Cornea

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Cornea & External Disease August 2022

Accurate In Vivo Bowman's Thickness Measurement Using Mirau Ultrahigh Axial Resolution Line Field Optical Coherence Tomography

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Samuel Lawman; Sharon Mason; Stephen B. Kaye; Yao-Chun Shen; Yalin Zheng
TAGS: bowman's layer, cornea, diagnostic imaging, epithelium, optical coherence tomography, spatial vectors, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2022; 11(8):6. doi: https://doi.org/10.1167/tvst.11.8.6

Cornea & External Disease August 2022

Changes in Rat Scleral Collagen Structure Induced by UVA–Riboflavin Crosslinking at Various Tissue Depths in Whole Globe Versus Scleral Patch

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Yuan Miao; Juan Liu; Sruti S. Akella; Jessie Wang; Shaowei Li; Roy S. Chuck; Cheng Zhang
TAGS: body tissue, collagen, corneal collagen cross-linking, eye, riboflavin, sclera, ultraviolet a radiation, collagen fiber
Trans. Vis. Sci. Tech.. 2022; 11(8):2. doi: https://doi.org/10.1167/tvst.11.8.2

Clinical and Epidemiologic Research July 2022

Foveal Curvature and Its Associations in UK Biobank Participants

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Abraham Olvera-Barrios; Yuka Kihara; Yue Wu; Alasdair N. Warwick; Philipp L. Müller; Katie M. Williams; Alicja R. Rudnicka; Christopher G. Owen; Aaron Y. Lee; Catherine Egan; Adnan Tufail; on behalf of the UK Biobank Eyes and Vision Consortium
TAGS: biobanks, ethnic group, income, eye, astigmatism, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):26. doi: https://doi.org/10.1167/iovs.63.8.26

Includes: Supplemental Content

Cornea & External Disease July 2022

Ocular Surface Immune Cell Profiles in Contact Lens–Induced Discomfort

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Archana Padmanabhan Nair; Swaminathan Sethu; Harsha Nagaraj; Vijay Kumar; Sriharsha Nagaraj; Zohra Fadli; Charles Scales; Mike Chemaly; Xiao-Yu Song; Arkasubhra Ghosh; Bailin Liang
TAGS: contact lenses, lens (device), lens, crystalline, ocular surfaces, cytology
Trans. Vis. Sci. Tech.. 2022; 11(7):16. doi: https://doi.org/10.1167/tvst.11.7.16

Includes: Supplemental Content

Cornea July 2022

Labial Mucosa Stem Cells: Isolation, Characterization, and Their Potential for Corneal Epithelial Reconstruction

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Kirill E. Zhurenkov; Elga I. Alexander-Sinkler; Ilya O. Gavrilyik; Natalia M. Yartseva; Svetlana A. Aleksandrova; Tatiana V. Mashel; Julia I. Khorolskaya; Miralda I. Blinova; Alexei N. Kulikov; Sergei V. Churashov; Valery F. Chernysh; Natalia A. Mikhailova
TAGS: cornea, epithelium, lip, mucous membrane, oryctolagus cuniculus, patient isolation, reconstructive surgical procedures, social isolation, stem cells, tissue transplants
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):16. doi: https://doi.org/10.1167/iovs.63.8.16

Includes: Supplemental Content

Cornea & External Disease July 2022

Heritability of Corneal Parameters in Nuclear Families With Keratoconus

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Yawen Wang; Liyan Xu; Shaopei Wang; Kaili Yang; Yuwei Gu; Qi Fan; Qing Wang; Meng Zhu; Kai Guo; Chenjiu Pang; Shengwei Ren; Dongqing Zhao
TAGS: cornea, keratoconus, nuclear family
Trans. Vis. Sci. Tech.. 2022; 11(7):13. doi: https://doi.org/10.1167/tvst.11.7.13

Includes: Supplemental Content

Cornea July 2022

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium

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Jing Xu; Peng Chen; Xiaoyu Luan; Xinying Yuan; Susu Wei; Yaxin Li; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cicatrix, cornea, fibrosis, macrophages, nlr family, pyrin domain-containing 3 protein, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):15. doi: https://doi.org/10.1167/iovs.63.8.15

