Glaucoma

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Glaucoma April 2018

BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork

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Humberto Hernandez; J. Cameron Millar; Stacy M. Curry; Abbot F. Clark; Colleen M. McDowell
TAGS: extracellular matrix, fibronectins, activins, tissue membrane, ocular hypertension, trabecular meshwork, eye, intraocular pressure, mice
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2154-2166. doi: 10.1167/iovs.17-23282

Includes: Supplemental Content

Glaucoma April 2018

Response of the Retinal Nerve Fiber Layer Reflectance and Thickness to Optic Nerve Crush

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Xiang-Run Huang; Wei Kong; Jianzhong Qiao
TAGS: optic nerve, retina, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2094-2103. doi: 10.1167/iovs.17-23148

Retinal Cell Biology April 2018

Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma

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Kei Akaiwa; Kazuhiko Namekata; Yuriko Azuchi; Hiroki Sano; Xiaoli Guo; Atsuko Kimura; Chikako Harada; Yoshinori Mitamura; Takayuki Harada
TAGS: mice, glaucoma, normal-tension, neuroprotection, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2080-2089. doi: 10.1167/iovs.17-23276

Glaucoma April 2018

Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy

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Min Hee Suh; Linda M. Zangwill; Patricia Isabel C. Manalastas; Akram Belghith; Adeleh Yarmohammadi; Tadamichi Akagi; Alberto Diniz-Filho; Luke Saunders; Robert N. Weinreb
TAGS: angiogram, atrophy, optical coherence tomography, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1995-2004. doi: 10.1167/iovs.17-23046

Clinical and Epidemiologic Research April 2018

Long Anterior Lens Zonules and Intraocular Pressure

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Daniel K. Roberts; Tricia L. Newman; Mary Flynn Roberts; Bruce A. Teitelbaum; Janis E. Winters
TAGS: lens, crystalline, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2015-2023. doi: 10.1167/iovs.17-23705

Includes: Supplemental Content

Articles April 2018

Predicting Visual Disability in Glaucoma With Combinations of Vision Measures

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Stephanie Lin; Aleksandra Mihailovic; Sheila K. West; Chris A. Johnson; David S. Friedman; Xiangrong Kong; Pradeep Y. Ramulu
TAGS: glaucoma, vision, vision tests, disability
Trans. Vis. Sci. Tech.. 2018; 7(2):22. doi: 10.1167/tvst.7.2.22

Special Issue April 2018

Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study

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Xiao-Yang Luo; Nicholas Y. Q. Tan; Miao-Li Chee; Yuan Shi; Yih-Chung Tham; Tien Yin Wong; Jie Jin Wang; Ching-Yu Cheng
TAGS: diabetes mellitus, diabetes mellitus, type 2, epidemiology, eye diseases, singapore, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD19-AMD25. doi: 10.1167/iovs.17-23013

Articles April 2018

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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Duri Kim; Ushasree Pattamatta; Elizabeth Kelly; Paul R. Healey; Nicole Carnt; Hans Zoellner; Andrew J. R. White
TAGS: angiotensins, irbesartan, cell culture techniques, receptor, angiotensin ii, angiotensin ii, fibroblast, cell count, reactive oxygen species
Trans. Vis. Sci. Tech.. 2018; 7(2):20. doi: 10.1167/tvst.7.2.20

Glaucoma April 2018

Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells

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Leona T. Y. Ho; Nikolai Skiba; Christoph Ullmer; Ponugoti Vasantha Rao
TAGS: actins, hypertension, transcription, genetic, fluorescent antibody technique, immunoblotting, muscle contraction, myosin light chain kinase, phosphorylation, phosphotransferases, trabecular meshwork, proteins, urea, transcriptional control, connective tissue growth factor, regulation
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1969-1984. doi: 10.1167/iovs.17-23702

Genetics April 2018

The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men

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David W. Collins; Harini V. Gudiseva; Venkata R. M. Chavali; Benjamin Trachtman; Meera Ramakrishnan; William T. Merritt III; Maxwell Pistilli; Rebecca A. Rossi; Stephanie Blachon; Prithvi S. Sankar; Eydie Miller-Ellis; Amanda Lehman; Victoria Addis; Joan M. O'Brien
TAGS: polymorphism, open-angle glaucoma, risk factors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1751-1759. doi: 10.1167/iovs.17-23277

Includes: Supplemental Content

Glaucoma April 2018

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets

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Hiroshi Murata; Linda M. Zangwill; Yuri Fujino; Masato Matsuura; Atsuya Miki; Kazunori Hirasawa; Masaki Tanito; Shiro Mizoue; Kazuhiko Mori; Katsuyoshi Suzuki; Takehiro Yamashita; Kenji Kashiwagi; Nobuyuki Shoji; Ryo Asaoka
TAGS: linear regression, datasets
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1897-1904. doi: 10.1167/iovs.17-22907

Glaucoma April 2018

Reduced Functional and Anatomic Interhemispheric Homotopic Connectivity in Primary Open-Angle Glaucoma: A Combined Resting State-fMRI and DTI Study

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Qian Wang; Weiwei Chen; Huaizhou Wang; Xun Zhang; Xiaoxia Qu; Ying Wang; Ting Li; Ningli Wang; Junfang Xian
TAGS: open-angle glaucoma, functional magnetic resonance imaging
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1861-1868. doi: 10.1167/iovs.17-23291

