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Retina December 2024

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

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Maria Ludovica Ruggeri; Marzia Passamonti; Alberto Quarta; Olgers Koci; Annamaria Porreca; Marta Di Nicola; Lucio Zeppa; Rodolfo Mastropasqua; Lisa Toto
TAGS: central serous chorioretinopathy
Trans. Vis. Sci. Tech.. 2024; 13(12):14. https://doi.org/10.1167/tvst.13.12.14

Retina February 2025

Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population

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Takahiro Kogo; Yuki Muraoka; Masayuki Hata; Masaharu Ishikura; Naomi Nishigori; Yuki Akiyama; Naoko Ueda-Arakawa; Manabu Miyata; Sotaro Ooto; Ayako Takahashi; Masahiro Miyake; Akitaka Tsujikawa
TAGS: discharge, body substance, drainage procedure, epithelium, eye, fovea centralis, japanese, pigment, polypoidal choroidal vasculopathy, drusen, face
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):70. https://doi.org/10.1167/iovs.66.2.70

Includes: Supplemental Content

Retina March 2025

Effects of a Hyperbaric Normoxic Environment on the Retina and Choroid

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Nur Demir; Belma Kayhan; Yavuz Aslan
TAGS: choroid, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):47. https://doi.org/10.1167/iovs.66.3.47

Immunology and Microbiology February 2025

Elevated Plasma Complement Factors in CRB1 -Associated Inherited Retinal Dystrophies

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Lude Moekotte; Joke H. de Boer; Sanne Hiddingh; Aafke de Ligt; Xuan-Thanh-An Nguyen; Carel B. Hoyng; Chris F. Inglehearn; Martin McKibbin; Tina M. Lamey; Jennifer A. Thompson; Fred K. Chen; Terri L. McLaren; Alaa AlTalbishi; Daan M. Panneman; Erica G. M. Boonen; Sandro Banfi; Béatrice Bocquet; Isabelle Meunier; Elfride De Baere; Robert Koenekoop; Monika Ołdak; Carlo Rivolta; Lisa Roberts; Raj Ramesar; Rasa Strupaitė-Šileikienė; Susanne Kohl; G. Jane Farrar; Marion van Vugt; Jessica van Setten; Susanne Roosing; L. Ingeborgh van den Born; Camiel J. F. Boon; Maria M. van Genderen; Jonas J. W. Kuiper
TAGS: complement system proteins, hereditary retinal dystrophy, plasma, proteins, genotype, proteome, genes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):55. https://doi.org/10.1167/iovs.66.2.55

Includes: Supplemental Content

Retina February 2025

OCT Angiography of Type 1 Macular Neovascularization in AMD: A Morphometric Evaluation

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Maria Cristina Savastano; Claudia Fossataro; Matteo Mario Carlà; Valentina Cestrone; Ilaria Biagini; Clara Rizzo; Raphael Kilian; Sandrine A. Zweifel; Daniel R. Muth; Francesco Faraldi; Stanislao Rizzo; David Sarraf
TAGS: macular neovascularization, angiogram, biological markers
Trans. Vis. Sci. Tech.. 2025; 14(2):23. https://doi.org/10.1167/tvst.14.2.23

Genetics February 2025

Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel

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Sarah van der Ende; Karen Bedard; Karin Wallace; Michael P. Mackley; Mathew Nightingale; Daniel Gaston; M. Jill Beis; Marissa A. Leblanc; Roxanne Gillett; Alex V. Levin; Ian H. Clark; Élise Héon; Rajeev H. Muni; Elias I. Traboulsi; Christopher J. Lyons; Christopher R. McMaster; Johane M. Robitaille; on behalf of The FEVR Consortium
TAGS: familial exudative vitreoretinopathies, genes, proband
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):23. https://doi.org/10.1167/iovs.66.2.23

Includes: Supplemental Content

Retina February 2025

Clinical, Genetic, Imaging and Electrophysiological Findings in a Cohort of Patients With GUCA1A -Associated Retinopathy

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Gilad Allon; Siying Lin; Anthony G. Robson; Gavin Arno; Magella M. Neveu; Pirro G. Hysi; Michel Michaelides; Andrew R. Webster; Omar A. Mahroo
TAGS: cohort studies, diagnostic imaging, genetics, retinal diseases, visual acuity, electrophysiology, family, eye, vision
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):50. https://doi.org/10.1167/iovs.66.2.50

Retina February 2025

Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment

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Yijing Chen; Xiaoya Zhang; Yanli Zhang; Shian Zhang; Yu Huo; Yubo Wu; Lijun Shen; Jianbo Mao
TAGS: anti-vascular endothelial growth factor therapy, aqueous humor, exudative age-related macular degeneration, metabolites, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):37. https://doi.org/10.1167/iovs.66.2.37

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography

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Yi Wang; Tengbo Rao; Jichao Zhou; Debo You; Jiarui Yang; Lingge Suo
TAGS: angiogram, eye, graves' ophthalmopathy, optic disk, cortical blindness, vascular flow, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):25. https://doi.org/10.1167/iovs.66.2.25

Includes: Supplemental Content

Retina August 2024

Subthreshold Micropulse Laser Versus Oral Spironolactone in Chronic Central Serous Chorioretinopathy: A Quasi-Randomized Controlled Trial

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Sheng Gao; Ge Ge; Yun Zhang; Meixia Zhang
TAGS: central serous chorioretinopathy, lasers, spironolactone
Trans. Vis. Sci. Tech.. 2024; 13(8):19. https://doi.org/10.1167/tvst.13.8.19

