Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research April 2019

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

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Caroline Brandl; Christiane Brücklmayer; Felix Günther; Martina E. Zimmermann; Helmut Küchenhoff; Horst Helbig; Bernhard H. F. Weber; Iris M. Heid; Klaus J. Stark
TAGS: sample size, biological response modifiers, color, photoreceptors, reference values, software, diagnostic imaging, eye, age-related macular degeneration, reliability, german, spectral-domain optical coherence tomography, surveys
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1581-1594. doi: 10.1167/iovs.18-25332

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2019

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

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Emily E. Brown; Jacob D. Ball; Zhaoyi Chen; Gibran S. Khurshid; Mattia Prosperi; John D. Ash
TAGS: metformin, age-related macular degeneration, antidiabetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1470-1477. doi: 10.1167/iovs.18-26422

Clinical and Epidemiologic Research April 2019

Small Hard Macular Drusen and Associations in 11- to 12-Year-Old Children in the Copenhagen Child Cohort 2000 Eye Study

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Inger Christine Munch; Xiao Qiang Li; Shaista Sumbal Mulk Ahmad; Else Marie Olsen; Anne Mette Skovgaard; Michael Larsen
TAGS: drusen, child, cohort studies, retinal drusen, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1454-1460. doi: 10.1167/iovs.18-25877

Clinical and Epidemiologic Research April 2019

Serum 25-Hydroxyvitamin D Concentrations and Incidence of Age-Related Macular Degeneration: The Atherosclerosis Risk in Communities Study

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Amy E. Millen; Jing Nie; Julie A. Mares; Pamela L. Lutsey; Michael J. LaMonte; Stacy M. Meuer; Michelle W. Sahli; Christopher A. Andrews; Barbara E. K. Klein; Ronald Klein
TAGS: drusen, incidence, macular degeneration, age-related macular degeneration, vitamin d, aric trial, 25-hydroxyvitamin d
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1362-1371. doi: 10.1167/iovs.18-25945

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2019

Refractive Change and Incidence of Myopia Among A Group of Highly Selected Senior High School Students in China: A Prospective Study in An Aviation Cadet Prerecruitment Class

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Lu Yao; Lin-song Qi; Xue-feng Wang; Qing Tian; Qing-hong Yang; Teng-yun Wu; Yao-ming Chang; Zhi-kang Zou
TAGS: aviation, child, myopia, student, incidence, high schools, prospective studies, china
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1344-1352. doi: 10.1167/iovs.17-23506

Clinical and Epidemiologic Research March 2019

Progression of Myopic Maculopathy in Highly Myopic Chinese Eyes

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Zhixi Li; Ran Liu; Ou Xiao; Xinxing Guo; Decai Wang; Jian Zhang; Jason James Ha; Jonathan Tak Loong Lee; Peiying Lee; Monica Jong; Padmaja Sankaridurg; Kyoko Ohno-Matsui; Mingguang He
TAGS: eye, chinese people, macular disorders, chinese (other dialects)
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1096-1104. doi: 10.1167/iovs.18-25800

Article March 2019

Perceptual reversals in binocular rivalry: Improved detection from OKN

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Stepan Aleshin; Gergő Ziman; Ilona Kovács; Jochen Braun
TAGS: motion, perception, pursuit, smooth, artifacts, eye, velocity, precision
Journal of Vision. 2019; 19(3):5. doi: 10.1167/19.3.5

Clinical and Epidemiologic Research February 2019

Intraocular Pressure in General and Diabetic Populations From Southern China: the Dongguan Eye Study

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Ying Cui; Xiaohong Yang; Guanrong Zhang; Haike Guo; Min Zhang; Lixin Zhang; Jin Zeng; Qingyang Liu; Liang Zhang; Qianli Meng
TAGS: diabetes mellitus, china, risk factors, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):761-769. doi: 10.1167/iovs.18-25247

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2019

Longitudinal Changes in Spherical Equivalent Refractive Error Among Children With Preschool Myopia

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Yin Hu; Xiaohu Ding; Wen Long; Mingguang He; Xiao Yang
TAGS: child, preschools, refractive errors, myopia, refraction
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):154-160. doi: 10.1167/iovs.18-24862

Clinical and Epidemiologic Research January 2019

Preschool Children Exhibit Evident Compensatory Role of Internal Astigmatism in Distribution of Astigmatism: The Nanjing Eye Study

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Zijin Wang; Dan Huang; Xuejuan Chen; Hui Zhu; Qigang Sun; Yue Wang; Xiaohan Zhang; Yue Wang; Leili Zhai; Chenyang Wang; Hu Liu
TAGS: eye, astigmatism, preschool child
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):73-81. doi: 10.1167/iovs.18-24799

Clinical and Epidemiologic Research January 2019

Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

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Geoffrey S. Cohn; Dean Corbett; Abi Tenen; Minas Coroneo; James McAlister; Jennifer P. Craig; Trevor Gray; David Kent; Neil Murray; Con Petsoglou; Stephanie N. Baba; Edward J. Holland
TAGS: dry eye syndromes, tear production, safety, pilot projects
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):147-153. doi: 10.1167/iovs.18-23984

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2018

Clinically Relevant Immune-Cellular Metrics of Inflammation in Meibomian Gland Dysfunction