Articles April 2018

Validation of the UNC OCT Index for the Diagnosis of Early Glaucoma

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Jean-Claude Mwanza; Gary Lee; Donald L. Budenz; Joshua L. Warren; Michael Wall; Paul H. Artes; Thomas M. Callan; John G. Flanagan
TAGS: glaucoma
Trans. Vis. Sci. Tech.. 2018; 7(2):16. doi: 10.1167/tvst.7.2.16

Glaucoma April 2018

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

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Reiko Yamagishi-Kimura; Megumi Honjo; Takashi Komizo; Takashi Ono; Akiko Yagi; Jinhee Lee; Kazunori Miyata; Tomokazu Fujimoto; Toshihiro Inoue; Hidenobu Tanihara; Junko Nishida; Takatoshi Uchida; Yuka Araki; Makoto Aihara
TAGS: pilocarpine, pupil, intraocular pressure, diameter
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1844-1854. doi: 10.1167/iovs.18-23900

Visual Psychophysics and Physiological Optics April 2018

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts

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Nayuta Yoshioka; Barbara Zangerl; Jack Phu; Agnes Y. J. Choi; Sieu K. Khuu; Katherine Masselos; Michael P. Hennessy; Michael Kalloniatis
TAGS: glaucoma, cell count, cohort studies, ganglia, visual fields, photon correlation spectroscopy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1693-1703. doi: 10.1167/iovs.17-23683

Includes: Supplemental Content

Physiology and Pharmacology April 2018

A Novel Selective Soluble Guanylate Cyclase Activator, MGV354, Lowers Intraocular Pressure in Preclinical Models, Following Topical Ocular Dosing

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Ganesh Prasanna; Luciana Ferrara; Christopher Adams; Takeru Ehara; Byron Li; Louis Yang; Chuanxi Xiang; Christopher Thow Hing Ng; Sean Kim; Christopher Towler; Todd Topley; Cale McAllister; Malay Ghosh; Ronald Newton; Rebecca Stacy; Dennis S. Rice; Muneto Mogi
TAGS: cyclic gmp, glaucoma, macaca fascicularis, oryctolagus cuniculus, body tissue, eye, intraocular pressure, soluble guanylyl cyclase, transcriptional activation
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1704-1716. doi: 10.1167/iovs.18-23772

Includes: Supplemental Content

Articles March 2018

Evaluation of a Region-of-Interest Approach for Detecting Progressive Glaucomatous Macular Damage on Optical Coherence Tomography

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Zhichao Wu; Denis S. D. Weng; Abinaya Thenappan; Robert Ritch; Donald C. Hood
TAGS: glaucoma, diagnostic imaging, eye, optical coherence tomography
Trans. Vis. Sci. Tech.. 2018; 7(2):14. doi: 10.1167/tvst.7.2.14

Articles March 2018

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

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Ian Pitha; Elizabeth C. Kimball; Ericka N. Oglesby; Mary Ellen Pease; Jie Fu; Julie Schaub; Yoo-Chun Kim; Qi Hu; Justin Hanes; Harry A. Quigley
TAGS: glaucoma, injection of therapeutic agent, retinal ganglion cells, eye, intraocular pressure, dorzolamide, eyedrops, cell-derived microparticles
Trans. Vis. Sci. Tech.. 2018; 7(2):13. doi: 10.1167/tvst.7.2.13

Includes: Supplemental Content

Articles March 2018

Reducing Spatial Uncertainty Through Attentional Cueing Improves Contrast Sensitivity in Regions of the Visual Field With Glaucomatous Defects

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Jack Phu; Michael Kalloniatis; Sieu K. Khuu
TAGS: glaucoma, contrast sensitivity, visual fields
Trans. Vis. Sci. Tech.. 2018; 7(2):8. doi: 10.1167/tvst.7.2.8

Glaucoma March 2018

Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography

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Sunee Chansangpetch; Anwell Nguyen; Marta Mora; Mai Badr; Mingguang He; Travis C. Porco; Shan C. Lin
TAGS: anterior chamber of eye, lens (device), software, eye, nose, immune reconstitution inflammatory syndrome, optical coherence tomography, bland-altman plot
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1554-1561. doi: 10.1167/iovs.17-23574

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BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork

Response of the Retinal Nerve Fiber Layer Reflectance and Thickness to Optic Nerve Crush

Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma

Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy

Long Anterior Lens Zonules and Intraocular Pressure

Predicting Visual Disability in Glaucoma With Combinations of Vision Measures

Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells

The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men

Validating Variational Bayes Linear Regression Method With Multi-Central Datasets

Reduced Functional and Anatomic Interhemispheric Homotopic Connectivity in Primary Open-Angle Glaucoma: A Combined Resting State-fMRI and DTI Study

Validation of the UNC OCT Index for the Diagnosis of Early Glaucoma

Interaction Between Pilocarpine and Ripasudil on Intraocular Pressure, Pupil Diameter, and the Aqueous-Outflow Pathway

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts

A Novel Selective Soluble Guanylate Cyclase Activator, MGV354, Lowers Intraocular Pressure in Preclinical Models, Following Topical Ocular Dosing

Evaluation of a Region-of-Interest Approach for Detecting Progressive Glaucomatous Macular Damage on Optical Coherence Tomography

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP–Glaucoma

Reducing Spatial Uncertainty Through Attentional Cueing Improves Contrast Sensitivity in Regions of the Visual Field With Glaucomatous Defects

Agreement of Anterior Segment Parameters Obtained From Swept-Source Fourier-Domain and Time-Domain Anterior Segment Optical Coherence Tomography

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