Biochemistry and Molecular Biology

Showing 1 – 20 of 3930

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Immunology and Microbiology April 2025

RNA-Sequencing Reveals the Modulation of the NLRP3 Inflammasome by miR-223-3p in Extracellular Vesicles in Bacterial Endophthalmitis

PDF

Dhanwini Rudraprasad; Jayabalan Nirmal; Dilip Kumar Mishra; Joveeta Joseph
TAGS: bacterial endophthalmitis, endophthalmitis, micrornas, nlr family, pyrin domain-containing 3 protein, mice, rna, messenger, extracellular vesicles, infections, inflammasomes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):53. https://doi.org/10.1167/iovs.66.4.53

Includes: Supplemental Content

Cornea April 2025

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

PDF

Haiqi Xiao; Li Hu; Xiongshi Lin; Linchang Liu; Xing Dong; Liting Yang; Ying Liu; Zhichong Wang; Ying Tian; Shuangyong Wang
TAGS: pax6 transcription factor, soluble fms-like tyrosine kinase 1
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):52. https://doi.org/10.1167/iovs.66.4.52

Includes: Supplemental Content

Biochemistry and Molecular Biology April 2025

NMN Supplementation Inhibits Endothelial Cell ROS-Mediated Src/Pi3k/Akt Signaling Pathway to Protect High-Altitude Blood-Retinal Barrier

PDF

Siyuan Liu; Ning Du; Keke Ge; Jiayue Hu; Wenfang Zhang
TAGS: 1-phosphatidylinositol 3-kinase, endothelial cells, high altitude, hypoxia, cadherins, akt signaling pathway, mice, fluorescent antibody technique, evans blue stain, blood-retinal barrier
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):51. https://doi.org/10.1167/iovs.66.4.51

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology April 2025

The Influence of Changes in Microglia Development on the Plasticity of the Developing Visual Cortex Circuit in Juvenile Mice

PDF

Xuechun Wang; Kuan Li; Lingzhi Guo; Xinlong Liu; Yatu Guo; Wei Zhang
TAGS: mice, microglia, visual cortex, interneurons, neurons, small nuclear rna, child
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):45. https://doi.org/10.1167/iovs.66.4.45

Includes: Supplemental Content

Cornea April 2025

Antigen Presentation by Extracellular Vesicles in the Acute Phase of Corneal Transplantation

PDF

Toshiki Shimizu; Takahiko Hayashi; Junki Kurita; Kentaro Yuda; Nobuhisa Mizuki; Satoru Yamagami
TAGS: antigen processing and presentation, extracellular vesicles, keratoplasty, tissue transplants, cornea
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):38. https://doi.org/10.1167/iovs.66.4.38

Includes: Supplemental Content

Article April 2025

Interocular suppression in chromoluminance patterns measured with SSVEP

PDF

Alex A. Carter; Daniel H. Baker; Antony B. Morland; Abbie J. Lawton; Alex R. Wade
TAGS: color, electroencephalography, eye, harmonics, luminance, neurons, ocular dominance, retinal cone, spatial frequency, visual system
Journal of Vision. 2025; 25(4):6. https://doi.org/10.1167/jov.25.4.6

Cornea April 2025

KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway

PDF

Yuzhou Wang; Zhiqiang Xu; Linzhi Wei; Yang Lu; Yizhou Shi; Shiyu Wen; Xiujuan Lv; Kaiyan Huang; Fan Lu; Jia Qu; Liang Hu
TAGS: hmgb1 protein, mice, toll-like receptor 4, inflammation, dry eye syndromes, cornea
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):28. https://doi.org/10.1167/iovs.66.4.28

Includes: Supplemental Content

Biochemistry and Molecular Biology April 2025

Treatment of Pathological Lymphangiogenesis via Circular RNA-Mediated Cholesterol Metabolism Remodeling

PDF

Shuting Lu; Qian Liu; Fan Ye; Ziran Zhang; Lianjun Shi; Xiumiao Li; Wan Mu; Qin Jiang; Biao Yan
TAGS: cholesterol metabolism, lymphangiogenesis, lymphatic vessels, rna, cornea, sutures, circular rna, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):26. https://doi.org/10.1167/iovs.66.4.26

Includes: Supplemental Content

Cornea & External Disease April 2025

Causal Relationship Between Common Allergic Diseases and Keratoconus: A Two-Sample Mendelian Randomization Study

PDF

Xiru Yang; Xinyao Yu; Shan Gao; Pinghui Wei; Guoge Han
TAGS: extrinsic asthma, hypersensitivity, keratoconus, mendelian randomization analysis, atopic dermatitis, urticaria
Trans. Vis. Sci. Tech.. 2025; 14(4):14. https://doi.org/10.1167/tvst.14.4.14

