Eye Anatomy and Disorders

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Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology September 2021

Novel Foveal Features Associated With Vision Impairment in Multiple Sclerosis

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Aubrey Hargrave; Nripun Sredar; Fareshta Khushzad; Jennifer Yarp; Anna Tomczak; May Han; Lucas Kipp; Alfredo Dubra; Heather E. Moss
TAGS: diagnostic imaging, eye, multiple sclerosis, visual impairment, retina, vision, retinal nerve fiber layer, ganglia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):27. doi: https://doi.org/10.1167/iovs.62.12.27

Multidisciplinary Ophthalmic Imaging September 2021

Impact of Structural Changes on Multifocal Electroretinography in Patients With Use of Hydroxychloroquine

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Enrico Borrelli; Marco Battista; Maria Lucia Cascavilla; Chiara Viganò; Federico Borghesan; Nicolò Nicolini; Lidia Clemente; Riccardo Sacconi; Costanza Barresi; Alessandro Marchese; Elisabetta Miserocchi; Giulio Modorati; Francesco Bandello; Giuseppe Querques
TAGS: electroretinography, hydroxychloroquine, retinal diseases, toxic effect, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):28. doi: https://doi.org/10.1167/iovs.62.12.28

Includes: Supplemental Content

Article September 2021

Familiar size affects the perceived size and distance of real objects even with binocular vision

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Margaret V. Maltz; Kevin M. Stubbs; Derek J. Quinlan; Anna M. Rzepka; Jocelyn R. Martin; Jody C. Culham
TAGS: cues, perception, death, vision, binocular
Journal of Vision. 2021; 21(10):21. doi: https://doi.org/10.1167/jov.21.10.21

Special Issue September 2021

A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Interim Clinical Trial Results

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Matthew A. Petoe; Samuel A. Titchener; Maria Kolic; William G. Kentler; Carla J. Abbott; David A. X. Nayagam; Elizabeth K. Baglin; Jessica Kvansakul; Nick Barnes; Janine G. Walker; Stephanie B. Epp; Kiera A. Young; Lauren N. Ayton; Chi D. Luu; Penelope J. Allen; for the Bionics Institute and Centre for Eye Research Australia Retinal Prosthesis Consortium
TAGS: prostheses, surgical procedures, operative, vision, visual prosthesis, eye, mobility, touch sensation, bionics, avoidance behavior
Trans. Vis. Sci. Tech.. 2021; 10(10):12. doi: https://doi.org/10.1167/tvst.10.10.12

Includes: Supplemental Content

Articles September 2021

A Deep Learning System for Automatic Assessment of Anterior Chamber Angle in Ultrasound Biomicroscopy Images

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Wensai Wang; Lingxiao Wang; Xiaochun Wang; Sheng Zhou; Song Lin; Jun Yang
TAGS: anterior chamber of eye, deep learning, sclera, ultrasound biomicroscopy
Trans. Vis. Sci. Tech.. 2021; 10(11):21. doi: https://doi.org/10.1167/tvst.10.11.21

Articles September 2021

Quantitative Analysis of Eyeball Rotation During Lateral Gaze in Intermittent Exotropia: A Magnetic Resonance Imaging Study

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Yeji Moon; Seung Hak Shin; Ji Young Lee; Won June Lee; Yu Jeong Kim; Jin-Ju Yang; Su-Jae Lee; Han Woong Lim
TAGS: exotropia, exotropia, intermittent, eye, gaze, magnetic resonance imaging, adduction
Trans. Vis. Sci. Tech.. 2021; 10(11):20. doi: https://doi.org/10.1167/tvst.10.11.20

Articles September 2021

Retinal Vascular Resistance Significantly Correlates With Visual Acuity After 1 Year of Anti-VEGF Therapy in Central Retinal Vein Occlusion

