Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research January 2019

Longitudinal Changes in Spherical Equivalent Refractive Error Among Children With Preschool Myopia

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Yin Hu; Xiaohu Ding; Wen Long; Mingguang He; Xiao Yang
TAGS: child, preschools, refractive errors, myopia, refraction
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):154-160. doi: 10.1167/iovs.18-24862

Clinical and Epidemiologic Research January 2019

Preschool Children Exhibit Evident Compensatory Role of Internal Astigmatism in Distribution of Astigmatism: The Nanjing Eye Study

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Zijin Wang; Dan Huang; Xuejuan Chen; Hui Zhu; Qigang Sun; Yue Wang; Xiaohan Zhang; Yue Wang; Leili Zhai; Chenyang Wang; Hu Liu
TAGS: eye, astigmatism, preschool child
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):73-81. doi: 10.1167/iovs.18-24799

Clinical and Epidemiologic Research January 2019

Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

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Geoffrey S. Cohn; Dean Corbett; Abi Tenen; Minas Coroneo; James McAlister; Jennifer P. Craig; Trevor Gray; David Kent; Neil Murray; Con Petsoglou; Stephanie N. Baba; Edward J. Holland
TAGS: dry eye syndromes, tear production, safety, pilot projects
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):147-153. doi: 10.1167/iovs.18-23984

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2018

Clinically Relevant Immune-Cellular Metrics of Inflammation in Meibomian Gland Dysfunction

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Yureeda Qazi; Ahmad Kheirkhah; Caroline Blackie; Monique Trinidad; Candice Williams; Andrea Cruzat; Donald R. Korb; Pedram Hamrah
TAGS: conjunctiva, inflammation, pathophysiology, epithelium, signs and symptoms, eyelid, meibomian gland
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6111-6123. doi: 10.1167/iovs.18-25571

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2018

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

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Cecilia Chao; Lakshmi Akileswaran; Jessica N. Cooke Bailey; Mark Willcox; Russell Van Gelder; Carol Lakkis; Fiona Stapleton; Kathryn Richdale
TAGS: cytokine, environmental factors, contact lenses, genotype, cornea, interleukin-6, microbiome, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5752-5761. doi: 10.1167/iovs.18-24845

Includes: Supplemental Content

Genetics November 2018

Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population

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Akiko Miki; Yoichi Sakurada; Koji Tanaka; Kentaro Semba; Yoshinori Mitamura; Mitsuko Yuzawa; Atsushi Tajima; Masahiro Nakatochi; Ken Yamamoto; Keitaro Matsuo; Issei Imoto; Shigeru Honda
TAGS: disease susceptibility, single nucleotide polymorphism, central serous chorioretinopathy, genome-wide association study, japanese
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5542-5547. doi: 10.1167/iovs.18-25497

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2018

Possible Causes of Discordance in Refraction in Monozygotic Twins: Nearwork, Time Outdoors and Stochastic Variation

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Xiaohu Ding; Yin Hu; Xinxing Guo; Xiaobo Guo; Ian Morgan; Mingguang He
TAGS: environmental factors, questionnaires, twins, monozygotic twins, eye, refraction
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5349-5354. doi: 10.1167/iovs.18-24526

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2018

Prevalence of and Risk Factors for Diabetic Retinopathy in a Rural Chinese Population: The Yangxi Eye Study

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Guangming Jin; Wei Xiao; Xiaohu Ding; Xiao Xu; Lei An; Nathan Congdon; Jialiang Zhao; Mingguang He
TAGS: diabetes mellitus, diabetic retinopathy, china, risk factors, eye, prevalence, chinese (other dialects), chinese people
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5067-5073. doi: 10.1167/iovs.18-24280

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2018

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

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Chan-Wei Nien; Chia-Yi Lee; Shih-Chun Chao; Hung-Jui Hsu; Jing-Yang Huang; Chao-Bin Yeh; Hung-Chi Chen; Chi-Chin Sun; Hung-Yu Lin; Shun-Fa Yang
TAGS: cohort studies, uveitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5053-5059. doi: 10.1167/iovs.18-25039

Retina October 2018

Location of Ocular Tessellations in Japanese: Population-Based Kumejima Study

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Takehiro Yamashita; Aiko Iwase; Yuya Kii; Hiroshi Sakai; Hiroto Terasaki; Taiji Sakamoto; Makoto Araie
TAGS: cohort studies, eye, nose, fundus photography, japanese
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4963-4967. doi: 10.1167/iovs.18-25007

Clinical and Epidemiologic Research October 2018

Distribution and Severity of Myopic Maculopathy Among Highly Myopic Eyes

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Ou Xiao; Xinxing Guo; Decai Wang; Monica Jong; Pei Ying Lee; Linxing Chen; Ian G. Morgan; Padmaja Sankaridurg; Mingguang He
TAGS: eye, macular disorders
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4880-4885. doi: 10.1167/iovs.18-24471

Clinical and Epidemiologic Research October 2018

Dim Light Exposure and Myopia in Children

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Erica G. Landis; Victoria Yang; Dillon M. Brown; Machelle T. Pardue; Scott A. Read
TAGS: child, myopia, light exposure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4804-4811. doi: 10.1167/iovs.18-24415

Includes: Supplemental Content

Cornea September 2018

CTG18.1 Expansion is the Best Classifier of Late-Onset Fuchs' Corneal Dystrophy Among 10 Biomarkers in a Cohort From the European Part of Russia

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Liubov O. Skorodumova; Alexandra V. Belodedova; Olga P. Antonova; Elena I. Sharova; Tatiana A. Akopian; Oksana V. Selezneva; Elena S. Kostryukova; Boris E. Malyugin
TAGS: alleles, biological markers, cohort studies, hereditary corneal dystrophy, dna, genes, russia, genotype determination
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4748-4754. doi: 10.1167/iovs.18-24590