Includes: Supplemental Content

Cornea & External Disease July 2022

In Vivo Determination of the Human Corneal Elastic Modulus Using Vibrational Optical Coherence Tomography

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Marcos A. Crespo; Hiram J. Jimenez; Tanmay Deshmukh; Jose S. Pulido; Ahmed Saeed Saad; Frederick H. Silver; Dominick A. Benedetto; Christopher J. Rapuano; Zeba A. Syed
TAGS: cornea, optical coherence tomography, anesthesia, topical
Trans. Vis. Sci. Tech.. 2022; 11(7):11. doi: https://doi.org/10.1167/tvst.11.7.11

Includes: Supplemental Content

Cornea & External Disease July 2022

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury

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Lycia Pedral Sampaio; Guilherme S. L. Hilgert; Thomas Michael Shiju; Marcony R. Santhiago; Steven E. Wilson
TAGS: adrenal corticosteroids, alkalies, burns, cicatrix, cornea, fibrosis, glucocorticoids, losartan, mineralocorticoids, myofibroblasts
Trans. Vis. Sci. Tech.. 2022; 11(7):9. doi: https://doi.org/10.1167/tvst.11.7.9

Includes: Supplemental Content

Cornea July 2022

Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas

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Tanja Stachon; Mahsa Nastaranpour; Berthold Seitz; Eckart Meese; Lorenz Latta; Suphi Taneri; Navid Ardjomand; Nóra Szentmáry; Nicole Ludwig
TAGS: cornea, epithelium, micrornas, rna, messenger, keratoconus, body tissue, regulation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):7. doi: https://doi.org/10.1167/iovs.63.8.7

Includes: Supplemental Content

Cornea & External Disease July 2022

Virulence Genes of Staphylococcus aureus Associated With Keratitis, Conjunctivitis, and Contact Lens–Associated Inflammation

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Madeeha Afzal; Ajay Kumar Vijay; Fiona Stapleton; Mark Willcox
TAGS: conjunctivitis, contact lenses, genes, inflammation, keratitis, virulence, staphylococcus aureus, infections, virulence factors
Trans. Vis. Sci. Tech.. 2022; 11(7):5. doi: https://doi.org/10.1167/tvst.11.7.5

Includes: Supplemental Content

Cornea July 2022

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

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Hsiao-Sang Chu; Cornelia Peterson; Xitiz Chamling; Cynthia Berlinicke; Donald Zack; Albert S. Jun; James Foster
TAGS: agonists, cell lines, cell motility, corneal epithelial cells, corneal epithelium, cyclophosphamide, doxorubicin, prednisone, and vincristine, cytokine, regulation, stress response, cornea
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):1. doi: https://doi.org/10.1167/iovs.63.8.1

Includes: Supplemental Content

Articles June 2022

Healing Ability of Central Corneal Epithelium in Rabbit Ocular Surface Injury Models

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Wang Zhang; Xihong Lan; Jin Zhu; Canwei Zhang; Ying Huang; Kunlun Mo; Jieying Tan; Huizhen Guo; Huaxing Huang; Mingsen Li; Hong Ouyang; Li Wang
TAGS: chronic exertional compartment syndrome, corneal epithelium, ocular surfaces, oryctolagus cuniculus, wound healing, wounds and injuries, genes, cornea
Trans. Vis. Sci. Tech.. 2022; 11(6):28. doi: https://doi.org/10.1167/tvst.11.6.28

Includes: Supplemental Content

Articles June 2022

Development of an In Situ Printing System With Human Platelet Lysate-Based Bio-Adhesive to Treat Corneal Perforations

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Jingjing You; Hannah Frazer; Sepidar Sayyar; Zhi Chen; Xiao Liu; Adam Taylor; Benjamin Filippi; Stephen Beirne; Innes Wise; Constantinos Petsoglou; Chris Hodge; Gordon Wallace; Gerard Sutton
TAGS: adhesives, perforation of cornea, printing, lysate, cornea, blood platelets
Trans. Vis. Sci. Tech.. 2022; 11(6):26. doi: https://doi.org/10.1167/tvst.11.6.26

