Eye Injuries / Ocular Trauma

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Cornea December 2018

Prevention of Corneal Neovascularization by Adenovirus Encoding Human Vascular Endothelial Growth Factor Soluble Receptor (s-VEGFR1) in Lacrimal Gland

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Luis Fernando Nominato; Ana Carolina Dias; Lara Cristina Dias; Marina Zilio Fantucci; Lilian Eslaine Costa Mendes da Silva; Adriana de Andrade Murashima; Eduardo Melani Rocha
TAGS: cytokine, vascular endothelial growth factor a, gene therapy, corneal neovascularization, eye diseases, body tissue, cornea, lacrimal gland, prevention, alkalies, burns, choroidal neovascularization, adenoviruses, bodily secretions, langer-giedion syndrome, rna, messenger, adenoviral vector, normal saline
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6036-6044. doi: 10.1167/iovs.17-22322

Includes: Supplemental Content

Retina November 2018

A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse

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Ahmed S. Ibrahim; Khaled Elmasry; Ming Wan; Samer Abdulmoneim; Amber Still; Farid Khan; Abraham Khalil; Alan Saul; Md Nasrul Hoda; Mohamed Al-Shabrawey
TAGS: electroretinography, optic nerve injuries, wounds and injuries, eye, mice, optic nerve, velocity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5548-5557. doi: 10.1167/iovs.18-24773

Includes: Multimedia, Supplemental Content

Retinal Cell Biology September 2018

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

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Chloe N. Thomas; Adam M. Thompson; Eleanor McCance; Martin Berry; Ann Logan; Richard J. Blanch; Zubair Ahmed
TAGS: caspases, eye injuries, photoreceptors, retinal ganglion cells, wounds and injuries, ocular trauma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4453-4462. doi: 10.1167/iovs.18-24045

Includes: Supplemental Content

Retinal Cell Biology August 2018

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

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Kota Sato; Yukihiro Shiga; Yurika Nakagawa; Kosuke Fujita; Koji M. Nishiguchi; Hiroshi Tawarayama; Namie Murayama; Shigeto Maekawa; Takeshi Yabana; Kazuko Omodaka; Shota Katayama; Qiwei Feng; Satoru Tsuda; Toru Nakazawa
TAGS: optic nerve injuries, mice, optic nerve, retina, crispr
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3943-3951. doi: 10.1167/iovs.18-23784

Includes: Supplemental Content

Articles June 2018

Mechanical Evaluation of Retinal Damage Associated With Blunt Craniomaxillofacial Trauma: A Simulation Analysis

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Xiaoqi Geng; Xiaoyu Liu; Wei Wei; Yawei Wang; Lizhen Wang; Kinon Chen; Hongqiang Huo; Yuanjie Zhu; Yubo Fan
TAGS: cranium, wounds and injuries, eye
Trans. Vis. Sci. Tech.. 2018; 7(3):16. doi: 10.1167/tvst.7.3.16

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology June 2018

Tumor Necrosis Factor Inhibition in the Acute Management of Traumatic Optic Neuropathy

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Brian C. Tse; Galina Dvoriantchikova; Wensi Tao; Ryan A. Gallo; John Y. Lee; Steven Pappas; Roberta Brambilla; Dmitry Ivanov; David T. Tse; Daniel Pelaez
TAGS: tumor necrosis factors, etanercept, optic nerve injuries, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2905-2912. doi: 10.1167/iovs.18-24431

Cornea April 2018

Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization

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Mingjun Tang; Ying Yang; Jingzhi Yu; Jin Qiu; Pei Chen; Yihui Wu; Qiyun Wang; Zhuojun Xu; Jian Ge; Keming Yu; Jing Zhuang
TAGS: alkalies, burns, choroidal neovascularization, corneal neovascularization, cxcr4 receptors, mice
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2133-2141. doi: 10.1167/iovs.17-23712

