Eye Anatomy and Disorders

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Articles May 2022

Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry

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Thomas M. W. Buckley; Amandeep Singh Josan; Laura J. Taylor; Jasleen K. Jolly; Jasmina Cehajic-Kapetanovic; Robert E. MacLaren
TAGS: octopus, perimetry, retinitis pigmentosa, visual fields
Trans. Vis. Sci. Tech.. 2022; 11(5):15. doi: https://doi.org/10.1167/tvst.11.5.15

Articles May 2022

Modeling the Effects of Disease, Drug Properties, and Material on Drug Transport From Intraocular Lenses

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Danielle P. Clasky; Louise Meunier; Laura A. Wells
TAGS: choroid, drug clearance, drug release, drug transport, eye, fluid flow, intraocular lens implant device, mass or substance concentration per volume, steady state, vascular flow
Trans. Vis. Sci. Tech.. 2022; 11(5):14. doi: https://doi.org/10.1167/tvst.11.5.14

Includes: Supplemental Content

Articles May 2022

Ultrasound Targeted Microbubble Destruction Promotes the Therapeutic Effect of HUMSC Transplantation on Glaucoma-Caused Optic Nerve Injury in Rabbits

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Tianhui Zhu; Xiaosheng Huang; Shiming Peng; Ye Ye; Jun Zhao
TAGS: glaucoma, microbubbles, optic nerve injuries, oryctolagus cuniculus, transplantation, ultrasonography
Trans. Vis. Sci. Tech.. 2022; 11(5):12. doi: https://doi.org/10.1167/tvst.11.5.12

Articles May 2022

Prediction of Retinal Ganglion Cell Counts Considering Various Displacement Methods From OCT-Derived Ganglion Cell–Inner Plexiform Layer Thickness

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Janelle Tong; Jack Phu; David Alonso-Caneiro; Sieu K. Khuu; Michael Kalloniatis
TAGS: cohort studies, ganglia, meridians, retinal cone, retinal ganglion cells
Trans. Vis. Sci. Tech.. 2022; 11(5):13. doi: https://doi.org/10.1167/tvst.11.5.13

Includes: Supplemental Content

Lens May 2022

Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

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Kehao Wang; Masato Hoshino; Kentaro Uesugi; Naoto Yagi; Barbara K. Pierscionek; Usha P. Andley
TAGS: crystallins, lens (device), lens, crystalline, mice, optics, oxysterols, refractive index, alpha-crystallin b chain, cataract
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):15. doi: https://doi.org/10.1167/iovs.63.5.15

Includes: Supplemental Content

Retina May 2022

Ablation of Ctrp9 , Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina

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Daiki Inooka; Yoshihiro Omori; Noriyuki Ouchi; Koji Ohashi; Yuto Kawakami; Yoshito Koyanagi; Chieko Koike; Hiroko Terasaki; Koji M. Nishiguchi; Shinji Ueno
TAGS: ligands, mice, retina, retinal cone, ablation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):14. doi: https://doi.org/10.1167/iovs.63.5.14

Includes: Supplemental Content

Retina May 2022

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse

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Wanjing Huang; Qiang Xu; Feng Liu; Jing Su; Dongchang Xiao; Lei Tang; Zhao-Zhe Hao; Ruifeng Liu; Kangjian Xiang; Yalan Bi; Zhichao Miao; Xialin Liu; Yizhi Liu; Sheng Liu
TAGS: abdominal compartment syndrome, acute coronary syndromes, american cancer society, american college of surgeons, mice, retina, immunohistochemistry, amacrine cells
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):13. doi: https://doi.org/10.1167/iovs.63.5.13

Includes: Supplemental Content

Cornea May 2022

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

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Maite López-López; Uxía Regueiro; Susana Belén Bravo; María del Pilar Chantada-Vázquez; Carmen Pena; Elío Díez-Feijoo; Pablo Hervella; Isabel Lema
TAGS: keratoconus, proteins, proteome, proteomics, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):12. doi: https://doi.org/10.1167/iovs.63.5.12

