Glaucoma

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Glaucoma June 2018

A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

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Brian C. Samuels; John T. Siegwart; Wenjie Zhan; Lisa Hethcox; Melissa Chimento; Ryan Whitley; J. Crawford Downs; Christopher A. Girkin
TAGS: glaucoma, animal model, tupaia, tupaiidae, diagnostic imaging, eye, intraocular pressure, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3136-3143. doi: 10.1167/iovs.18-24261

Glaucoma June 2018

The Contribution of Sulfated Glycosaminoglycans to the Inflation Response of the Human Optic Nerve Head

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Dan E. Midgett; Joan L. Jefferys; Harry A. Quigley; Thao D. Nguyen
TAGS: buffers, glycosaminoglycans, economic inflation, optic disk, enzymes, eye, catabolism
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3144-3154. doi: 10.1167/iovs.18-23845

Glaucoma June 2018

Trichostatin A Ameliorates Conjunctival Fibrosis in a Rat Trabeculectomy Model

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Mi Sun Sung; Gwang Hyeon Eom; Soo Jin Kim; So Young Kim; Hwan Heo; Sang Woo Park
TAGS: fibrosis, histone deacetylase, postoperative care, steroids, blister, conjunctiva, eyedrops, trabeculectomy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3115-3123. doi: 10.1167/iovs.18-23826

Articles June 2018

Development of a Visual Field Simulation Model of Longitudinal Point-Wise Sensitivity Changes From a Clinical Glaucoma Cohort

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Zhichao Wu; Felipe A. Medeiros
TAGS: glaucoma, cohort studies, visual fields, eye, visual field testing
Trans. Vis. Sci. Tech.. 2018; 7(3):22. doi: 10.1167/tvst.7.3.22

Glaucoma June 2018

Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera

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Alexandra Gogola; Ning-Jiun Jan; Bryn Brazile; Po Lam; Kira L. Lathrop; Kevin C. Chan; Ian A. Sigal
TAGS: collagen, cornea, eye, sclera
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2987-2998. doi: 10.1167/iovs.17-23474

Includes: Supplemental Content

Articles June 2018

A Method Using Goldmann Stimulus Sizes I to V–Measured Sensitivities to Predict Lead Time Gained to Visual Field Defect Detection in Early Glaucoma

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Jack Phu; Sieu K. Khuu; Bang V. Bui; Michael Kalloniatis
TAGS: glaucoma, scotoma, visual field defects
Trans. Vis. Sci. Tech.. 2018; 7(3):17. doi: 10.1167/tvst.7.3.17

Includes: Supplemental Content

Glaucoma June 2018

microRNA Profiling in Glaucoma Eyes With Varying Degrees of Optic Neuropathy by Using Next-Generation Sequencing

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Yaoming Liu; Yang Chen; Yayi Wang; Xinyu Zhang; Kai Gao; Shida Chen; Xiulan Zhang
TAGS: hypertension, glaucoma, cataract, open-angle glaucoma, eye, optic nerve disorders, micrornas, massively-parallel genome sequencing
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2955-2966. doi: 10.1167/iovs.17-23599

Includes: Supplemental Content

Articles June 2018

Mechanical Evaluation of Retinal Damage Associated With Blunt Craniomaxillofacial Trauma: A Simulation Analysis

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Xiaoqi Geng; Xiaoyu Liu; Wei Wei; Yawei Wang; Lizhen Wang; Kinon Chen; Hongqiang Huo; Yuanjie Zhu; Yubo Fan
TAGS: cranium, wounds and injuries, eye
Trans. Vis. Sci. Tech.. 2018; 7(3):16. doi: 10.1167/tvst.7.3.16

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology June 2018

Optic Nerve Sheath Tethering in Adduction Occurs in Esotropia and Hypertropia, But Not in Exotropia

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Soh Youn Suh; Robert A. Clark; Joseph L. Demer
TAGS: magnetic resonance imaging, esotropia, exotropia, hypertropia, eye, optic nerve, optic nerve sheath, gaze, adduction, spinal tethering
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2899-2904. doi: 10.1167/iovs.18-24305

Retina June 2018

Biomechanical Properties of Bruch's Membrane–Choroid Complex and Their Influence on Optic Nerve Head Biomechanics

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Xiaofei Wang; Clarence Ken Guan Teoh; Anita S. Y. Chan; Sathiyan Thangarajoo; Jost B. Jonas; Michaël J. A. Girard
TAGS: biomechanics, bruch's basal membrane, optic disk, rupture, body tissue, choroid, eye, intraocular pressure, sclera, raised intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2808-2817. doi: 10.1167/iovs.17-22069

Includes: Supplemental Content

Articles June 2018

Comparison of Widefield and Circumpapillary Circle Scans for Detecting Glaucomatous Neuroretinal Thinning on Optical Coherence Tomography

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Zhichao Wu; Denis S. D. Weng; Abinaya Thenappan; Rashmi Rajshekhar; Robert Ritch; Donald C. Hood
TAGS: glaucoma, optic disk, eye, optical coherence tomography, retinal nerve fiber layer
Trans. Vis. Sci. Tech.. 2018; 7(3):11. doi: 10.1167/tvst.7.3.11

Glaucoma June 2018

VIP Regulates Morphology and F-Actin Distribution of Schlemm's Canal in a Chronic Intraocular Pressure Hypertension Model via the VPAC2 Receptor

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Liwen Chen; Mu Li; Zhaoxia Luo; Xiaoqin Yan; Ke Yao; Yin Zhao; Hong Zhang
TAGS: actins, hypertension, eye, intraocular pressure, schlemm's canal, morphology, vipr2 gene, language morphology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2848-2860. doi: 10.1167/iovs.17-22688

