Cornea

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Clinical and Epidemiologic Research June 2023

Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

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Arthur G. Fernandes; Palaiologos Alexopoulos; Armando Burgos-Rodriguez; Melween I. Martinez; Mark Ghassibi; Ilya Leskov; Lauren J. N. Brent; Noah Snyder-Mackler; John Danias; Gadi Wollstein; James P. Higham; Amanda D. Melin
TAGS: macaca mulatta, cataract, retinal drusen, eye, body weight
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):3. doi: https://doi.org/10.1167/iovs.64.7.3

Cornea May 2023

Z nf469 Plays a Critical Role in Regulating Synthesis of ECM: A Zebrafish Model of Brittle Cornea Syndrome

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Jing Bao; Xiaoning Yu; Xiyuan Ping; Xingchao Shentu; Jian Zou
TAGS: cornea, ehlers-danlos syndrome 6b, mutation, zebrafish, regulation, larva
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):29. doi: https://doi.org/10.1167/iovs.64.5.29

Includes: Supplemental Content

Cornea May 2023

Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats

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Kasumi Kikuchi; Yoshiaki Tagawa; Miyuki Murata; Susumu Ishida
TAGS: cornea, dry eye syndromes, hyperalgesia, ocular pain, rats, eye, excision
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):27. doi: https://doi.org/10.1167/iovs.64.5.27

Cornea May 2023

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

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Bi Ning Zhang; Benxiang Qi; Wai Kit Chu; Fangying Song; Suxia Li; Qiaoqiao Dong; Zheng Shao; Bin Zhang; Xianli Du; Xiubin Ma; Vishal Jhanji; Qingjun Zhou
TAGS: adrb2 gene, beta-2 adrenergic receptors, contact lenses, cornea, infections, keratitis, mice, norepinephrine, pseudomonas aeruginosa, epithelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):26. doi: https://doi.org/10.1167/iovs.64.5.26

Includes: Supplemental Content

Glaucoma May 2023

Influence of a Prostaglandin F2α Analogue on Corneal Hysteresis and Expression of Extracellular Matrix Metalloproteinases 3 and 9

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Constance Weber; Alexandra Buerger; Siegfried Priglinger; Karl Mercieca; Raffael Liegl
TAGS: cornea, corneal hysteresis, extracellular matrix, intraocular pressure, metalloproteases, prostaglandins, prostaglandins, synthetic, stromelysin 1, gelatinase b, donors
Trans. Vis. Sci. Tech.. 2023; 12(5):28. doi: https://doi.org/10.1167/tvst.12.5.28

Letters to the Editor May 2023

Why the Corvis Biomechanical Factor Should Only Be Used for Corneal Ectasia

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Robert Herber; Riccardo Vinciguerra; Elias Flockerzi; Paolo Vinciguerra; Berthold Seitz
TAGS: corneal ectasia
Trans. Vis. Sci. Tech.. 2023; 12(5):24. doi: https://doi.org/10.1167/tvst.12.5.24

Cornea & External Disease May 2023

Biomechanics of a Plant-Derived Sealant for Corneal Injuries

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Betty S. Liu; Matthew Liao; Willi L. Wagner; Hassan A. Khalil; Zi Chen; Maximilian Ackermann; Steven J. Mentzer
TAGS: adhesions, cornea, corneal injuries, plants, biomechanics
Trans. Vis. Sci. Tech.. 2023; 12(5):20. doi: https://doi.org/10.1167/tvst.12.5.20

Cornea May 2023

The TCF4 Trinucleotide Repeat Expansion of Fuchs’ Endothelial Corneal Dystrophy: Implications for the Anterior Segment of the Eye

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Jiaxin Hu; Xin Gong; Samantha T. Johnson; David R. Corey; V. Vinod Mootha
TAGS: body tissue, cornea, corneal endothelium, corneal stroma, endothelium, eye, hereditary corneal dystrophy, rna, trabecular meshwork, trinucleotide repeat expansion
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):16. doi: https://doi.org/10.1167/iovs.64.5.16

Includes: Supplemental Content

Cornea May 2023

The Presence of Guttae in Fuchs Endothelial Corneal Dystrophy Explants Correlates With Cellular Markers of Disease Progression

