Caroline C. W. Klaver; Alberta A. H. J. Thiadens
TAGS: open-angle glaucoma, cornea, genetics, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3172-3180. doi: 10.1167/iovs.17-21716

Includes: Supplemental Content

Glaucoma June 2017

Biomechanical Responses of Lamina Cribrosa to Intraocular Pressure Change Assessed by Optical Coherence Tomography in Glaucoma Eyes

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Harry Quigley; Karun Arora; Sana Idrees; Francisco Solano; Sahar Bedrood; Christopher Lee; Joan Jefferys; Thao D. Nguyen
TAGS: glaucoma, optic disk, eye, intraocular pressure, cribriform plate, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2566-2577. doi: 10.1167/iovs.16-21321

Includes: Supplemental Content

Genetics June 2017

Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase

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Marie H. Solheim; Allen C. Clermont; Jonathon N. Winnay; Erlend Hallstensen; Anders Molven; Pål R. Njølstad; Eyvind Rødahl; C. Ronald Kahn
TAGS: congenital abnormality, mutation, 1-phosphatidylinositol 3-kinase, eye, intraocular pressure, iris, mice, immune reconstitution inflammatory syndrome, short syndrome
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3100-3106. doi: 10.1167/iovs.16-21347

Includes: Supplemental Content

Articles June 2017

Association between Corneal Biomechanical Properties with Ocular Response Analyzer and Also CorvisST Tonometry, and Glaucomatous Visual Field Severity

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Kazunori Hirasawa; Masato Matsuura; Hiroshi Murata; Shunsuke Nakakura; Yoshitaka Nakao; Yoshiaki Kiuchi; Ryo Asaoka
TAGS: glaucoma, tonometry, visual fields, cornea, eye
Trans. Vis. Sci. Tech.. 2017; 6(3):18. doi: 10.1167/tvst.6.3.18

Physiology and Pharmacology June 2017

A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility

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Enhua H. Zhou; Michael Paolucci; Thaddeus P. Dryja; Ted Manley; Chuanxi Xiang; Dennis S. Rice; Ganesh Prasanna; Amy Chen
TAGS: endothelin-1, perfusion, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2991-3003. doi: 10.1167/iovs.16-20974

Includes: Supplemental Content

Glaucoma June 2017

Parapapillary Deep-Layer Microvasculature Dropout in Glaucoma: Topographic Association With Glaucomatous Damage

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Eun Ji Lee; Seung Hyen Lee; Jeong-Ah Kim; Tae-Woo Kim
TAGS: glaucoma, open-angle glaucoma, eye, retinal nerve fiber layer, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3004-3010. doi: 10.1167/iovs.17-21918

Physiology and Pharmacology June 2017

VEGF as a Paracrine Regulator of Conventional Outflow Facility

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Ester Reina-Torres; Joanne C. Wen; Katy C. Liu; Guorong Li; Joseph M. Sherwood; Jason Y. H. Chang; Pratap Challa; Cassandra M. Flügel-Koch; W. Daniel Stamer; R. Rand Allingham; Darryl R. Overby
TAGS: vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, paracrine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1899-1908. doi: 10.1167/iovs.16-20779

Includes: Supplemental Content

Glaucoma June 2017

A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner

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Sally Miller; Sherry Shu-Jung Hu; Emma Leishman; Dan Morgan; Jim Wager-Miller; Ken Mackie; Heather B. Bradshaw; Alex Straiker
TAGS: signal transduction, eye, intraocular pressure, lipids, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2930-2938. doi: 10.1167/iovs.16-21330

Includes: Supplemental Content

Special Issue June 2017

In Vivo Confocal Imaging of the Conjunctiva as a Predictive Tool for the Glaucoma Filtration Surgery Outcome

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Rodolfo Mastropasqua; Vincenzo Fasanella; Lorenza Brescia; Francesco Oddone; Cesare Mariotti; Silvio Di Staso; Luca Agnifili
TAGS: glaucoma, filtering surgery, microscopy, confocal, preoperative care, surgical procedures, operative, blister, conjunctiva, diagnostic imaging, intraocular pressure, surgery specialty, glaucoma surgery
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO114-BIO120. doi: 10.1167/iovs.17-21795

Articles June 2017

Predicting Future Self-Reported Motor Vehicle Collisions in Subjects with Primary Open-Angle Glaucoma Using the Penalized Support Vector Machine Method