Includes: Supplemental Content

Glaucoma June 2018

Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression

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Mark Christopher; Akram Belghith; Robert N. Weinreb; Christopher Bowd; Michael H. Goldbaum; Luke J. Saunders; Felipe A. Medeiros; Linda M. Zangwill
TAGS: glaucoma, optical coherence tomography, retinal nerve fiber layer, unsupervised machine learning
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2748-2756. doi: 10.1167/iovs.17-23387

Glaucoma June 2018

Mapping the Central 10° Visual Field to the Optic Nerve Head Using the Structure–Function Relationship

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Yuri Fujino; Hiroshi Murata; Masato Matsuura; Mieko Yanagisawa; Nobuyuki Shoji; Kenji Inoue; Junkichi Yamagami; Ryo Asaoka
TAGS: optic disk, visual fields, eye
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2801-2807. doi: 10.1167/iovs.17-23485

Glaucoma June 2018

Peripapillary Retinoschisis in Glaucoma: Association With Progression and OCT Signs of Müller Cell Involvement

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Brad Fortune; Kelly N. Ma; Stuart K. Gardiner; Shaban Demirel; Steven L. Mansberger
TAGS: glaucoma, eye, retina, retinoschisis, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2818-2827. doi: 10.1167/iovs.18-24160

Glaucoma June 2018

The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration

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Joana Galvao; Keiichiro Iwao; Akintomide Apara; Yan Wang; Masoumeh Ashouri; Tejas Nimish Shah; Murray Blackmore; Noelia J. Kunzevitzky; Darcie L. Moore; Jeffrey L. Goldberg
TAGS: axon, genes
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2736-2747. doi: 10.1167/iovs.17-23319

Includes: Supplemental Content

Glaucoma June 2018

Active Lymphatic Drainage From the Eye Measured by Noninvasive Photoacoustic Imaging of Near-Infrared Nanoparticles

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Yeni H. Yücel; Kirsten Cardinell; Shireen Khattak; Xun Zhou; Michael Lapinski; Fang Cheng; Neeru Gupta
TAGS: fluorescence, injection of therapeutic agent, diagnostic imaging, eye, mice, drainage of lymphatics, nanoparticles
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2699-2707. doi: 10.1167/iovs.17-22850

Includes: Supplemental Content

Articles May 2018

Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury

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Lin Fu; Frederic K. Fung; Amy Cheuk-Yin Lo; Yau-Kei Chan; Kwok-Fai So; Ian Yat-Hin Wong; Kendrick Co Shih; Jimmy Shiu-Ming Lai
TAGS: electric stimulation, ocular hypertension, retinal ganglion cells, wounds and injuries, eye
Trans. Vis. Sci. Tech.. 2018; 7(3):7. doi: 10.1167/tvst.7.3.7

Physiology and Pharmacology May 2018

Effects of Topical Latanoprost on Intraocular Pressure and Myopia Progression in Young Guinea Pigs

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Nevin W. El-Nimri; Christine F. Wildsoet
TAGS: caviidae, myopia, eye, intraocular pressure, latanoprost
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2644-2651. doi: 10.1167/iovs.17-22890

Glaucoma May 2018

Proteomic Alterations in Aqueous Humor From Patients With Primary Open Angle Glaucoma

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Shruti Sharma; Kathryn E. Bollinger; Sai Karthik Kodeboyina; Wenbo Zhi; Jordan Patton; Shan Bai; Blake Edwards; Lane Ulrich; David Bogorad; Ashok Sharma
TAGS: hypertension, open-angle glaucoma, aqueous humor, proteins, proteomics
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2635-2643. doi: 10.1167/iovs.17-23434

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A Novel Tree Shrew ( Tupaia belangeri ) Model of Glaucoma

The Contribution of Sulfated Glycosaminoglycans to the Inflation Response of the Human Optic Nerve Head

Trichostatin A Ameliorates Conjunctival Fibrosis in a Rat Trabeculectomy Model

Development of a Visual Field Simulation Model of Longitudinal Point-Wise Sensitivity Changes From a Clinical Glaucoma Cohort

Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera

A Method Using Goldmann Stimulus Sizes I to V–Measured Sensitivities to Predict Lead Time Gained to Visual Field Defect Detection in Early Glaucoma

microRNA Profiling in Glaucoma Eyes With Varying Degrees of Optic Neuropathy by Using Next-Generation Sequencing

Mechanical Evaluation of Retinal Damage Associated With Blunt Craniomaxillofacial Trauma: A Simulation Analysis

Optic Nerve Sheath Tethering in Adduction Occurs in Esotropia and Hypertropia, But Not in Exotropia

Biomechanical Properties of Bruch's Membrane–Choroid Complex and Their Influence on Optic Nerve Head Biomechanics

Comparison of Widefield and Circumpapillary Circle Scans for Detecting Glaucomatous Neuroretinal Thinning on Optical Coherence Tomography

VIP Regulates Morphology and F-Actin Distribution of Schlemm's Canal in a Chronic Intraocular Pressure Hypertension Model via the VPAC2 Receptor

Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression

Mapping the Central 10° Visual Field to the Optic Nerve Head Using the Structure–Function Relationship

Peripapillary Retinoschisis in Glaucoma: Association With Progression and OCT Signs of Müller Cell Involvement

The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration

Active Lymphatic Drainage From the Eye Measured by Noninvasive Photoacoustic Imaging of Near-Infrared Nanoparticles

Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury

Effects of Topical Latanoprost on Intraocular Pressure and Myopia Progression in Young Guinea Pigs

Proteomic Alterations in Aqueous Humor From Patients With Primary Open Angle Glaucoma

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