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Yureeda Qazi; Ahmad Kheirkhah; Caroline Blackie; Monique Trinidad; Candice Williams; Andrea Cruzat; Donald R. Korb; Pedram Hamrah
TAGS: conjunctiva, inflammation, pathophysiology, epithelium, signs and symptoms, eyelid, meibomian gland
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6111-6123. doi: 10.1167/iovs.18-25571

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2018

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

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Cecilia Chao; Lakshmi Akileswaran; Jessica N. Cooke Bailey; Mark Willcox; Russell Van Gelder; Carol Lakkis; Fiona Stapleton; Kathryn Richdale
TAGS: cytokine, environmental factors, contact lenses, genotype, cornea, interleukin-6, microbiome, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5752-5761. doi: 10.1167/iovs.18-24845

Includes: Supplemental Content

Genetics November 2018

Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population

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Akiko Miki; Yoichi Sakurada; Koji Tanaka; Kentaro Semba; Yoshinori Mitamura; Mitsuko Yuzawa; Atsushi Tajima; Masahiro Nakatochi; Ken Yamamoto; Keitaro Matsuo; Issei Imoto; Shigeru Honda
TAGS: disease susceptibility, single nucleotide polymorphism, central serous chorioretinopathy, genome-wide association study, japanese
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5542-5547. doi: 10.1167/iovs.18-25497

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2018

Possible Causes of Discordance in Refraction in Monozygotic Twins: Nearwork, Time Outdoors and Stochastic Variation

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Xiaohu Ding; Yin Hu; Xinxing Guo; Xiaobo Guo; Ian Morgan; Mingguang He
TAGS: environmental factors, questionnaires, twins, monozygotic twins, eye, refraction
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5349-5354. doi: 10.1167/iovs.18-24526

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2018

Prevalence of and Risk Factors for Diabetic Retinopathy in a Rural Chinese Population: The Yangxi Eye Study

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Guangming Jin; Wei Xiao; Xiaohu Ding; Xiao Xu; Lei An; Nathan Congdon; Jialiang Zhao; Mingguang He
TAGS: diabetes mellitus, diabetic retinopathy, china, risk factors, eye, prevalence, chinese (other dialects), chinese people
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5067-5073. doi: 10.1167/iovs.18-24280

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2018

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

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Chan-Wei Nien; Chia-Yi Lee; Shih-Chun Chao; Hung-Jui Hsu; Jing-Yang Huang; Chao-Bin Yeh; Hung-Chi Chen; Chi-Chin Sun; Hung-Yu Lin; Shun-Fa Yang
TAGS: cohort studies, uveitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5053-5059. doi: 10.1167/iovs.18-25039

Retina October 2018

Location of Ocular Tessellations in Japanese: Population-Based Kumejima Study

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Takehiro Yamashita; Aiko Iwase; Yuya Kii; Hiroshi Sakai; Hiroto Terasaki; Taiji Sakamoto; Makoto Araie
TAGS: cohort studies, eye, nose, fundus photography, japanese
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4963-4967. doi: 10.1167/iovs.18-25007

Clinical and Epidemiologic Research October 2018

Distribution and Severity of Myopic Maculopathy Among Highly Myopic Eyes

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Ou Xiao; Xinxing Guo; Decai Wang; Monica Jong; Pei Ying Lee; Linxing Chen; Ian G. Morgan; Padmaja Sankaridurg; Mingguang He
TAGS: eye, macular disorders
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4880-4885. doi: 10.1167/iovs.18-24471

Clinical and Epidemiologic Research October 2018

Dim Light Exposure and Myopia in Children

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Erica G. Landis; Victoria Yang; Dillon M. Brown; Machelle T. Pardue; Scott A. Read
TAGS: child, myopia, light exposure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4804-4811. doi: 10.1167/iovs.18-24415

Includes: Supplemental Content

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Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

Small Hard Macular Drusen and Associations in 11- to 12-Year-Old Children in the Copenhagen Child Cohort 2000 Eye Study

Serum 25-Hydroxyvitamin D Concentrations and Incidence of Age-Related Macular Degeneration: The Atherosclerosis Risk in Communities Study

Refractive Change and Incidence of Myopia Among A Group of Highly Selected Senior High School Students in China: A Prospective Study in An Aviation Cadet Prerecruitment Class

Progression of Myopic Maculopathy in Highly Myopic Chinese Eyes

Perceptual reversals in binocular rivalry: Improved detection from OKN

Intraocular Pressure in General and Diabetic Populations From Southern China: the Dongguan Eye Study

Longitudinal Changes in Spherical Equivalent Refractive Error Among Children With Preschool Myopia

Preschool Children Exhibit Evident Compensatory Role of Internal Astigmatism in Distribution of Astigmatism: The Nanjing Eye Study

Randomized, Controlled, Double-Masked, Multicenter, Pilot Study Evaluating Safety and Efficacy of Intranasal Neurostimulation for Dry Eye Disease

Clinically Relevant Immune-Cellular Metrics of Inflammation in Meibomian Gland Dysfunction

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population

Possible Causes of Discordance in Refraction in Monozygotic Twins: Nearwork, Time Outdoors and Stochastic Variation

Prevalence of and Risk Factors for Diabetic Retinopathy in a Rural Chinese Population: The Yangxi Eye Study

Effect of Uveitis on the Development of Keratopathy: A Population-Based Cohort Study

Location of Ocular Tessellations in Japanese: Population-Based Kumejima Study

Distribution and Severity of Myopic Maculopathy Among Highly Myopic Eyes

Dim Light Exposure and Myopia in Children

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