Includes: Supplemental Content

Retinal Cell Biology February 2018

Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity

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Lynn Calvin Shaw; Sergio Li Calzi; Nan Li; Leni Moldovan; Nilanjana Sengupta-Caballero; Judith Lindsey Quigley; Mircea Ivan; Bokkyoo Jun; Nicolas G. Bazan; Michael Edwin Boulton; Julia Busik; Josef Neu; Maria B. Grant
TAGS: dipeptides, docosahexaenoic acids, neovascularization, pathologic, retinopathy of prematurity, mice, injury of retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):858-869. doi: 10.1167/iovs.17-23034

Glaucoma December 2017

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

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Robert W. Nickells; Heather M. Schmitt; Margaret E. Maes; Cassandra L. Schlamp
TAGS: optic nerve injuries, eye, mice, optic nerve, retina
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6091-6104. doi: 10.1167/iovs.17-22634

Includes: Supplemental Content

Retinal Cell Biology September 2017

Edaravone Prevents Retinal Degeneration in Adult Mice Following Optic Nerve Injury

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Goichi Akiyama; Yuriko Azuchi; Xiaoli Guo; Takahiko Noro; Atsuko Kimura; Chikako Harada; Kazuhiko Namekata; Takayuki Harada
TAGS: adult, optic nerve injuries, retinal degeneration, mice, edaravone
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4908-4914. doi: 10.1167/iovs.17-22250

Retina September 2017

Comparison of Continuous-Wave and Micropulse Modulation in Retinal Laser Therapy

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Jenny Wang; Yi Quan; Roopa Dalal; Daniel Palanker
TAGS: computer simulation, lasers, oryctolagus cuniculus, body tissue, choroid, retina, laser therapy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4722-4732. doi: 10.1167/iovs.17-21610

Includes: Multimedia, Supplemental Content

Cornea September 2017

Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation

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Tarsis F. Gesteira; Mingxia Sun; Yvette M. Coulson-Thomas; Yu Yamaguchi; Lung-Kun Yeh; Vincent Hascall; Vivien J. Coulson-Thomas
TAGS: debridement, stem cells, epithelium, alkalies, burns, wounds and injuries, cornea, mice, epithelial cells, hyaluronan, stem cell niche
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4407-4421. doi: 10.1167/iovs.17-22326

Includes: Supplemental Content

Cornea July 2017

Retinoic Acid Engineered Amniotic Membrane Used as Graft or Homogenate: Positive Effects on Corneal Alkali Burns

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Romain Joubert; Estelle Daniel; Nicolas Bonnin; Aurélie Comptour; Christelle Gross; Corinne Belville; Frédéric Chiambaretta; Loïc Blanchon; Vincent Sapin
TAGS: ulcer, alkalies, amnion, burns, tissue transplants, tretinoin, cornea, corneal burn
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3513-3518. doi: 10.1167/iovs.17-21810

Includes: Supplemental Content

Cornea March 2017

Topical Cryopreserved Amniotic Membrane and Umbilical Cord Eye Drops Promote Re-Epithelialization in a Murine Corneal Abrasion Model

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Sean Tighe; Hamid-Reza Moein; Lorraine Chua; Anny Cheng; Pedram Hamrah; Scheffer C. G. Tseng
TAGS: corneal abrasions, epithelium, amnion, cryopreservation, umbilical cord, cornea, mice, eyedrops, epithelialization, abrasion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1586-1593. doi: 10.1167/iovs.16-20834

Cornea January 2017

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye

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Chengxin Zhou; Marie-Claude Robert; Vassiliki Kapoulea; Fengyang Lei; Anna M. Stagner; Frederick A. Jakobiec; Claes H. Dohlman; Eleftherios I. Paschalis
TAGS: tumor necrosis factors, alkalies, burns, oryctolagus cuniculus, cornea, eye, retina, infliximab, subconjunctival route
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):96-105. doi: 10.1167/iovs.16-20339

Includes: Supplemental Content

Retina August 2016

Sildenafil Improves Functional and Structural Outcome of Retinal Injury Following Term Neonatal Hypoxia-Ischemia

