Cornea

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Cornea March 2023

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mouse Corneal Epithelial Cells

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Zhao-Jing Lu; Jin-Guo Ye; Dong-Liang Wang; Meng-Ke Li; Qi-Kai Zhang; Zhong Liu; Yan-Jing Huang; Cai-Neng Pan; Yu-Heng Lin; Zhuo-Xing Shi; Ying-Feng Zheng
TAGS: corneal epithelial cells, corneal epithelium, genes, mice, rna, small cytoplasmic, atac trial, cornea, rna-seq, chromatin
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):30. doi: https://doi.org/10.1167/iovs.64.3.30

Includes: Supplemental Content

Cornea & External Disease March 2023

Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study

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Mitchell A. Kirby; Gabriel Regnault; Ivan Pelivanov; Matthew O'Donnell; Ruikang K. Wang; Tueng T. Shen
TAGS: acoustics, cornea, elasticity imaging techniques, microbiology procedures, oryctolagus cuniculus, elasticity, optics, intraocular pressure
Trans. Vis. Sci. Tech.. 2023; 12(3):15. doi: https://doi.org/10.1167/tvst.12.3.15

Includes: Supplemental Content

Cornea & External Disease March 2023

Agreement of Total Keratometry and Posterior Keratometry Among IOLMaster 700, CASIA2, and Pentacam

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Aixia Jin; Xiaotong Han; Jiaqing Zhang; Xiaozhang Qiu; Yifan Zhang; Bo Qu; Xuhua Tan; Lixia Luo
TAGS: astigmatism, keratometry
Trans. Vis. Sci. Tech.. 2023; 12(3):13. doi: https://doi.org/10.1167/tvst.12.3.13

Includes: Supplemental Content

Refractive Intervention March 2023

Corneal Biomechanics After SMILE, Femtosecond-Assisted LASIK, and Photorefractive Keratectomy: A Matched Comparison Study

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Hassan Hashemi; Cynthia J. Roberts; Ahmed Elsheikh; Shiva Mehravaran; Parsa Panahi; Soheila Asgari
TAGS: biomechanics, comparative study research, cornea, keratectomy, keratomileusis, laser in situ, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2023; 12(3):12. doi: https://doi.org/10.1167/tvst.12.3.12

Cornea March 2023

Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

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Yu Chen; Jiheng Pu; Xinda Li; Lili Lian; Chaoxiang Ge; Zuimeng Liu; Weizhuo Wang; Ling Hou; Wei Chen; Jinyang Li
TAGS: corneal epithelium, dry eye syndromes, lacrimal gland, mice, dna, immunohistochemistry, cornea, interleukin-18
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):26. doi: https://doi.org/10.1167/iovs.64.3.26

Includes: Supplemental Content

Cornea & External Disease March 2023

Topical Ocular TRPV1 Antagonist SAF312 (Libvatrep) for Postoperative Pain After Photorefractive Keratectomy

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Vance Thompson; Majid Moshirfar; Thomas Clinch; Stephen Scoper; Steven H. Linn; Avery McIntosh; Yifang Li; Matt Eaton; Michael Ferriere; Kalliopi Stasi
TAGS: keratectomy, pain, postoperative pain, transient receptor potential v1 antagonists, eye, surrogate endpoints
Trans. Vis. Sci. Tech.. 2023; 12(3):7. doi: https://doi.org/10.1167/tvst.12.3.7

Includes: Supplemental Content

Cornea March 2023

Overactivation of Norepinephrine–β2-Adrenergic Receptor Axis Promotes Corneal Neovascularization

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Qiaoqiao Dong; Benxiang Qi; Bin Zhang; Xiaoyun Zhuang; Shijiu Chen; Qingjun Zhou; Bi Ning Zhang; Suxia Li
TAGS: choroidal neovascularization, cornea, corneal neovascularization, mice, norepinephrine, sutures, fibroblast growth factor 2, alkalies
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):20. doi: https://doi.org/10.1167/iovs.64.3.20

Includes: Supplemental Content

Cornea March 2023

Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty

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Ruixing Liu; Jingguo Li; Zhihua Guo; Dandan Chu; Chengcheng Li; Liuqi Shi; Junjie Zhang; Lei Zhu; Zhanrong Li
TAGS: cornea, descemet stripping endothelial keratoplasty, fibrosis, signal transduction, proteins, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):9. doi: https://doi.org/10.1167/iovs.64.3.9