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Sébastien Méthot; Stéphanie Proulx; Isabelle Brunette; Patrick J. Rochette
TAGS: disease progression, endothelium, hereditary corneal dystrophy, mitochondria, chronic exertional compartment syndrome, calcium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):13. doi: https://doi.org/10.1167/iovs.64.5.13

Includes: Supplemental Content

Cornea & External Disease May 2023

How Modifications of Corneal Cross-Linking Protocols Influence Corneal Resistance to Enzymatic Digestion and Treatment Depth

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Malwina Kowalska; Elisa Mischi; Szymon Stoma; Simon F. Nørrelykke; Sonja Hartnack; Simon A. Pot
TAGS: cornea, corneal collagen cross-linking, digestion, riboflavin
Trans. Vis. Sci. Tech.. 2023; 12(5):18. doi: https://doi.org/10.1167/tvst.12.5.18

Includes: Supplemental Content

Cornea & External Disease May 2023

Corticosteroid–Antibiotic Interactions in Bacteria that Cause Corneal Infection

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Hun Lee; So Myoung Kim; Md. Intazur Rahaman; Dong Ju Kang; Changhyun Kim; Tae-im Kim; So Won Kim
TAGS: adrenal corticosteroids, antibiotics, bacteria, corneal infections, glucocorticoids, mineralocorticoids, cornea, anti-bacterial agents
Trans. Vis. Sci. Tech.. 2023; 12(5):16. doi: https://doi.org/10.1167/tvst.12.5.16

Includes: Supplemental Content

Cornea & External Disease May 2023

Cell Biology of Spontaneous Persistent Epithelial Defects After Photorefractive Keratectomy in Rabbits

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Lycia Pedral Sampaio; Valeria Villabona Martinez; Thomas Michael Shiju; Guilherme S. L. Hilgert; Marcony R. Santhiago; Steven E. Wilson
TAGS: cellular biology, cornea, epithelium, keratectomy, oryctolagus cuniculus, persistence, surgical procedures, operative, myofibroblasts, collagen type iv, vimentin
Trans. Vis. Sci. Tech.. 2023; 12(5):15. doi: https://doi.org/10.1167/tvst.12.5.15

Includes: Supplemental Content

Artificial Intelligence May 2023

Deep Learning Using Preoperative AS-OCT Predicts Graft Detachment in DMEK

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Alastair Patefield; Yanda Meng; Matteo Airaldi; Giulia Coco; Sabrina Vaccaro; Mohit Parekh; Francesco Semeraro; Kunal A. Gadhvi; Stephen B. Kaye; Yalin Zheng; Vito Romano
TAGS: deep learning, descemet membrane endothelial keratoplasty, preoperative care, tissue transplants
Trans. Vis. Sci. Tech.. 2023; 12(5):14. doi: https://doi.org/10.1167/tvst.12.5.14

Cornea & External Disease May 2023

Effect of Corneal Collagen Cross-Linking on Subsequent Corneal Fungal Infection in Rats

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Fangli Peng; Qi Xie; Jiaqi Chen; Yiting Fang; Wei Xu; Dan Jiang; Wei Chen
TAGS: cornea, corneal collagen cross-linking, fungal keratitis, mycoses, rats, symptom aggravating factors, keratitis
Trans. Vis. Sci. Tech.. 2023; 12(5):12. doi: https://doi.org/10.1167/tvst.12.5.12

Immunology and Microbiology May 2023

Staphylococcal Enterotoxins Promote Virulence in Bacterial Keratitis

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William L. Johnson; Michael Sohn; Collynn F. Woeller; Rachel A. F. Wozniak
TAGS: enterotoxins, keratitis, virulence, staphylococcal enterotoxins, bacterial keratitis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):5. doi: https://doi.org/10.1167/iovs.64.5.5

Includes: Supplemental Content

Cornea & External Disease April 2023

Porcine Cornea Storage Ex Vivo Model as an Alternative to Human Donor Tissues for Investigations of Endothelial Layer Preservation

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Umberto Rodella; Lorenzo Bosio; Stefano Ferrari; Claudio Gatto; Laura Giurgola; Orietta Rossi; Stefano Ciciliot; Eugenio Ragazzi; Diego Ponzin; Jana D'Amato Tóthová
TAGS: body tissue, cornea, endothelium, suidae, donors
Trans. Vis. Sci. Tech.. 2023; 12(4):24. doi: https://doi.org/10.1167/tvst.12.4.24

