Eye Anatomy and Disorders

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Physiology and Pharmacology June 2021

Differential and Altered Spatial Distribution of Complement Expression in Age-Related Macular Degeneration

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John T. Demirs; Junzheng Yang; Maura A. Crowley; Michael Twarog; Omar Delgado; Yubin Qiu; Stephen Poor; Dennis S. Rice; Thaddeus P. Dryja; Karen Anderson; Sha-Mei Liao
TAGS: complement system proteins, eye, rna, messenger, age-related macular degeneration, choroid, neural retina, donors
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):26. doi: https://doi.org/10.1167/iovs.62.7.26

Includes: Supplemental Content

Cornea June 2021

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol

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Zhixin Jiang; Huan Zhang; Juan Gao; Hao Yu; Ruifang Han; Lin Zhu; Xi Chen; Qian Fan; Peng Hao; Liming Wang; Xuan Li
TAGS: attenuation, cornea, corneal epithelial cells, resveratrol, sars-cov-2, corneal epithelium, tmprss2 gene, cytokine, fluorescent antibody technique, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):25. doi: https://doi.org/10.1167/iovs.62.7.25

Article June 2021

Transsaccadic visual perception of foveal compared to peripheral environmental changes

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Sonia Bansal; Wilsaan M. Joiner
TAGS: eye movement, saccades, visual perception, fovea centralis, perception, reaction time
Journal of Vision. 2021; 21(6):12. doi: https://doi.org/10.1167/jov.21.6.12

Includes: Supplemental Content

Articles June 2021

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression

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Osamah Saeedi; Michael V. Boland; Loris D'Acunto; Ramya Swamy; Vikram Hegde; Surabhi Gupta; Amin Venjara; Joby Tsai; Jonathan S. Myers; Sarah R. Wellik; Gustavo DeMoraes; Louis R. Pasquale; Lucy Q. Shen; Yangjiani Li; Tobias Elze
TAGS: glaucoma, machine learning, visual fields, eye, datasets
Trans. Vis. Sci. Tech.. 2021; 10(7):27. doi: https://doi.org/10.1167/tvst.10.7.27

Includes: Supplemental Content

Articles June 2021

Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics

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Eric M. Moult; Yunchan Hwang; Yingying Shi; Liang Wang; Siyu Chen; Nadia K. Waheed; Giovanni Gregori; Philip J. Rosenfeld; James G. Fujimoto
TAGS: atrophy, eye, growth rate, kinetics
Trans. Vis. Sci. Tech.. 2021; 10(7):26. doi: https://doi.org/10.1167/tvst.10.7.26

Includes: Supplemental Content

Glaucoma June 2021

Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma

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Wouter H. G. Hubens; Julian Krauskopf; Henny J. M. Beckers; Jos C. S. Kleinjans; Carroll A. B. Webers; Theo G. M. F. Gorgels
TAGS: glaucoma, hypertension, micrornas, open-angle glaucoma, plasma, rna, small, aqueous humor, rna-seq, biological markers
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):24. doi: https://doi.org/10.1167/iovs.62.7.24

Includes: Supplemental Content

Lens June 2021

Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice

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Renita Maria Martis; Bo Li; Paul James Donaldson; Julie Ching-Hsia Lim
TAGS: cataract, cystine, lens (device), lens, crystalline, mice, glutamate, mice, knockout, antiporter, cataract, senile, cysteine
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):23. doi: https://doi.org/10.1167/iovs.62.7.23

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2021

Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations

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Xiaofen Jin; Juanjuan Zhang; Qiuzi Yi; Feilong Meng; Jialing Yu; Yanchun Ji; Jun Q. Mo; Yi Tong; Pingping Jiang; Min-Xin Guan
TAGS: mitochondria, mutation, optic atrophy, hereditary, leber, cell lines, proteins, western blotting
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):22. doi: https://doi.org/10.1167/iovs.62.7.22

Includes: Supplemental Content

Article June 2021

Age effects on saccadic suppression of luminance and color

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Doris I. Braun; Alexander C. Schütz; Karl R. Gegenfurtner
TAGS: color, luminance, saccades, photopsia, contrast sensitivity
Journal of Vision. 2021; 21(6):11. doi: https://doi.org/10.1167/jov.21.6.11

Articles June 2021

Modeling Cone/Cone–Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina

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Yuwei Wang; Xiaomeng Li; Yang Yu; Jian Liang; Yang Liu; Yuhong Chen; Xinyue Bai; Jieqiong Chen; Fenghua Wang; Xueting Luo; Xiaodong Sun
TAGS: carrying, mice, mutation, pathology, photoreceptors, protein overexpression, proteins, retina, retinal cone, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2021; 10(7):25. doi: https://doi.org/10.1167/tvst.10.7.25

Immunology and Microbiology June 2021

Retinal Pigment Epithelial Cells Express Antimicrobial Peptide Lysozyme – A Novel Mechanism of Innate Immune Defense of the Blood-Retina Barrier

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Jian Liu; Caijiao Yi; Wei Ming; Miao Tang; Xiao Tang; Chang Luo; Bo Lei; Mei Chen; Heping Xu
TAGS: muramidase, retinal pigment cell, antimicrobials, peptides
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):21. doi: https://doi.org/10.1167/iovs.62.7.21

Visual Neuroscience June 2021

Synaptosomal Actin Dynamics in the Developmental Visual Cortex Regulate Behavioral Visual Acuity in Rats

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Ai-Ling Bi; Yue-Ying Zhang; Zhi-Yuan Lu; Hong-Ying Tang; Xiu-Yan Zhang; Zi-Han Zhang; Bo-Qin Li; Da-Dong Guo; Sheng Gong; Qian Li; Xing-Rong Wang; Xiu-Zhen Lu; Hong-Sheng Bi
TAGS: actins, rats, visual acuity, visual cortex, mitochondria, primary visual cortex
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):20. doi: https://doi.org/10.1167/iovs.62.7.20