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Suna Jung; Aaron Johnstone; Zehra Khoja; Emmanouil Rampakakis; Pierre Lachapelle; Pia Wintermark
TAGS: ischemia, sildenafil, hypoxia, newborn, retina, injury of retina
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4306-4314. doi: 10.1167/iovs.16-19385

Nantotechnology and Regenerative Medicine June 2016

Dexamethasone Drug Eluting Nanowafers Control Inflammation in Alkali-Burned Corneas Associated With Dry Eye

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Fang Bian; Crystal S. Shin; Changjun Wang; Stephen C. Pflugfelder; Ghanashyam Acharya; Cintia S. De Paiva
TAGS: inflammation, dexamethasone, alkalies, burns, dry eye syndromes, eye burns, cornea, mice, stress, eye inflammation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3222-3230. doi: 10.1167/iovs.16-19074

Retinal Cell Biology April 2016

Antiviral Drug Ganciclovir Is a Potent Inhibitor of the Proliferation of Müller Glia–Derived Progenitors During Zebrafish Retinal Regeneration

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Shuqiang Zhang; Zhaoxia Mu; Chunjiao He; Minmin Zhou; Dong Liu; Xiao-Feng Zhao; Daniel Goldman; Hui Xu
TAGS: anaplasia, antiviral agents, bromodeoxyuridine, fluorescent antibody technique, ganciclovir, microglia, neuroglia, wounds and injuries, zebrafish, eye, retina, injury of retina, painful bladder syndrome
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1991-2000. doi: 10.1167/iovs.15-18669

Includes: Supplemental Content

Retinal Cell Biology April 2016

A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury

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Alex Woodell; Bryan W. Jones; Tucker Williamson; Gloriane Schnabolk; Stephen Tomlinson; Carl Atkinson; Bärbel Rohrer
TAGS: familial hypercholesterolemia, biological response modifiers, complement pathway, alternative, eye injuries, recovery of function, smoke, mice, family history
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1728-1737. doi: 10.1167/iovs.15-18471

Cornea December 2015

VesselJ: A New Tool for Semiautomatic Measurement of Corneal Neovascularization

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Alessandro Rabiolo; Fabio Bignami; Paolo Rama; Giulio Ferrari
TAGS: alkalies, burns, choroidal neovascularization, corneal neovascularization, sutures, cornea, lymphatic vessel, copy number polymorphism
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8199-8206. doi: 10.1167/iovs.15-17098

Includes: Multimedia, Supplemental Content

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Prevention of Corneal Neovascularization by Adenovirus Encoding Human Vascular Endothelial Growth Factor Soluble Receptor (s-VEGFR1) in Lacrimal Gland

A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

Mechanical Evaluation of Retinal Damage Associated With Blunt Craniomaxillofacial Trauma: A Simulation Analysis

Tumor Necrosis Factor Inhibition in the Acute Management of Traumatic Optic Neuropathy

Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization

Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity

AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

Edaravone Prevents Retinal Degeneration in Adult Mice Following Optic Nerve Injury

Comparison of Continuous-Wave and Micropulse Modulation in Retinal Laser Therapy

Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation

Retinoic Acid Engineered Amniotic Membrane Used as Graft or Homogenate: Positive Effects on Corneal Alkali Burns

Topical Cryopreserved Amniotic Membrane and Umbilical Cord Eye Drops Promote Re-Epithelialization in a Murine Corneal Abrasion Model

Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye

Sildenafil Improves Functional and Structural Outcome of Retinal Injury Following Term Neonatal Hypoxia-Ischemia

Dexamethasone Drug Eluting Nanowafers Control Inflammation in Alkali-Burned Corneas Associated With Dry Eye

Antiviral Drug Ganciclovir Is a Potent Inhibitor of the Proliferation of Müller Glia–Derived Progenitors During Zebrafish Retinal Regeneration

A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury

VesselJ: A New Tool for Semiautomatic Measurement of Corneal Neovascularization

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