Immunology and Microbiology March 2023

Time-Course Transcriptomic Analysis Reveals the Crucial Roles of PANoptosis in Fungal Keratitis

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Xizhan Xu; Yuan Wei; Jinding Pang; Zhenyu Wei; Leying Wang; Qiankun Chen; Zhiqun Wang; Yang Zhang; Kexin Chen; Yan Peng; Zijun Zhang; Jiamin Liu; Yuheng Zhang; Zi-Bing Jin; Qingfeng Liang
TAGS: cornea, fungal keratitis, immune response, mice, mycoses, time factors, genes, infections, gene expression profiling
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):6. doi: https://doi.org/10.1167/iovs.64.3.6

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2023

The RNA m 5 C Methylase NSUN2 Modulates Corneal Epithelial Wound Healing

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Guangying Luo; Weiwei Xu; Xiaoyan Chen; Wenji Xu; Shuai Yang; Jiao Wang; Yong Lin; Peter S. Reinach; Dongsheng Yan
TAGS: rna, methyltransferase, cornea, wound healing, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):5. doi: https://doi.org/10.1167/iovs.64.3.5

Includes: Supplemental Content

Genetics February 2023

The Impaired Wound Healing Process Is a Major Factor in Remodeling of the Corneal Epithelium in Adult and Adolescent Patients With Keratoconus

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Katarzyna Jaskiewicz; Magdalena Maleszka-Kurpiel; Eliza Matuszewska; Michał Kabza; Malgorzata Rydzanicz; Robert Malinowski; Rafal Ploski; Jan Matysiak; Marzena Gajecka
TAGS: adolescent, adult, body regions, cornea, impaired wound healing, keratoconus, genes, epithelium, corneal epithelium, rna-seq
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):22. doi: https://doi.org/10.1167/iovs.64.2.22

Includes: Supplemental Content

Immunology and Microbiology February 2023

Topical Decorin Reduces Corneal Inflammation and Imparts Neuroprotection in a Mouse Model of Benzalkonium Chloride-induced Corneal Neuropathy

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Mengliang Wu; Laura E. Downie; Lisa J. Hill; Holly R. Chinnery
TAGS: cornea, keratitis, mice, neuropathy, chlorides, neuroprotection
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):20. doi: https://doi.org/10.1167/iovs.64.2.20

Includes: Supplemental Content

Artificial Intelligence February 2023

Machine Learning Analysis of Postkeratoplasty Endothelial Cell Images for the Prediction of Future Graft Rejection

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Naomi Joseph; Beth Ann Benetz; Prathyush Chirra; Harry Menegay; Silke Oellerich; Lamis Baydoun; Gerrit R. J. Melles; Jonathan H. Lass; David L. Wilson
TAGS: diagnostic imaging, endothelial cells, machine learning, rejection (psychology), transplant rejection, eye, descemet membrane endothelial keratoplasty, datasets
Trans. Vis. Sci. Tech.. 2023; 12(2):22. doi: https://doi.org/10.1167/tvst.12.2.22

Includes: Supplemental Content

Cornea & External Disease February 2023

Norepinephrine as an Enhancer Promoting Corneal Penetration of Riboflavin for Transepithelial Corneal Crosslinking

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Guoying Liu; Tan Li; Benxiang Qi; Ganyu Gong; Tengyou Guo; Qingjun Zhou; Vishal Jhanji; Bi Ning Zhang; Xianli Du
TAGS: cornea, corneal collagen cross-linking, norepinephrine, riboflavin, enhancer of transcription
Trans. Vis. Sci. Tech.. 2023; 12(2):21. doi: https://doi.org/10.1167/tvst.12.2.21

Includes: Supplemental Content

Cornea & External Disease February 2023

The Antibacterial Efficacy of High-Fluence PACK Cross-Linking Can Be Accelerated

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Nan-Ji Lu; Hendrik Koliwer-Brandl; Francesca Gilardoni; Nikki Hafezi; Boris Knyazer; Asaf Achiron; Reinhard Zbinden; Adrian Egli; Farhad Hafezi
TAGS: anti-bacterial agents, corneal collagen cross-linking, cross-linking
Trans. Vis. Sci. Tech.. 2023; 12(2):12. doi: https://doi.org/10.1167/tvst.12.2.12