Includes: Supplemental Content

Articles May 2022

Deep Learning for Glaucoma Detection and Identification of Novel Diagnostic Areas in Diverse Real-World Datasets

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Erfan Noury; Suria S. Mannil; Robert T. Chang; An Ran Ran; Carol Y. Cheung; Suman S. Thapa; Harsha L. Rao; Srilakshmi Dasari; Mohammed Riyazuddin; Dolly Chang; Sriharsha Nagaraj; Clement C. Tham; Reza Zadeh
TAGS: datasets, glaucoma, deep learning
Trans. Vis. Sci. Tech.. 2022; 11(5):11. doi: https://doi.org/10.1167/tvst.11.5.11

Includes: Supplemental Content

Articles May 2022

The NEI VFQ-25C: Calibrating Items in the National Eye Institute Visual Function Questionnaire-25 to Enable Comparison of Outcome Measures

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Judith E. Goldstein; Chris Bradley; Alden L. Gross; Marylou Jackson; Neil Bressler; Robert W. Massof
TAGS: eye, outcome measures, questionnaires, vision, datasets, rasch model
Trans. Vis. Sci. Tech.. 2022; 11(5):10. doi: https://doi.org/10.1167/tvst.11.5.10

Articles May 2022

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

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Ke Shi; Xinxin Li; Jingfa Zhang; Xiaodong Sun
TAGS: genes, intraocular melanoma, metabolism, patient prognosis
Trans. Vis. Sci. Tech.. 2022; 11(5):9. doi: https://doi.org/10.1167/tvst.11.5.9

Includes: Supplemental Content

Articles May 2022

Evaluation of Spatially Targeted Scleral Stiffening on Neuroprotection in a Rat Model of Glaucoma

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Brandon G. Gerberich; Bailey G. Hannon; Dillon M. Brown; A. Thomas Read; Matthew D. Ritch; Elisa Schrader Echeverri; Lauren Nichols; Cahil Potnis; Sreesh Sridhar; Maya G. Toothman; Stephen A. Schwaner; Erin J. Winger; Hannah Huang; Gabby S. Gershon; Andrew J. Feola; Machelle T. Pardue; Mark R. Prausnitz; C. Ross Ethier
TAGS: eye, glaucoma, sclera, microspheres, intraocular pressure, neuroprotection, hypertension, electroretinography, axon
Trans. Vis. Sci. Tech.. 2022; 11(5):7. doi: https://doi.org/10.1167/tvst.11.5.7

Includes: Supplemental Content

Letters to the Editor May 2022

Author Response: Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

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Omer Trivizki; Eric Michael Moult; Liang Wang; Prashanth Iyer; Yingying Shi; Giovanni Gregori; William Feuer; James G. Fujimoto; Philip J. Rosenfeld
TAGS: atrophy, growth rate, macular neovascularization
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):11. doi: https://doi.org/10.1167/iovs.63.5.11

Letters to the Editor May 2022

Re: Trivizki et al. Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

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Maximilian Pfau; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: atrophy, growth rate, macular neovascularization
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):10. doi: https://doi.org/10.1167/iovs.63.5.10

Articles May 2022

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

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Wei Zhang; Alfrun Schönberg; Felix Bock; Claus Cursiefen
TAGS: cd40 ligand, cornea, eye, eyedrops, keratoplasty, rejection (psychology), telomeric repeat amplification protocol, thyroid hormone associated protein complex, allografting, transplantation
Trans. Vis. Sci. Tech.. 2022; 11(5):6. doi: https://doi.org/10.1167/tvst.11.5.6

Includes: Supplemental Content

Articles May 2022

The Usefulness of Assessing Glaucoma Progression With Postprocessed Visual Field Data

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Sampson L. Abu; Shervonne Poleon; Lyne Racette
TAGS: datasets, glaucoma, visual fields, eye
Trans. Vis. Sci. Tech.. 2022; 11(5):5. doi: https://doi.org/10.1167/tvst.11.5.5