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Kenya Yuki; Ryo Asaoka; Sachiko Awano-Tanabe; Takeshi Ono; Daisuke Shiba; Hiroshi Murata; Kazuo Tsubota
TAGS: prednisone, glaucoma, accidents, traffic, disease vectors, open-angle glaucoma, questionnaires, spatial vectors, self-report
Trans. Vis. Sci. Tech.. 2017; 6(3):14. doi: 10.1167/tvst.6.3.14

Glaucoma June 2017

Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

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Hari Jayaram; Jay I. Phillips; Diana C. Lozano; Tiffany E. Choe; William O. Cepurna; Elaine C. Johnson; John C. Morrison; Devin M. Gattey; Julie A. Saugstad; Kate E. Keller
TAGS: polymerase chain reaction, hypertension, open-angle glaucoma, pilot projects, aqueous humor, micro rna
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2884-2890. doi: 10.1167/iovs.17-21844

Includes: Supplemental Content

Special Issue June 2017

Functional Activity of Matrix Metalloproteinases 2 and 9 in Tears of Patients With Glaucoma

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Prity Sahay; Aparna Rao; Debananda Padhy; Sarada Sarangi; Gopinath Das; Mamatha M. Reddy; Rahul Modak
TAGS: glaucoma, gelatin, gelatinase b, open-angle glaucoma, matrix metalloproteinases, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO106-BIO113. doi: 10.1167/iovs.17-21723

Glaucoma May 2017

A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients

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Teruhiko Hamanaka; Masae Kimura; Tetsuro Sakurai; Nobuo Ishida; Jun Yasuda; Masao Nagasaki; Naoki Nariai; Atsushi Endo; Kei Homma; Fumiki Katsuoka; Yoichi Matsubara; Masayuki Yamamoto; Nobuo Fuse
TAGS: mutation, open-angle glaucoma, trabeculectomy, eye, genetics, myoc gene, japanese
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2818-2831. doi: 10.1167/iovs.16-20646

Retina May 2017

Associations Between β-Peripapillary Atrophy and Reticular Pseudodrusen in Early Age-Related Macular Degeneration

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Aakriti Garg; Dana M. Blumberg; Lama A. Al-Aswad; Maris Oll; Suzanne Yzer; Max Forbes; Rando L. Allikmets; Srilaxmi Bearelly
TAGS: glaucoma, atrophy, diagnostic imaging, eye, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2810-2815. doi: 10.1167/iovs.16-20343

Glaucoma May 2017

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

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Julie A. Schaub; Elizabeth C. Kimball; Matthew R. Steinhart; Cathy Nguyen; Mary E. Pease; Ericka N. Oglesby; Joan L. Jefferys; Harry A. Quigley
TAGS: glaucoma, axon, retinal ganglion cells, eye, intraocular pressure, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2765-2773. doi: 10.1167/iovs.17-21761

Includes: Supplemental Content

Glaucoma May 2017

The Characteristics of Deep Optic Nerve Head Morphology in Myopic Normal Tension Glaucoma

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Jong Chul Han; Eun Jung Lee; Si Bum Kim; Changwon Kee
TAGS: optic disk, eye, glaucoma, normal-tension, morphology, retinal nerve fiber layer, language morphology
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2695-2704. doi: 10.1167/iovs.17-21791

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The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients

Gait Implications of Visual Field Damage from Glaucoma

Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

Genetic African Ancestry Is Associated With Central Corneal Thickness and Intraocular Pressure in Primary Open-Angle Glaucoma

Biomechanical Responses of Lamina Cribrosa to Intraocular Pressure Change Assessed by Optical Coherence Tomography in Glaucoma Eyes

Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase

Association between Corneal Biomechanical Properties with Ocular Response Analyzer and Also CorvisST Tonometry, and Glaucomatous Visual Field Severity

A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility

Parapapillary Deep-Layer Microvasculature Dropout in Glaucoma: Topographic Association With Glaucomatous Damage

VEGF as a Paracrine Regulator of Conventional Outflow Facility

A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner

In Vivo Confocal Imaging of the Conjunctiva as a Predictive Tool for the Glaucoma Filtration Surgery Outcome

Predicting Future Self-Reported Motor Vehicle Collisions in Subjects with Primary Open-Angle Glaucoma Using the Penalized Support Vector Machine Method

Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

Functional Activity of Matrix Metalloproteinases 2 and 9 in Tears of Patients With Glaucoma

A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients

Associations Between β-Peripapillary Atrophy and Reticular Pseudodrusen in Early Age-Related Macular Degeneration

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

The Characteristics of Deep Optic Nerve Head Morphology in Myopic Normal Tension Glaucoma

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