Cornea & External Disease February 2023

Effect of Magnetic Microparticles on Cultivated Human Corneal Endothelial Cells

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Joo-Hee Park; Kangmin Lee; Choul Yong Park
TAGS: cell-derived microparticles, cornea, endothelial cells, toxic effect, cell survival, nanoparticles, neodymium, magnets
Trans. Vis. Sci. Tech.. 2023; 12(2):14. doi: https://doi.org/10.1167/tvst.12.2.14

Includes: Supplemental Content

Immunology and Microbiology February 2023

The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis

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Abdulraouf Ramadan; Zhiyi Cao; Mihaela Gadjeva; Tanweer S. Zaidi; Vijay A. Rathinam; Noorjahan Panjwani
TAGS: inflammasomes, keratitis, nlr family, pyrin domain-containing 3 protein, cornea, pseudomonas, mice, infections
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):11. doi: https://doi.org/10.1167/iovs.64.2.11

Includes: Supplemental Content

Glaucoma February 2023

The Effects of Negative Periocular Pressure on Biomechanics of the Optic Nerve Head and Cornea: A Computational Modeling Study

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Babak N. Safa; Adam Bleeker; John P. Berdahl; C. Ross Ethier
TAGS: biomechanics, body tissue, cornea, intraocular pressure, optic disk, computer simulation, eye
Trans. Vis. Sci. Tech.. 2023; 12(2):5. doi: https://doi.org/10.1167/tvst.12.2.5

Includes: Supplemental Content

Biochemistry and Molecular Biology January 2023

Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation

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Emma N. Finburgh; Olivier Mauduit; Takako Noguchi; Jennifer J. Bu; Anser A. Abbas; Dominic F. Hakim; Saverio Bellusci; Robyn Meech; Helen P. Makarenkova; Natalie A. Afshari
TAGS: fgf10 protein, human, cornea, mice, adult, langer-giedion syndrome, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):21. doi: https://doi.org/10.1167/iovs.64.1.21

Cornea January 2023

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

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Lili Ran; Jing Feng; Xia Qi; Ting Liu; Benxiang Qi; Kai Jiang; Zhenzhen Zhang; Yang Yu; Qingjun Zhou; Lixin Xie
TAGS: cornea, epithelium, mice, wound healing
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):19. doi: https://doi.org/10.1167/iovs.64.1.19

Includes: Supplemental Content

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Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mouse Corneal Epithelial Cells

Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study

Agreement of Total Keratometry and Posterior Keratometry Among IOLMaster 700, CASIA2, and Pentacam

Corneal Biomechanics After SMILE, Femtosecond-Assisted LASIK, and Photorefractive Keratectomy: A Matched Comparison Study

Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

Topical Ocular TRPV1 Antagonist SAF312 (Libvatrep) for Postoperative Pain After Photorefractive Keratectomy

Overactivation of Norepinephrine–β2-Adrenergic Receptor Axis Promotes Corneal Neovascularization

Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty

Time-Course Transcriptomic Analysis Reveals the Crucial Roles of PANoptosis in Fungal Keratitis

The RNA m 5 C Methylase NSUN2 Modulates Corneal Epithelial Wound Healing

The Impaired Wound Healing Process Is a Major Factor in Remodeling of the Corneal Epithelium in Adult and Adolescent Patients With Keratoconus

Topical Decorin Reduces Corneal Inflammation and Imparts Neuroprotection in a Mouse Model of Benzalkonium Chloride-induced Corneal Neuropathy

Machine Learning Analysis of Postkeratoplasty Endothelial Cell Images for the Prediction of Future Graft Rejection

Norepinephrine as an Enhancer Promoting Corneal Penetration of Riboflavin for Transepithelial Corneal Crosslinking

The Antibacterial Efficacy of High-Fluence PACK Cross-Linking Can Be Accelerated

Effect of Magnetic Microparticles on Cultivated Human Corneal Endothelial Cells

The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis

The Effects of Negative Periocular Pressure on Biomechanics of the Optic Nerve Head and Cornea: A Computational Modeling Study

Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation

Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice

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