Translational Research

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Articles December 2019

Impact of Pupil Diameter on Objective Refraction Determination and Predicted Visual Acuity

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Heather A. Anderson; Ayeswarya Ravikumar; Julia S. Benoit; Jason D. Marsack
TAGS: diameter, pupil, refraction, visual acuity, eye
Trans. Vis. Sci. Tech.. 2019; 8(6):32. doi: https://doi.org/10.1167/tvst.8.6.32

Articles December 2019

Ability of Nonswelling Polyethylene Glycol-Based Vitreous Hydrogel to Maintain Transparency in the Presence of Vitreous Hemorrhage

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Sujin Hoshi; Fumiki Okamoto; Tomoya Murakami; Takamasa Sakai; Yuko Shinohara; Tomohiko Fujii; Masayoshi Nakatani; Tetsuro Oshika
TAGS: glycols, hydrogel, polyethylene, transparency, vitreous body, vitreous hemorrhage, gel, blood groups
Trans. Vis. Sci. Tech.. 2019; 8(6):33. doi: https://doi.org/10.1167/tvst.8.6.33

Articles December 2019

Assessment of Corneal Fluorescein Staining in Different Dry Eye Subtypes Using Digital Image Analysis

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Marco Pellegrini; Federico Bernabei; Fabiana Moscardelli; Aldo Vagge; Riccardo Scotto; Cristina Bovone; Vincenzo Scorcia; Giuseppe Giannaccare
TAGS: cornea, digital image analysis, dry eye syndromes, fluorescein stain method, reliability
Trans. Vis. Sci. Tech.. 2019; 8(6):34. doi: https://doi.org/10.1167/tvst.8.6.34

Articles December 2019

SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa

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Chulbul M. Ahmed; Brian T. Dwyer; Alla Romashko; Steve Van Adestine; Eun-Hee Park; Zhen Lou; Devin Welty; Serene Josiah; Anneli Savinainen; Bohong Zhang; Alfred S. Lewin
TAGS: molecular chaperones, opsin, rhodopsin, animal model, retinitis pigmentosa, pharmacology, mice, photoreceptors
Trans. Vis. Sci. Tech.. 2019; 8(6):30. doi: https://doi.org/10.1167/tvst.8.6.30

Includes: Supplemental Content

Articles December 2019

Systematic Screening, Rational Development, and Initial Optimization of Efficacious RNA Silencing Agents for Human Rod Opsin Therapeutics

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Edwin H. Yau; Robert T. Taggart; Mohammed Zuber; Alexandria J. Trujillo; Zahra S. Fayazi; Mark C. Butler; Lowell G. Sheflin; Jennifer B. Breen; Dian Yu; Jack M. Sullivan
TAGS: catalytic rna, opsin, rna, rna interference, rna, messenger, screening, therapeutics, cytokinesis, superior epigastric artery perforator flap, mutation
Trans. Vis. Sci. Tech.. 2019; 8(6):28. doi: https://doi.org/10.1167/tvst.8.6.28

Includes: Supplemental Content

Articles December 2019

Validation of Computerized Quantification of Ocular Redness

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Ekaterina Sirazitdinova; Marlies Gijs; Christian J. F. Bertens; Tos T. J. M. Berendschot; Rudy M. M. A. Nuijts; Thomas M. Deserno
TAGS: automation, color, conjunctiva, eye, machine learning, reliability, sclera, software, pixel, frequency distribution
Trans. Vis. Sci. Tech.. 2019; 8(6):31. doi: https://doi.org/10.1167/tvst.8.6.31

Includes: Supplemental Content

Articles December 2019

Efficacy and Safety of Transglutaminase-Induced Corneal Stiffening in Rabbits

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Yuan Wu; Wenjing Song; Yun Tang; Ahmed Elsheikh; Yingfeng Shao; Xiaoming Yan
TAGS: cornea, corneal collagen cross-linking, oryctolagus cuniculus, safety, transglutaminases, keratocytes, ultraviolet a radiation, endothelium
Trans. Vis. Sci. Tech.. 2019; 8(6):27. doi: https://doi.org/10.1167/tvst.8.6.27

Articles December 2019

Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study

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Nan Su; Sigrid März; Tanja Plagemann; Jiahui Cao; Hans-Joachim Schnittler; Nicole Eter; Peter Heiduschka
TAGS: antibodies, integral membrane proteins, mice, microglia, retina, lasers, brain, macrophage-1 antigen
Trans. Vis. Sci. Tech.. 2019; 8(6):29. doi: https://doi.org/10.1167/tvst.8.6.29