Includes: Multimedia, Supplemental Content

Articles June 2022

Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning

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Md Asif Khan Setu; Stefan Schmidt; Gwen Musial; Michael E. Stern; Philipp Steven
TAGS: cornea, datasets, deep learning, dendritic cells, finnish congenital nephrotic syndrome, microscopy, confocal, neurons, nerve fibers, craniofrontonasal dysplasia
Trans. Vis. Sci. Tech.. 2022; 11(6):24. doi: https://doi.org/10.1167/tvst.11.6.24

Includes: Supplemental Content

Articles June 2022

Corneal Lenticule Creation Using a New Solid-State Femtosecond Laser Measured by Spectral Domain OCT in a Porcine Eye Model

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Christoph Lwowski; Anna Voigt; Karel Van Keer; Thomas Kohnen
TAGS: cornea, eye, femtosecond pulsed lasers, solids, spectral domain-optical coherence tomography, suidae, lasers
Trans. Vis. Sci. Tech.. 2022; 11(6):20. doi: https://doi.org/10.1167/tvst.11.6.20

Biochemistry and Molecular Biology June 2022

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

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Lili Li; Kimberly J. Jasmer; Jean M. Camden; Lucas T. Woods; Adam L. Martin; Yong Yang; Maria Layton; Michael J. Petris; Olga J. Baker; Gary A. Weisman; Carisa K. Petris
TAGS: mice, dry eye syndromes, sjogren's syndrome
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):18. doi: https://doi.org/10.1167/iovs.63.6.18

Includes: Supplemental Content

Cornea June 2022

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

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Yinting Song; Haokun Zhang; Yanfang Zhu; Xiao Zhao; Yi Lei; Wei Zhou; Jinguo Yu; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: covid-19, infections, inflammation, muramidase, proteins, severe acute respiratory syndrome, corneal epithelial cells, sars-cov-2, coronavirus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):16. doi: https://doi.org/10.1167/iovs.63.6.16

Articles June 2022

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

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Yanzhi Zhao; Hongwei Yang; Yingjie Li; Yongbo Wang; Xiao Han; Yirui Zhu; Yubao Zhang; Guofu Huang
TAGS: cornea, elasticity imaging techniques, keratoconus, acoustics, optics, radiation, elasticity
Trans. Vis. Sci. Tech.. 2022; 11(6):4. doi: https://doi.org/10.1167/tvst.11.6.4

Cornea June 2022

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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Chaoqun Yu; Peng Chen; Jing Xu; Susu Wei; Qilong Cao; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cornea, corneal epithelium, dendritic cells, dry eye syndromes, mice, netrin-1, regulation, antibodies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):1. doi: https://doi.org/10.1167/iovs.63.6.1

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Accurate In Vivo Bowman's Thickness Measurement Using Mirau Ultrahigh Axial Resolution Line Field Optical Coherence Tomography

Changes in Rat Scleral Collagen Structure Induced by UVA–Riboflavin Crosslinking at Various Tissue Depths in Whole Globe Versus Scleral Patch

Foveal Curvature and Its Associations in UK Biobank Participants

Ocular Surface Immune Cell Profiles in Contact Lens–Induced Discomfort

Labial Mucosa Stem Cells: Isolation, Characterization, and Their Potential for Corneal Epithelial Reconstruction

Heritability of Corneal Parameters in Nuclear Families With Keratoconus

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium

In Vivo Determination of the Human Corneal Elastic Modulus Using Vibrational Optical Coherence Tomography

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury

Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas

Virulence Genes of Staphylococcus aureus Associated With Keratitis, Conjunctivitis, and Contact Lens–Associated Inflammation

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production

Healing Ability of Central Corneal Epithelium in Rabbit Ocular Surface Injury Models

Development of an In Situ Printing System With Human Platelet Lysate-Based Bio-Adhesive to Treat Corneal Perforations

Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning

Corneal Lenticule Creation Using a New Solid-State Femtosecond Laser Measured by Spectral Domain OCT in a Porcine Eye Model

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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