Cornea & External Disease April 2025

Metabolic Biomarkers Mediate Allergic Conjunctivitis via Circulating Inflammatory Proteins: Evidence From a Mendelian Randomization Study

PDF

Xiang Cao; Zijiao Xu; Boyang Zhang; Qingyu Li; Zhixin Jiang; Xiaoyong Yuan
TAGS: allergic conjunctivitis, biological markers, mendelian randomization analysis, modified barium swallow, proteins
Trans. Vis. Sci. Tech.. 2025; 14(4):12. https://doi.org/10.1167/tvst.14.4.12

Includes: Supplemental Content

Retina April 2025

Fecal Microbial Profiles and Short-Chain Fatty Acid/Bile Acid Metabolomics in Patients With Age-Related Macular Degeneration: A Pilot Study

PDF

Zaid Parekh; Jason Xiao; Amir Mani; Quadis Evans; Christopher Phung; Hugo A. Barba; Bingqing Xie; Ashley M. Sidebottom; Anitha Sundararajan; Huaiying Lin; Ramanujam Ramaswamy; David Dao; Reem Gonnah; Madeleine Yehia; Seenu M. Hariprasad; Mark D'Souza; Dinanath Sulakhe; Eugene B. Chang; Dimitra Skondra
TAGS: age-related macular degeneration, bile acids, feces, metabolites, metabolomics, pilot projects, volatile fatty acids, cohort studies, microbiome, gastrointestinal microbiome
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):21. https://doi.org/10.1167/iovs.66.4.21

Includes: Supplemental Content

Immunology and Microbiology April 2025

Role of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

PDF

Min Seok Kim; Soo Hyun Choi; Hyun Young Park; Sun Young Jang; JaeSang Ko; Jae-woo Kim; Jin Sook Yoon
TAGS: body tissue, fibroblasts, pathogenesis, hyaluronan
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):20. https://doi.org/10.1167/iovs.66.4.20

Includes: Supplemental Content

Glaucoma April 2025

Effects of Verteporfin on Interstitial Fluid Flow-Induced Fibrotic Transdifferentiation of Human Tenon Fibroblasts

PDF

Janne Frömmichen; Emma Bungert; Jeanne Ströble; Moritz Gläser; Charlotte Gottwald; Kosovare Zeqiri; Thomas Reinhard; Jan Lübke; Günther Schlunck; Cornelius Jakob Wiedenmann
TAGS: fibroblasts, fibrosis, fluid flow, interstitial fluid, verteporfin, actins, cell transdifferentiation, connective tissue growth factor
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):17. https://doi.org/10.1167/iovs.66.4.17

Visual Neuroscience April 2025

Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis

PDF

Lili Chen; Zhonghao Yu; Senmiao Zhu; Shihan Song; Guanwen He; Zai-Long Chi; Wencan Wu
TAGS: astrocytes, extracellular vesicles, micrornas, optic nerve injuries, rna, messenger, homeostasis, phosphate-buffered saline, wounds and injuries, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):16. https://doi.org/10.1167/iovs.66.4.16

Includes: Supplemental Content

Biochemistry and Molecular Biology April 2025

Comparative Evaluation of Cigarette Smoke and a Heated Tobacco Product on Corneal Oxidative Stress in an Air/Liquid Interface Model

PDF

Sebastiano Giallongo; Francesco Bellia; Andrea Russo; Matteo Fallico; Riccardo Polosa; Niccolò Castellino; Antonio Longo; Rosalia Emma; Konstantinos Partsinevelos; Massimo Caruso; Arief S. Kartasasmita; Giuseppe Sferrazzo; Ignazio Alberto Barbagallo; Rosario Caltabiano; Giuseppe Broggi; Amer M. Alanazi; Giovanni Li Volti
TAGS: cigarette smoke, cornea, liquids, oxidative stress, tobacco, smoke
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):4. https://doi.org/10.1167/iovs.66.4.4

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks I: The role of fixational drift in the Vernier task

Fabian Coupette; David H. Brainard; Hannah E. Smithson; Daniel J. Read
TAGS: blurry vision, diffusion, eye, eye movement, medical history, motion, noise, perception, persistence, recovery of function
Journal of Vision. 2025; 25(5):8. https://doi.org/10.1167/jov.25.5.8

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

Gene Identification for Ocular Congenital Cranial Motor Neuron Disorders Using Human Sequencing, Zebrafish Screening, and Protein Binding Microarrays