Includes: Supplemental Content

Cornea April 2023

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

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Brian C. Leonard; Sangwan Park; Soohyun Kim; Laura J. Young; Iman Jalilian; Krista Cosert; Xunzhi Zhang; Jessica M. Skeie; Hanna Shevalye; Nayeli Echeverria; Vanessa Rozo; Xin Gong; Chao Xing; Christopher J. Murphy; Mark A. Greiner; V. Vinod Mootha; Vijay Krishna Raghunathan; Sara M. Thomasy
TAGS: cornea, endothelium, hereditary corneal dystrophy, mice, signs and symptoms, proteins
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):22. doi: https://doi.org/10.1167/iovs.64.4.22

Includes: Supplemental Content

Cornea & External Disease April 2023

Characterization of the Molecular Weight of Hyaluronan in Eye Products Using a Novel Method of Size Exclusion High-Pressure Liquid Chromatography

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Lawrence Nguyen; Xiao Lin; Sudhir Verma; Sudan Puri; Vincent Hascall; Tarsis Ferreira Gesteira; Vivien J. Coulson-Thomas
TAGS: drugs, non-prescription, eye, eyedrops, high pressure liquid chromatography procedure, molecular mass, hyaluronan, familial amyloid nephropathy with urticaria and deafness, corneal epithelial cells
Trans. Vis. Sci. Tech.. 2023; 12(4):13. doi: https://doi.org/10.1167/tvst.12.4.13

Includes: Supplemental Content

Cornea April 2023

Schwann Cells Are Key Regulators of Corneal Epithelial Renewal

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Kaveh Mirmoeini; Kiana Tajdaran; Jennifer Zhang; Tessa Gordon; Asim Ali; David R. Kaplan; Konstantin Feinberg; Gregory H. Borschel
TAGS: cornea, epithelium, spinal cord stimulation, wound healing, schwann cells, ablation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):7. doi: https://doi.org/10.1167/iovs.64.4.7

Includes: Supplemental Content

Cornea & External Disease April 2023

Identification of the Vibrational Optical Coherence Tomography Corneal Cellular Peak

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Nathalie D. Daher; Ahmed Saeed Saad; Hiram J. Jimenez; Tatyana Milman; Orlando G. Gonzalez-Martinez; Tanmay Deshmukh; Jose S. Pulido; Frederick H. Silver; Dominick A. Benedetto; Christopher J. Rapuano; Zeba A. Syed
TAGS: cornea, optical coherence tomography, eye
Trans. Vis. Sci. Tech.. 2023; 12(4):11. doi: https://doi.org/10.1167/tvst.12.4.11

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Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

Z nf469 Plays a Critical Role in Regulating Synthesis of ECM: A Zebrafish Model of Brittle Cornea Syndrome

Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis

Influence of a Prostaglandin F2α Analogue on Corneal Hysteresis and Expression of Extracellular Matrix Metalloproteinases 3 and 9

Why the Corvis Biomechanical Factor Should Only Be Used for Corneal Ectasia

Biomechanics of a Plant-Derived Sealant for Corneal Injuries

The TCF4 Trinucleotide Repeat Expansion of Fuchs’ Endothelial Corneal Dystrophy: Implications for the Anterior Segment of the Eye

The Presence of Guttae in Fuchs Endothelial Corneal Dystrophy Explants Correlates With Cellular Markers of Disease Progression

How Modifications of Corneal Cross-Linking Protocols Influence Corneal Resistance to Enzymatic Digestion and Treatment Depth

Corticosteroid–Antibiotic Interactions in Bacteria that Cause Corneal Infection

Cell Biology of Spontaneous Persistent Epithelial Defects After Photorefractive Keratectomy in Rabbits

Deep Learning Using Preoperative AS-OCT Predicts Graft Detachment in DMEK

Effect of Corneal Collagen Cross-Linking on Subsequent Corneal Fungal Infection in Rats

Staphylococcal Enterotoxins Promote Virulence in Bacterial Keratitis

Porcine Cornea Storage Ex Vivo Model as an Alternative to Human Donor Tissues for Investigations of Endothelial Layer Preservation

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

Characterization of the Molecular Weight of Hyaluronan in Eye Products Using a Novel Method of Size Exclusion High-Pressure Liquid Chromatography

Schwann Cells Are Key Regulators of Corneal Epithelial Renewal

Identification of the Vibrational Optical Coherence Tomography Corneal Cellular Peak

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