Genetics

Showing 1 – 20 of 6220

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Lens December 2024

Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells

PDF

Cong Fan; Yu Yang; Mengling You; Zhuo Chen; Jian Jiang
TAGS: epithelial to mesenchymal transition, inflammation, lens epithelial cell, oxidative stress, surgical procedures, operative, western blotting, mitogen-activated protein kinases, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):17. https://doi.org/10.1167/iovs.65.14.17

Includes: Supplemental Content

Genetics December 2024

Linking Iris Cis -Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics

PDF

Jiaying Li; Yun Chen; Wenbin Wang; Ye Zhang; Guangsong Su; Sean K. Wang; Yuanyuan Zhang; Yilong Yao; Shen Wu; Wange Lu; Kunlin Zhang; Chunyan Qiao; Shuning Li; Hengtong Li; Ching-Yu Cheng; Yuwen Liu; Ningli Wang
TAGS: angle closure glaucoma, iris, pathogenesis, enhancer of transcription, diagnostic imaging, chromatin, alleles, multiomics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):18. https://doi.org/10.1167/iovs.65.14.18

Includes: Supplemental Content

Retina December 2024

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

PDF

Monica Ardon; Lily Nguyen; Rui Chen; Jeffrey Rogers; Tim Stout; Sara Thomasy; Ala Moshiri
TAGS: disease progression, electroretinography, homozygote, infant, mutation, primates, retinal cone, macaca, adult, heterozygote
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):16. https://doi.org/10.1167/iovs.65.14.16

Includes: Supplemental Content

Cornea December 2024

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

PDF

Xin Zuo; Hao Zeng; Xue Yang; Dalian He; Bowen Wang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, loeys-dietz syndrome, proteins, stress, western blotting, autophagy, lipid peroxidation, lysosomes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):12. https://doi.org/10.1167/iovs.65.14.12

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics December 2024

Retinal Sensitivity in Comparison to Cone Density in Choroideremia

PDF

Niamh Wynne; Yu You Jiang; Tomas S. Aleman; Jessica I. W. Morgan
TAGS: atrophic condition of skin, choroideremia, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):6. https://doi.org/10.1167/iovs.65.14.6

Retina December 2024

Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies

PDF

Melissa A. Calton; Roxanne H. Croze; Christian Burns; Ghezal Beliakoff; Tandis Vazin; Paul Szymanski; Christopher Schmitt; Austin Klein; Meredith Leong; Melissa Quezada; Jenny Holt; Gabe Bolender; Katherine Barglow; Devi Khoday; Thomas Mason; Katherine Delaria; Mohammad Hassanipour; Melissa Kotterman; Arshad M. Khanani; David Schaffer; Peter Francis; David Kirn
TAGS: eye, gene therapy, genetics, retinal diseases, transgenes, spatial vectors, choroidal neovascularization, capsid, primates, disease vectors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):1. https://doi.org/10.1167/iovs.65.14.1

Includes: Supplemental Content

Article November 2024

The choices hidden in photography

PDF

Aaron Hertzmann
TAGS: photography, color, perception
Journal of Vision. 2024; 22(11):10. https://doi.org/10.1167/jov.22.11.10

Anatomy and Pathology/Oncology November 2024

Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research

PDF

Lauren A. Dalvin; Cynthia M. Andrews-Pfannkoch; David R. Miley; Tara L. Hogenson; Samantha A. Erickson; Shivani Malpotra; Kjersten J. Anderson; Mohammed E. Omer; Luciana L. Almada; Cheng Zhang; Hu Li; Diva R. Salomao; Carol L. Shields; Sara E. Lally; Rachel M. Malsch; James A. Armitage; Heather L. Holmes; Michael F. Romero; Michael P. Fautsch; Svetomir N. Markovic; Martin E. Fernandez-Zapico
TAGS: intraocular melanoma, neoplasms, organoids, translational research, immunohistochemistry, bap1 gene, transplantation, heterologous, atac trial
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):60. https://doi.org/10.1167/iovs.65.13.60

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

PDF

Amandeep Singh Josan; Laura Jayne Taylor; Kanmin Xue; Jasmina Cehajic-Kapetanovic; Robert Edward MacLaren
TAGS: choroideremia, functional measures, outcome measures, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):58. https://doi.org/10.1167/iovs.65.13.58

Includes: Supplemental Content

Retinal Cell Biology November 2024

Small Extracellular Vesicle-Associated MiRNAs in Polarized Retinal Pigmented Epithelium