Articles December 2019

Gas-Graft Coverage After DMEK: A Clinically Validated Numeric Study

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Jan O. Pralits; Mark Alberti; Javier Cabrerizo
TAGS: descemet membrane endothelial keratoplasty, tissue transplants, eye
Trans. Vis. Sci. Tech.. 2019; 8(6):9. doi: https://doi.org/10.1167/tvst.8.6.9

Includes: Supplemental Content

Articles December 2019

Biomechanical and Morphologic Effects of Collagen Cross-Linking in Human Tarsus

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Shoaib Ugradar; Alan Le; Michael Lesgart; Robert A. Goldberg; Daniel Rootman; Joseph L. Demer
TAGS: ankle, body tissue, corneal collagen cross-linking, cross-linking, tarsal bones, microscopes, transmission electron, riboflavin, collagen, ultraviolet a radiation, radiation
Trans. Vis. Sci. Tech.. 2019; 8(6):25. doi: https://doi.org/10.1167/tvst.8.6.25

Articles December 2019

OCTA-Based Identification of Different Vascular Patterns in Stargardt Disease

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Alessandro Arrigo; Francesco Romano; Emanuela Aragona; Carlo di Nunzio; Andrea Sperti; Francesco Bandello; Maurizio Battaglia Parodi
TAGS: stargardt's disease
Trans. Vis. Sci. Tech.. 2019; 8(6):26. doi: https://doi.org/10.1167/tvst.8.6.26

Articles December 2019

Towards Automatically Controlled Dosing for Selective Laser Trabeculoplasty

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Katharina Bliedtner; Eric Seifert; Ralf Brinkmann
TAGS: laser trabeculoplasty, lasers, modified barium swallow, optics, feedback, sensitivity and specificity, datasets, eye, wheelchair ramps, suidae
Trans. Vis. Sci. Tech.. 2019; 8(6):24. doi: https://doi.org/10.1167/tvst.8.6.24

Articles December 2019

Deep Learning Algorithm for Automated Diagnosis of Retinopathy of Prematurity Plus Disease

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Zachary Tan; Samantha Simkin; Connie Lai; Shuan Dai
TAGS: deep learning, retinopathy of prematurity, screening, negative predictive value, training
Trans. Vis. Sci. Tech.. 2019; 8(6):23. doi: https://doi.org/10.1167/tvst.8.6.23

Articles November 2019

Objective Measurement of Local Rod and Cone Function Using Gaze-Controlled Chromatic Pupil Campimetry in Healthy Subjects

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Carina Kelbsch; Katarina Stingl; Melanie Kempf; Torsten Strasser; Ronja Jung; Laura Kuehlewein; Helmut Wilhelm; Tobias Peters; Barbara Wilhelm; Krunoslav Stingl
TAGS: constriction procedure, gaze, pupil, pupil reaction, retinal cone, rod photoreceptors
Trans. Vis. Sci. Tech.. 2019; 8(6):19. doi: https://doi.org/10.1167/tvst.8.6.19

Articles November 2019

Dietary Spirulina Supplementation Protects Visual Function From Photostress by Suppressing Retinal Neurodegeneration in Mice

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Tomohiro Okamoto; Hirohiko Kawashima; Hideto Osada; Eriko Toda; Kohei Homma; Norihiro Nagai; Yasuyuki Imai; Kazuo Tsubota; Yoko Ozawa
TAGS: diet, light exposure, mice, nerve degeneration, photoreceptors, retina, vision, monocyte chemoattractant protein-1, electroretinography, proteins
Trans. Vis. Sci. Tech.. 2019; 8(6):20. doi: https://doi.org/10.1167/tvst.8.6.20

Articles November 2019

Deep Learning for Automatically Visual Evoked Potential Classification During Surgical Decompression of Sellar Region Tumors

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Nidan Qiao; Mengju Song; Zhao Ye; Wenqiang He; Zengyi Ma; Yongfei Wang; Yuyan Zhang; Xuefei Shou
TAGS: decompression, surgical, deep learning, evoked potentials, visual, neoplasms
Trans. Vis. Sci. Tech.. 2019; 8(6):21. doi: https://doi.org/10.1167/tvst.8.6.21