PDF

Julie A. Jurgens; Paola M. Matos Ruiz; Jessica King; Emma E. Foster; Lindsay Berube; Wai-Man Chan; Brenda J. Barry; Raehoon Jeong; Elisabeth Rothman; Mary C. Whitman; Sarah MacKinnon; Cristina Rivera-Quiles; Brandon M. Pratt; Teresa Easterbrooks; Fiona M. Mensching; Silvio Alessandro Di Gioia; Lynn Pais; Eleina M. England; Teresa de Berardinis; Adriano Magli; Feray Koc; Kazuhide Asakawa; Koichi Kawakami; Anne O'Donnell-Luria; David G. Hunter; Caroline D. Robson; Martha L. Bulyk; Elizabeth C. Engle
TAGS: cranium, genes, motor neurons, protein binding, screening, zebrafish, transcription factor, candidate disease gene, pathogenicity
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):62. https://doi.org/10.1167/iovs.66.3.62

Includes: Supplemental Content

Retina March 2025

Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

PDF

Rajya L. Gurung; Charvi Nangia; Tengda Cai; Liesel M. FitzGerald; Bennet J. McComish; Ebony Liu; Georgia Kaidonis; Bronwyn Ridge; Alex W. Hewitt; Brendan Vote; Nitin Verma; Jamie E. Craig; Colin N. A. Palmer; Kathryn P. Burdon; Weihua Meng
TAGS: cohort studies, diabetes mellitus, genetics, genome-wide association study, macular disorders, meta-analysis, single nucleotide polymorphism, genotype determination, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):55. https://doi.org/10.1167/iovs.66.3.55

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2025

Epigenetic ALYREF/UHRF1/RHOB Axis in Corneal Wound Healing and Implications for Epithelial Tumorigenesis

PDF

Hua Zhang; Shuning Lan; Disuo Ren; Xiaoyan Chen; Yong Lin; Qiongjie Cao; Weiwei Xu; Jiao Wang; Peter Sol Reinach; Dongsheng Yan; Guangying Luo
TAGS: cornea, dna methylation, epigenetics, epithelium, genes, rna, tumorigenesis, wound healing, neoplasms, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):54. https://doi.org/10.1167/iovs.66.3.54

Includes: Supplemental Content

Cornea March 2025

The Spatial Transcriptomic Atlas of Human Limbus and Vital Niche Microenvironment Regulating the Fate of Limbal Epithelial Stem Cells

PDF

Shiding Li; Hao Sun; Fei Fang; Siyi Zhang; Junzhao Chen; Chunyi Shao; Yao Fu; Liangbo Chen
TAGS: body tissue, cell communication, cornea, epithelial stem cells, epithelium, fluorescent antibody technique, genes, rna, small cytoplasmic, transcriptomics, melanocytes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):52. https://doi.org/10.1167/iovs.66.3.52

Includes: Supplemental Content

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

RNA-Sequencing Reveals the Modulation of the NLRP3 Inflammasome by miR-223-3p in Extracellular Vesicles in Bacterial Endophthalmitis

Pax6 Directly Regulates the Raver2/sFlt-1 Expression in Corneal Epithelial Cells to Maintain the Cornea's Avascular Privilege

NMN Supplementation Inhibits Endothelial Cell ROS-Mediated Src/Pi3k/Akt Signaling Pathway to Protect High-Altitude Blood-Retinal Barrier

The Influence of Changes in Microglia Development on the Plasticity of the Developing Visual Cortex Circuit in Juvenile Mice

Antigen Presentation by Extracellular Vesicles in the Acute Phase of Corneal Transplantation

Interocular suppression in chromoluminance patterns measured with SSVEP

KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway

Treatment of Pathological Lymphangiogenesis via Circular RNA-Mediated Cholesterol Metabolism Remodeling

Causal Relationship Between Common Allergic Diseases and Keratoconus: A Two-Sample Mendelian Randomization Study

Metabolic Biomarkers Mediate Allergic Conjunctivitis via Circulating Inflammatory Proteins: Evidence From a Mendelian Randomization Study

Fecal Microbial Profiles and Short-Chain Fatty Acid/Bile Acid Metabolomics in Patients With Age-Related Macular Degeneration: A Pilot Study

Role of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

Effects of Verteporfin on Interstitial Fluid Flow-Induced Fibrotic Transdifferentiation of Human Tenon Fibroblasts

Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis

Comparative Evaluation of Cigarette Smoke and a Heated Tobacco Product on Corneal Oxidative Stress in an Air/Liquid Interface Model

Contributed Talks I: The role of fixational drift in the Vernier task

Gene Identification for Ocular Congenital Cranial Motor Neuron Disorders Using Human Sequencing, Zebrafish Screening, and Protein Binding Microarrays

Genome-Wide Association Study to Identify Genetic Variants Associated With Diabetic Maculopathy

Epigenetic ALYREF/UHRF1/RHOB Axis in Corneal Wound Healing and Implications for Epithelial Tumorigenesis

The Spatial Transcriptomic Atlas of Human Limbus and Vital Niche Microenvironment Regulating the Fate of Limbal Epithelial Stem Cells

This feature is available to authenticated users only.

Biochemistry and Molecular Biology

To View More...

You must be signed into an individual account to use this feature.