Includes: Supplemental Content

Articles June 2021

Microscope-Integrated OCT-Guided Volumetric Measurements of Subretinal Blebs Created by a Suprachoroidal Approach

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Ananth Sastry; Jianwei D. Li; William Raynor; Christian Viehland; Zhenxi Song; Liangyu Xu; Sina Farsiu; Joseph A. Izatt; Cynthia A. Toth; Lejla Vajzovic
TAGS: blister, volume, microscopes, volumetry, injections
Trans. Vis. Sci. Tech.. 2021; 10(7):24. doi: https://doi.org/10.1167/tvst.10.7.24

Articles June 2021

Macular Ischemia Quantification Using Deep-Learning Denoised Optical Coherence Tomography Angiography in Branch Retinal Vein Occlusion

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Ling Yeung; Yih-Cherng Lee; Yu-Tze Lin; Tay-Wey Lee; Chi-Chun Lai
TAGS: angiogram, deep learning, ischemia, optical coherence tomography, venous retinal branch occlusion, eye
Trans. Vis. Sci. Tech.. 2021; 10(7):23. doi: https://doi.org/10.1167/tvst.10.7.23

Includes: Supplemental Content

Articles June 2021

Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy

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Laura Alves de Figueiredo; João Victor Pacheco Dias; Mariza Polati; Pedro Carlos Carricondo; Iara Debert
TAGS: artificial intelligence, eye, strabismus, gaze
Trans. Vis. Sci. Tech.. 2021; 10(7):22. doi: https://doi.org/10.1167/tvst.10.7.22

Includes: Multimedia, Supplemental Content

Retina June 2021

Association Between Gut Microbial Abundance and Sight-Threatening Diabetic Retinopathy

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Rehana Khan; Abhishek Sharma; Raghul Ravikumar; Avani Parekh; Ramyaa Srinivasan; Ronnie Jacob George; Rajiv Raman
TAGS: diabetic retinopathy, dysbiosis, vision, diabetes mellitus, diabetes mellitus, type 2, massively-parallel genome sequencing, intestinal bacteria
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):19. doi: https://doi.org/10.1167/iovs.62.7.19

Cornea June 2021

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function

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Zhenying Shang; Chenxi Li; Xuemei Liu; Manhong Xu; Xiaomin Zhang; Xiaorong Li; Colin J. Barnstable; Shaozhen Zhao; Joyce Tombran-Tink
TAGS: cornea, mice, gene deletion, nerve supply
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):18. doi: https://doi.org/10.1167/iovs.62.7.18

Articles June 2021

Pix2pix Conditional Generative Adversarial Networks for Scheimpflug Camera Color-Coded Corneal Tomography Image Generation

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Hazem Abdelmotaal; Ahmed A. Abdou; Ahmed F. Omar; Dalia Mohamed El-Sebaity; Khaled Abdelazeem
TAGS: color, cornea, datasets, generators, tomography, training, keratoconus
Trans. Vis. Sci. Tech.. 2021; 10(7):21. doi: https://doi.org/10.1167/tvst.10.7.21

Articles June 2021

Five-Category Intelligent Auxiliary Diagnosis Model of Common Fundus Diseases Based on Fundus Images

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Bo Zheng; Qin Jiang; Bing Lu; Kai He; Mao-Nian Wu; Xiu-Lan Hao; Hong-Xia Zhou; Shao-Jun Zhu; Wei-Hua Yang
TAGS: fundi normal, glaucoma, learning, myopia, ophthalmologists, training, transfer technique, sensitivity and specificity, diabetic retinopathy, physicians
Trans. Vis. Sci. Tech.. 2021; 10(7):20. doi: https://doi.org/10.1167/tvst.10.7.20

Article June 2021

N -methyl d -aspartate receptor hypofunction reduces visual contextual integration

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Alexander Schielke; Bart Krekelberg
TAGS: aspartate, illusions, ketamine, eye movement, injections
Journal of Vision. 2021; 21(6):9. doi: https://doi.org/10.1167/jov.21.6.9

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Differential and Altered Spatial Distribution of Complement Expression in Age-Related Macular Degeneration

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol

Transsaccadic visual perception of foveal compared to peripheral environmental changes

Development and Comparison of Machine Learning Algorithms to Determine Visual Field Progression

Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics

Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma

Early Onset of Age-Related Cataracts in Cystine/Glutamate Antiporter Knockout Mice

Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations

Age effects on saccadic suppression of luminance and color

Modeling Cone/Cone–Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina

Retinal Pigment Epithelial Cells Express Antimicrobial Peptide Lysozyme – A Novel Mechanism of Innate Immune Defense of the Blood-Retina Barrier

Synaptosomal Actin Dynamics in the Developmental Visual Cortex Regulate Behavioral Visual Acuity in Rats

Microscope-Integrated OCT-Guided Volumetric Measurements of Subretinal Blebs Created by a Suprachoroidal Approach

Macular Ischemia Quantification Using Deep-Learning Denoised Optical Coherence Tomography Angiography in Branch Retinal Vein Occlusion

Strabismus and Artificial Intelligence App: Optimizing Diagnostic and Accuracy

Association Between Gut Microbial Abundance and Sight-Threatening Diabetic Retinopathy

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function

Pix2pix Conditional Generative Adversarial Networks for Scheimpflug Camera Color-Coded Corneal Tomography Image Generation

Five-Category Intelligent Auxiliary Diagnosis Model of Common Fundus Diseases Based on Fundus Images

N -methyl d -aspartate receptor hypofunction reduces visual contextual integration

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