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Makiko Matsumoto; Kiyoshi Suzuma; Fumito Akiyama; Kanako Yamada; Shiori Harada; Eiko Tsuiki; Takashi Kitaoka
TAGS: anti-vascular endothelial growth factor therapy, central retinal vein occlusion, vascular resistance, visual acuity, injections
Trans. Vis. Sci. Tech.. 2021; 10(11):19. doi: https://doi.org/10.1167/tvst.10.11.19

Articles September 2021

Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography

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Shin Kadomoto; Yuki Muraoka; Akihito Uji; Sotaro Ooto; Kentaro Kawai; Masaharu Ishikura; Naomi Nishigori; Tadamichi Akagi; Akitaka Tsujikawa
TAGS: diagnostic imaging, optical coherence tomography, optics, retinal cone, retina, fovea centralis, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2021; 10(11):17. doi: https://doi.org/10.1167/tvst.10.11.17

Clinical Trials September 2021

Integrating Clinical Data and Tear Proteomics to Assess Efficacy, Ocular Surface Status, and Biomarker Response After Orthokeratology Lens Wear

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Jimmy S.H. Tse; Jimmy K.W. Cheung; Gigi T.K. Wong; Thomas C. Lam; Kai Yip Choi; Katherine H.Y. So; Christie D.M. Lam; Andes Y.H. Sze; Angel C.K. Wong; Gigi M.C. Yee; Henry H.L. Chan
TAGS: biological markers, lens (device), lens, crystalline, orthokeratology, proteins, proteome, proteomics, safety, cornea
Trans. Vis. Sci. Tech.. 2021; 10(11):18. doi: https://doi.org/10.1167/tvst.10.11.18

Includes: Supplemental Content

Retina September 2021

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

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Yinting Song; Mengyu Liao; Xiao Zhao; Han Han; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: macrophages, massively-parallel genome sequencing, mucopolysaccharidoses, retinal pigment cell, vitreous body, cell-derived microparticles, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):26. doi: https://doi.org/10.1167/iovs.62.12.26

Includes: Supplemental Content

Lens September 2021

Spatially Resolved Proteomic Analysis of the Lens Extracellular Diffusion Barrier

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Zhen Wang; Lee S. Cantrell; Kevin L. Schey
TAGS: diffusion, lens (device), lens, crystalline, proteins, proteomics
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):25. doi: https://doi.org/10.1167/iovs.62.12.25

Includes: Supplemental Content

Article September 2021

Modeling refractive correction strategies in keratoconus

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Jos J. Rozema; Gareth D. Hastings; Jason Marsack; Carina Koppen; Raymond A. Applegate
TAGS: eye, keratoconus, lens (device), lens, crystalline, image quality, sclera
Journal of Vision. 2021; 21(10):18. doi: https://doi.org/10.1167/jov.21.10.18

Includes: Supplemental Content

Perspective September 2021

Coming of Age for the Photoreceptor Synapse

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Ellen Townes-Anderson; Eva Halasz; Weiwei Wang; Marco Zarbin
TAGS: photoreceptors, retinal cone, retinal detachment, rod photoreceptors, synapses, wounds and injuries, retina, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):24. doi: https://doi.org/10.1167/iovs.62.12.24

Special Issue September 2021

Corneal Collagen Cross-Linking Pretreatment Mitigates Injury-Induced Inflammation, Hemangiogenesis and Lymphangiogenesis In Vivo

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Yirui Zhu; Peter S. Reinach; Chaoxiang Ge; Yun Li; Biao Wu; Qi Xie; Louis Tong; Wei Chen
TAGS: corneal collagen cross-linking, inflammation, lymphangiogenesis, sutures, wounds and injuries, cornea
Trans. Vis. Sci. Tech.. 2021; 10(5):11. doi: https://doi.org/10.1167/tvst.10.5.11

Biochemistry and Molecular Biology September 2021

Effects of Aging on Human Meibum

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Igor A. Butovich; Tomo Suzuki
TAGS: aging, lipids, significance, meibomian gland dysfunction
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):23. doi: https://doi.org/10.1167/iovs.62.12.23