Includes: Supplemental Content

Retina January 2025

Visual Performance and Predictive OCT Biomarkers in Epiretinal Membrane Assessment: Beyond Distance Visual Acuity

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Francesco Gelormini; Federico Ricardi; Guglielmo Parisi; Veronica Vallino; Beatrice Ghezzo; Claudia Cucciarelli; Paola Marolo; Maria Vittoria Cicinelli; Andrea Govetto; Mario R. Romano; Enrico Borrelli; Michele Reibaldi
TAGS: biological markers, epiretinal membrane, visual acuity, reading (activity), near visual acuity
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):31. https://doi.org/10.1167/iovs.66.1.31

Retina January 2025

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

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Katharina Wall; Lilith P. Arend; Leon von der Emde; Marlene Saßmannshausen; Frank G. Holz; Thomas Ach
TAGS: diabetes mellitus, diagnostic imaging, optical coherence tomography, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2025; 14(1):12. https://doi.org/10.1167/tvst.14.1.12

Retina December 2024

Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration

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Pasquale Viggiano; Giacomo Boscia; Giuseppe Giannaccare; Michele Santoro; Giovanni Petrara; Ciro Borriello; Enrico Borrelli; Michele Reibaldi; Maria Oliva Grassi; Giovanni Alessio; Francesco Boscia
TAGS: atrophoderma maculatum, exudative age-related macular degeneration, retina, anti-vascular endothelial growth factor therapy, macular neovascularization, follow-up visit
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):45. https://doi.org/10.1167/iovs.65.14.45

Artificial Intelligence December 2024

A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

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Chubin Ou; Xifei Wei; Lin An; Jia Qin; Min Zhu; Mei Jin; Xiangbin Kong
TAGS: deep learning, face, multicenter studies
Trans. Vis. Sci. Tech.. 2024; 13(12):31. https://doi.org/10.1167/tvst.13.12.31

Includes: Supplemental Content

Retina December 2024

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

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Lukas Goerdt; Jose Luis Rodriguez Garcia; Sandrine H. Künzel; Kristina Pfau; Kristin Raming; Simone Tzaridis; Matthias Schmid; Frank G. Holz; Ben Isselmann; Leonie Weinhold; Sarah Thiele
TAGS: patient prognosis, telangiectasis, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):36. https://doi.org/10.1167/iovs.65.14.36

Retina July 2024

Differential Expression of Sex-Steroid Receptors in the Choroid Aligns With Central Serous Chorioretinopathy Sex Prevalence Across Different Ages

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Sekar Galuh; Onno C. Meijer; Joost Brinks; Reinier O. Schlingemann; Camiel J. F. Boon; Robert M. Verdijk; Elon H. C. van Dijk
TAGS: central serous chorioretinopathy, choroid, gonadal steroid hormones, prevalence, electroconvulsive therapy, epidural cortical stimulation, stromal cells, premenopause
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):5. https://doi.org/10.1167/iovs.65.8.5

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

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Jordan Loeliger; Romain Lhotte; Sahar Gelfman; Eli A. Stahl; Dominique Monnet; Valentin Clichet; Linda Imikirene; Souhila Kecili; Jean-Luc Taupin; Thierry Tabary; Jacques H. M. Cohen; Antoine P. Brézin
TAGS: alleles, disease susceptibility, hla-a antigens, homozygote, human leukocyte antigens, vitiliginous chorioretinitis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):47. https://doi.org/10.1167/iovs.65.13.47

Includes: Supplemental Content

Methods December 2024

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

PDF

Yukai Zhao; Luis Andres Lesmes; Michael Dorr; Zhong-Lin Lu
TAGS: carotid sinus syncope, churg-strauss syndrome, contrast sensitivity, inference, luminance, datasets
Trans. Vis. Sci. Tech.. 2024; 13(12):17. https://doi.org/10.1167/tvst.13.12.17

Includes: Supplemental Content

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

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Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Genetics June 2024

The LCHADD Mouse Model Recapitulates Early-Stage Chorioretinopathy in LCHADD Patients

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Shannon J. Babcock; Allison G. Curtis; Garen Gaston; Gabriela Elizondo; Melanie B. Gillingham; Renee C. Ryals
TAGS: mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):33. https://doi.org/10.1167/iovs.65.6.33

Includes: Supplemental Content

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Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population

Effects of a Hyperbaric Normoxic Environment on the Retina and Choroid

Elevated Plasma Complement Factors in CRB1 -Associated Inherited Retinal Dystrophies

OCT Angiography of Type 1 Macular Neovascularization in AMD: A Morphometric Evaluation

Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel

Clinical, Genetic, Imaging and Electrophysiological Findings in a Cohort of Patients With GUCA1A -Associated Retinopathy

Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment

Comprehensive Visualization of Choroidal Alterations in Thyroid Eye Disease With Ultra-Widefield OCT Angiography

Subthreshold Micropulse Laser Versus Oral Spironolactone in Chronic Central Serous Chorioretinopathy: A Quasi-Randomized Controlled Trial

Visual Performance and Predictive OCT Biomarkers in Epiretinal Membrane Assessment: Beyond Distance Visual Acuity

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

Topographical Quantification of Hyper-Reflective Foci May Predict the Development of Macular Atrophy in Patients With Neovascular Age-Related Macular Degeneration

A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

Differential Expression of Sex-Steroid Receptors in the Choroid Aligns With Central Serous Chorioretinopathy Sex Prevalence Across Different Ages

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

The LCHADD Mouse Model Recapitulates Early-Stage Chorioretinopathy in LCHADD Patients

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