Includes: Supplemental Content

Retina May 2022

Alpha-Smooth Muscle Actin Expression and Parafoveal Blood Flow Pathways Are Altered in Preclinical Diabetic Retinopathy

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Dong An; Jonathan Chung-Wah-Cheong; Dao-Yi Yu; Chandrakumar Balaratnasingam
TAGS: actins, blood capillaries, diabetic retinopathy, muscle, parafoveal region, vascular flow, donors, pericytes, perfusion, eye
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):8. doi: https://doi.org/10.1167/iovs.63.5.8

Includes: Supplemental Content

Articles May 2022

The Effect of Induced Intraocular Stray Light on Recognition Thresholds for Pseudo-High-Pass Filtered Letters

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Nilpa Shah; Steven C. Dakin; Pádraig J. Mulholland; Kalina Racheva; Juliane Matlach; Roger S. Anderson
TAGS: blindness, cataract, complement membrane attack complex, eye, filters, lens (device), lens, crystalline, mac protocol, mdc protocol, mid upper arm circumference
Trans. Vis. Sci. Tech.. 2022; 11(5):4. doi: https://doi.org/10.1167/tvst.11.5.4

Cornea May 2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

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Ren Liu; Jing Li; Yue Xu; Ziyan Chen; Huijing Ye; Jinhui Tang; Lai Wei; Lingyi Liang
TAGS: cytokine, epithelial cells, lipogenesis, meibomian gland, melatonin, mitogen-activated protein kinases, proteins, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):6. doi: https://doi.org/10.1167/iovs.63.5.6

Includes: Supplemental Content

Retina May 2022

Photoreceptor Manifestations of Primary Mitochondrial Optic Nerve Disorders

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Yin-Hsi Chang; Eugene Yu-Chuan Kang; Pei-Kang Liu; Sarah R. Levi; Hung-Hsuan Wang; Yun-Ju Tseng; Go Hun Seo; Hane Lee; Lung-Kun Yeh; Kuan-Jen Chen; Wei-Chi Wu; Chi-Chun Lai; Laura Liu; Nan-Kai Wang
TAGS: mitochondria, optic atrophy, autosomal dominant, optic atrophy, hereditary, leber, optic nerve disorders, pathophysiology, photoreceptors, tissue degeneration, spectral domain-optical coherence tomography, mutation, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):5. doi: https://doi.org/10.1167/iovs.63.5.5

Includes: Supplemental Content

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Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry

Modeling the Effects of Disease, Drug Properties, and Material on Drug Transport From Intraocular Lenses

Ultrasound Targeted Microbubble Destruction Promotes the Therapeutic Effect of HUMSC Transplantation on Glaucoma-Caused Optic Nerve Injury in Rabbits

Prediction of Retinal Ganglion Cell Counts Considering Various Displacement Methods From OCT-Derived Ganglion Cell–Inner Plexiform Layer Thickness

Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

Ablation of Ctrp9 , Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

Deep Learning for Glaucoma Detection and Identification of Novel Diagnostic Areas in Diverse Real-World Datasets

The NEI VFQ-25C: Calibrating Items in the National Eye Institute Visual Function Questionnaire-25 to Enable Comparison of Outcome Measures

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

Evaluation of Spatially Targeted Scleral Stiffening on Neuroprotection in a Rat Model of Glaucoma

Author Response: Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

Re: Trivizki et al. Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

The Usefulness of Assessing Glaucoma Progression With Postprocessed Visual Field Data

Alpha-Smooth Muscle Actin Expression and Parafoveal Blood Flow Pathways Are Altered in Preclinical Diabetic Retinopathy

The Effect of Induced Intraocular Stray Light on Recognition Thresholds for Pseudo-High-Pass Filtered Letters

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

Photoreceptor Manifestations of Primary Mitochondrial Optic Nerve Disorders

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