Includes: Supplemental Content

Retina September 2021

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X 7 in the Diabetic Retina

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Jin-Sang Yu; Jad Daw; Jose-Andres C. Portillo; Carlos S. Subauste
TAGS: cd40 antigens, diabetes mellitus, endothelial cells, intercellular adhesion molecule 1, retina, up-regulation (physiology), tumor necrosis factors, cytokine, diabetic retinopathy, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):22. doi: https://doi.org/10.1167/iovs.62.12.22

Retina September 2021

Impacts of Systemic Hypertension on the Macular Microvasculature in Diabetic Patients Without Clinical Diabetic Retinopathy

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Min-Woo Lee; Hyung-Moon Koo; Woo-Hyuk Lee; Jae-Hyeong Park; Young-Hoon Lee; Jung-Yeul Kim
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, hypertension, macular vasculature, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):21. doi: https://doi.org/10.1167/iovs.62.12.21

Visual Neuroscience September 2021

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

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Tian Tian; Leilei Zou; Shu Wang; Rui Liu; Hong Liu
TAGS: 3,4-dihydroxyphenylacetic acid, caviidae, dopamine, vitreous body, cues, blue light, white light, green light
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):20. doi: https://doi.org/10.1167/iovs.62.12.20

Biochemistry and Molecular Biology September 2021

Novel Insights Into Muscarinic and Purinergic Responses in Primary Cultures of Rat Lacrimal Gland Myoepithelial Cells

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Martin Dankis; Thomas Carlsson; Patrik Aronsson; Gunnar Tobin; Michael Winder
TAGS: lacrimal gland, muscarinic acetylcholine receptor, patient isolation
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):19. doi: https://doi.org/10.1167/iovs.62.12.19

Biochemistry and Molecular Biology September 2021

The Potential Role of Osteopontin in the Pathogenesis of Graves’ Ophthalmopathy

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Heng Lou; Lian-Qun Wu; Hao Wang; Rui-Li Wei; Jin-Wei Cheng
TAGS: collagen, connective tissue, cytokine, graves' ophthalmopathy, osteopontin, pathogenesis, proteins, rna, messenger, cd40 ligand, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):18. doi: https://doi.org/10.1167/iovs.62.12.18

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Novel Foveal Features Associated With Vision Impairment in Multiple Sclerosis

Impact of Structural Changes on Multifocal Electroretinography in Patients With Use of Hydroxychloroquine

Familiar size affects the perceived size and distance of real objects even with binocular vision

A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Interim Clinical Trial Results

A Deep Learning System for Automatic Assessment of Anterior Chamber Angle in Ultrasound Biomicroscopy Images

Quantitative Analysis of Eyeball Rotation During Lateral Gaze in Intermittent Exotropia: A Magnetic Resonance Imaging Study

Retinal Vascular Resistance Significantly Correlates With Visual Acuity After 1 Year of Anti-VEGF Therapy in Central Retinal Vein Occlusion

Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography

Integrating Clinical Data and Tear Proteomics to Assess Efficacy, Ocular Surface Status, and Biomarker Response After Orthokeratology Lens Wear

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

Spatially Resolved Proteomic Analysis of the Lens Extracellular Diffusion Barrier

Modeling refractive correction strategies in keratoconus

Coming of Age for the Photoreceptor Synapse

Corneal Collagen Cross-Linking Pretreatment Mitigates Injury-Induced Inflammation, Hemangiogenesis and Lymphangiogenesis In Vivo

Effects of Aging on Human Meibum

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X 7 in the Diabetic Retina

Impacts of Systemic Hypertension on the Macular Microvasculature in Diabetic Patients Without Clinical Diabetic Retinopathy

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

Novel Insights Into Muscarinic and Purinergic Responses in Primary Cultures of Rat Lacrimal Gland Myoepithelial Cells

The Potential Role of Osteopontin in the Pathogenesis of Graves’ Ophthalmopathy

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