PDF

Belinda J. Hernandez; Madison Strain; Maria Fernanda Suarez; W. Daniel Stamer; Allison Ashley-Koch; Yutao Liu; Mikael Klingeborn; Catherine Bowes Rickman
TAGS: micrornas, patient isolation, social isolation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):57. https://doi.org/10.1167/iovs.65.13.57

Includes: Supplemental Content

Cornea November 2024

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

PDF

Yang Huang; Lijun Wang; Haiying Jin
TAGS: bilirubin, cornea, dry eye syndromes, mice, mitophagy, nadph oxidase 4, nanoparticles, ocular surfaces, pink1 gene, nitric oxide synthase
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):55. https://doi.org/10.1167/iovs.65.13.55

Includes: Supplemental Content

Genetics November 2024

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

PDF

Shlomit Jaskoll; Adi Kramer; Sarah Elbaz-Hayoun; Batya Rinsky; Chiara M. Eandi; Michelle Grunin; Yahel Shwartz; Liran Tiosano; Iris M. Heid; Thomas Winkler; Itay Chowers
TAGS: adult, age-related macular degeneration, genetics, vitelliform dystrophy, complement system proteins, complement activation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):53. https://doi.org/10.1167/iovs.65.13.53

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

PDF

Jordan Loeliger; Romain Lhotte; Sahar Gelfman; Eli A. Stahl; Dominique Monnet; Valentin Clichet; Linda Imikirene; Souhila Kecili; Jean-Luc Taupin; Thierry Tabary; Jacques H. M. Cohen; Antoine P. Brézin
TAGS: alleles, disease susceptibility, hla-a antigens, homozygote, human leukocyte antigens, vitiliginous chorioretinitis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):47. https://doi.org/10.1167/iovs.65.13.47

Includes: Supplemental Content

Artificial Intelligence November 2024

Associations of Metabolically Healthy Obesity and Retinal Age Gap

PDF

Xiaomin Zeng; Ruiye Chen; Gabriella Bulloch; Qingsheng Peng; Ching-Yu Cheng; Mingguang He; Honghua Yu; Zhuoting Zhu
TAGS: obesity, obesity, metabolically benign, phenotype, body mass index procedure, body weight
Trans. Vis. Sci. Tech.. 2024; 13(11):26. https://doi.org/10.1167/tvst.13.11.26

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

PDF

Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

PDF

Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2024

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

PDF

Charkira C. Patrick; Elisa Roztocil; Farha Husain; Steven E. Feldon; Collynn F. Woeller
TAGS: aryl hydrocarbon receptor, fibroblasts, graves' ophthalmopathy, ligands, signal transduction, tapinarof, platelet-derived growth factor, thymidylate synthase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):40. https://doi.org/10.1167/iovs.65.13.40

Includes: Supplemental Content

Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

PDF

Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

Low Vision Rehabilitation November 2024

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

PDF

Jing Cong; Xinyuan Wu; Chunqiong Dong; Jing Wang; Chenli Feng; Gechun Wang; Yiting Wu; Gislin Dagnelie; Jinhui Dai; Yuanzhi Yuan
TAGS: chinese (other dialects), chinese people, psychometrics, questionnaires, vision, rasch model
Trans. Vis. Sci. Tech.. 2024; 13(11):20. https://doi.org/10.1167/tvst.13.11.20

Includes: Supplemental Content

Cornea November 2024

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

PDF

Xiaowei Yang; Xingwu Zhong; Haotian Lin; Andrew J.W. Huang; Lixing W. Reneker
TAGS: atrophy, epithelium, fgfr2 gene, meibomian gland dysfunction, mice, tamoxifen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):36. https://doi.org/10.1167/iovs.65.13.36

Includes: Supplemental Content

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells

Linking Iris Cis -Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

Retinal Sensitivity in Comparison to Cone Density in Choroideremia

Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies

The choices hidden in photography

Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

Small Extracellular Vesicle-Associated MiRNAs in Polarized Retinal Pigmented Epithelium

cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated Mitophagy

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

Associations of Metabolically Healthy Obesity and Retinal Age Gap

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Tapinarof, an Aryl Hydrocarbon Receptor Ligand, Mitigates Fibroblast Activation in Thyroid Eye Disease: Implications for Novel Therapy

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

Development and Psychometric Assessment of a Chinese Version of the Ultra-Low Vision Visual Functioning Questionnaire-50

Deletion of Fgfr2 in Ductal Basal Epithelium With Tamoxifen Induces Obstructive Meibomian Gland Dysfunction

This feature is available to authenticated users only.

Genetics

To View More...

You must be signed into an individual account to use this feature.