Includes: Supplemental Content

Articles November 2019

Association Between Arterial Blood Gas Variation and Intraocular Pressure in Healthy Subjects Exposed to Acute Short-Term Hypobaric Hypoxia

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Yuan Xie; Yiquan Yang; Ying Han; Diya Yang; Yunxiao Sun; Xinmao Wang; Anh Hong Nguyen; Yihan Chen; Jiaxin Tian; Qing Zhang; Chen Xin; Kai Cao; Huaizhou Wang; Xiaofang Liu; Guozhong Wang; Ningli Wang
TAGS: arterial blood gas, hypoxia, intraocular pressure, bicarbonates, sea level
Trans. Vis. Sci. Tech.. 2019; 8(6):22. doi: https://doi.org/10.1167/tvst.8.6.22

Review November 2019

Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?

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Bert Van den Bogerd; Nadia Zakaria; Bianca Adam; Steffi Matthyssen; Carina Koppen; Sorcha Ní Dhubhghaill
TAGS: cornea, endothelial cells, endothelium, adenosine triphosphatases, phenotype, genotype
Trans. Vis. Sci. Tech.. 2019; 8(6):13. doi: https://doi.org/10.1167/tvst.8.6.13

Includes: Supplemental Content

Articles November 2019

An Objective Comparison of Light Intensity and Near-Visual Tasks Between Rural and Urban School Children in China by a Wearable Device Clouclip

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Longbo Wen; Qian Cheng; Weizhong Lan; Yingpin Cao; Xiaoning Li; Yiqiu Lu; Zhenghua Lin; Lun Pan; Haogang Zhu; Zhikuan Yang
TAGS: china, light intensity, school (environment), school-age child, student, wearable devices, weekend, myopia, light exposure
Trans. Vis. Sci. Tech.. 2019; 8(6):15. doi: https://doi.org/10.1167/tvst.8.6.15

Articles November 2019

Comparing Spatial Contrast Sensitivity Functions Measured With Digit and Grating Stimuli

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Haiyan Zheng; Menglu Shen; Xianghang He; Rong Cui; Luis Andres Lesmes; Zhong-Lin Lu; Fang Hou
TAGS: cerebrospinal fluid analysis, colony-stimulating factors, contrast sensitivity, spatial frequency, precision, reliability, psychometrics
Trans. Vis. Sci. Tech.. 2019; 8(6):16. doi: https://doi.org/10.1167/tvst.8.6.16

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Impact of Pupil Diameter on Objective Refraction Determination and Predicted Visual Acuity

Ability of Nonswelling Polyethylene Glycol-Based Vitreous Hydrogel to Maintain Transparency in the Presence of Vitreous Hemorrhage

Assessment of Corneal Fluorescein Staining in Different Dry Eye Subtypes Using Digital Image Analysis

SRD005825 Acts as a Pharmacologic Chaperone of Opsin and Promotes Survival of Photoreceptors in an Animal Model of Autosomal Dominant Retinitis Pigmentosa

Systematic Screening, Rational Development, and Initial Optimization of Efficacious RNA Silencing Agents for Human Rod Opsin Therapeutics

Validation of Computerized Quantification of Ocular Redness

Efficacy and Safety of Transglutaminase-Induced Corneal Stiffening in Rabbits

Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study

Gas-Graft Coverage After DMEK: A Clinically Validated Numeric Study

Biomechanical and Morphologic Effects of Collagen Cross-Linking in Human Tarsus

OCTA-Based Identification of Different Vascular Patterns in Stargardt Disease

Towards Automatically Controlled Dosing for Selective Laser Trabeculoplasty

Deep Learning Algorithm for Automated Diagnosis of Retinopathy of Prematurity Plus Disease

Objective Measurement of Local Rod and Cone Function Using Gaze-Controlled Chromatic Pupil Campimetry in Healthy Subjects

Dietary Spirulina Supplementation Protects Visual Function From Photostress by Suppressing Retinal Neurodegeneration in Mice

Deep Learning for Automatically Visual Evoked Potential Classification During Surgical Decompression of Sellar Region Tumors

Association Between Arterial Blood Gas Variation and Intraocular Pressure in Healthy Subjects Exposed to Acute Short-Term Hypobaric Hypoxia

Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?

An Objective Comparison of Light Intensity and Near-Visual Tasks Between Rural and Urban School Children in China by a Wearable Device Clouclip

Comparing Spatial Contrast Sensitivity Functions Measured With Digit and Grating Stimuli

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