Clinical and Epidemiologic Research September 2018

Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract

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Ava Grace Tan; Annette Kifley; Elizabeth G. Holliday; Barbara E. K. Klein; Sudha K. Iyengar; Kristine E. Lee; Gyungah R. Jun; Robert G. Cumming; Wanting Zhao; Tien Yin Wong; Ching-Yu Cheng; Paul Mitchell; Jie Jin Wang
TAGS: polymorphism, aldehyde reductase, single nucleotide polymorphism, fasting blood glucose measurement, blood glucose, cortical cataract
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4755-4762. doi: 10.1167/iovs.18-24353

Clinical and Epidemiologic Research September 2018

Refractive Errors in University Students in Central China: The Anyang University Students Eye Study

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Shifei Wei; Yunyun Sun; Shiming Li; Jianping Hu; Xiaohui Yang; Caixia Lin; Kai Cao; Jialing Du; Jiyuan Guo; He Li; Ningli Wang
TAGS: china, myopia, refractive errors, student, eye, prevalence, cycloplegics, college students
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4691-4700. doi: 10.1167/iovs.18-24363

Clinical and Epidemiologic Research September 2018

Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore

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Yee-Ling Wong; Charumathi Sabanayagam; Yang Ding; Chee-Wai Wong; Anna Chwee-Hong Yeo; Yin-Bun Cheung; Gemmy Cheung; Audrey Chia; Kyoko Ohno-Matsui; Tien-Yin Wong; Jie Jin Wang; Ching-Yu Cheng; Quan V. Hoang; Ecosse Lamoureux; Seang-Mei Saw
TAGS: adult, eye diseases, myopia, risk factors, singapore, vision, visual impairment, eye, prevalence, fundus photography, myopic macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4603-4613. doi: 10.1167/iovs.18-24032

Clinical and Epidemiologic Research September 2018

Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study

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Samantha Bomotti; Bryan Lau; Barbara E. K. Klein; Kristine E. Lee; Ronald Klein; Priya Duggal; Alison P. Klein
TAGS: cohort studies, eye, refraction, cataract, nuclear
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4518-4524. doi: 10.1167/iovs.18-23914

Clinical and Epidemiologic Research August 2018

The EYE-MI Pilot Study: A Prospective Acute Coronary Syndrome Cohort Evaluated With Retinal Optical Coherence Tomography Angiography

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Louis Arnould; Charles Guenancia; Arthur Azemar; Guillaume Alan; Stéphane Pitois; Florence Bichat; Marianne Zeller; Pierre-Henry Gabrielle; Alain M. Bron; Catherine Creuzot-Garcher; Yves Cottin
TAGS: acute coronary syndromes, angiogram, left ventricular ejection fraction, cardiovascular disease risk factors, cohort studies, eye, optical coherence tomography, retinal vasculature, pilot projects
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4299-4306. doi: 10.1167/iovs.18-24090

Includes: Supplemental Content

Genetics August 2018

Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect

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Sherin Shaaban; Sarah MacKinnon; Caroline Andrews; Sandra E. Staffieri; Gail D. E. Maconachie; Wai-Man Chan; Mary C. Whitman; Sarah U. Morton; Seyhan Yazar; Stuart MacGregor; James E. Elder; Elias I. Traboulsi; Irene Gottlob; Alex W. Hewitt; Strabismus Genetics Research Consortium; David G. Hunter; David A. Mackey; Elizabeth C. Engle
TAGS: meta-analysis, esotropia, cohort studies, disease susceptibility, genome, parent, single nucleotide polymorphism, strabismus, genetics, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4054-4064. doi: 10.1167/iovs.18-24082

Includes: Supplemental Content

Glaucoma August 2018

Change of β-Zone Parapapillary Atrophy During Axial Elongation: Boramae Myopia Cohort Study Report 3

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Kyoung Min Lee; Ho-Kyung Choung; Martha Kim; Sohee Oh; Seok Hwan Kim
TAGS: glaucoma, atrophy, cohort studies, myopia, optic disk, eye, hypertrophy, sclera, trunk structure, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4020-4030. doi: 10.1167/iovs.18-24775

Includes: Supplemental Content

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Longitudinal Changes in Spherical Equivalent Refractive Error Among Children With Preschool Myopia

Preschool Children Exhibit Evident Compensatory Role of Internal Astigmatism in Distribution of Astigmatism: The Nanjing Eye Study

Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

Clinically Relevant Immune-Cellular Metrics of Inflammation in Meibomian Gland Dysfunction

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population

Possible Causes of Discordance in Refraction in Monozygotic Twins: Nearwork, Time Outdoors and Stochastic Variation

Prevalence of and Risk Factors for Diabetic Retinopathy in a Rural Chinese Population: The Yangxi Eye Study

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

Location of Ocular Tessellations in Japanese: Population-Based Kumejima Study

Distribution and Severity of Myopic Maculopathy Among Highly Myopic Eyes

Dim Light Exposure and Myopia in Children

CTG18.1 Expansion is the Best Classifier of Late-Onset Fuchs' Corneal Dystrophy Among 10 Biomarkers in a Cohort From the European Part of Russia

Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract

Refractive Errors in University Students in Central China: The Anyang University Students Eye Study

Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore

Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study

The EYE-MI Pilot Study: A Prospective Acute Coronary Syndrome Cohort Evaluated With Retinal Optical Coherence Tomography Angiography

Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect

Change of β-Zone Parapapillary Atrophy During Axial Elongation: Boramae Myopia Cohort Study Report 3

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