Glaucoma

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Glaucoma September 2018

Thin Lamina Cribrosa Beams Have Different Collagen Microstructure Than Thick Beams

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Bryn L. Brazile; Yi Hua; Ning-Jiun Jan; Jacob Wallace; Alexandra Gogola; Ian A. Sigal
TAGS: collagen, eye, cribriform plate
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4653-4661. doi: 10.1167/iovs.18-24763

Includes: Supplemental Content

Glaucoma September 2018

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

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Larry N. Singh; Jonathan G. Crowston; M. Isabel G. Lopez Sanchez; Nicole J. Van Bergen; Lisa S. Kearns; Alex W. Hewitt; Seyhan Yazar; David A. Mackey; Douglas C. Wallace; Ian A. Trounce
TAGS: glaucoma, disease susceptibility, open-angle glaucoma, dna, mitochondrial
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4598-4602. doi: 10.1167/iovs.18-25085

Includes: Supplemental Content

Glaucoma September 2018

Microvascular Changes in Peripapillary and Optic Nerve Head Tissues After Trabeculectomy in Primary Open-Angle Glaucoma

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Ji-Ah Kim; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari
TAGS: open-angle glaucoma, optic disk, body tissue, eye, intraocular pressure, microvascular network, trabeculectomy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4614-4621. doi: 10.1167/iovs.18-25038

Articles September 2018

Motility Changes and Diplopia After Baerveldt Glaucoma Drainage Device Implantation or After Trabeculectomy

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Esma Islamaj; Caroline P. Jordaan-Kuip; Koen A. Vermeer; Hans G. Lemij; Peter W.T. de Waard
TAGS: diplopia, cell motility, glaucoma drainage implants, surgical procedures, operative, trabeculectomy, implantation procedure
Trans. Vis. Sci. Tech.. 2018; 7(5):7. doi: 10.1167/tvst.7.5.7

Articles September 2018

Pattern Electroretinogram Detects Localized Glaucoma Defects

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Tommaso Salgarello; Andrea Giudiceandrea; Luigi Calandriello; Dario Marangoni; Alberto Colotto; Aldo Caporossi; Benedetto Falsini
TAGS: glaucoma, electroretinography
Trans. Vis. Sci. Tech.. 2018; 7(5):6. doi: 10.1167/tvst.7.5.6

Physiology and Pharmacology September 2018

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

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John E. Markert; Jessica V. Jasien; Daniel C. Turner; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: perfusion, primates, telemetry, eye, intraocular pressure, mean arterial pressure, impulse
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4496-4505. doi: 10.1167/iovs.18-23802

Includes: Multimedia, Supplemental Content

Glaucoma September 2018

Characteristics of the Corneal Endothelium Across the Primary Angle Closure Disease Spectrum

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Sushma Verma; Monisha E. Nongpiur; Rahat Husain; Tina T. Wong; Pui Yi Boey; Desmond Quek; Shamira A. Perera; Tin Aung
TAGS: endothelial cells, endothelium, corneal endothelium, cornea, eye, primary angle closure suspect
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4525-4530. doi: 10.1167/iovs.18-24939

Glaucoma September 2018

Effect of Resveratrol on Sirtuins, OPA1, and Fis1 Expression in Adult Zebrafish Retina

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Weiwei Sheng; Ye Lu; Feng Mei; Ning Wang; Zhi-Zhi Liu; Ying-Ying Han; Han-Tsing Wang; Suqi Zou; Hong Xu; Xu Zhang
TAGS: polymerase chain reaction, mitochondria, adult, genes, n-methylaspartate, zebrafish, retina, resveratrol, sirtuins, optic atrophy, autosomal dominant
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4542-4551. doi: 10.1167/iovs.18-24539

Includes: Supplemental Content

Glaucoma September 2018

Macular Pigment and Visual Function in Patients With Glaucoma: The San Diego Macular Pigment Study

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Fábio B. Daga; Nara G. Ogata; Felipe A. Medeiros; Rachel Moran; Jeffrey Morris; Linda M. Zangwill; Robert N. Weinreb; John M. Nolan
TAGS: diet, glaucoma, carotenoids, vision, macular pigment
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4471-4476. doi: 10.1167/iovs.18-24170

Biochemistry and Molecular Biology September 2018

A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency

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Stéphanie Leruez; Alexandre Marill; Thomas Bresson; Grégoire de Saint Martin; Adrien Buisset; Jeanne Muller; Lydie Tessier; Cédric Gadras; Christophe Verny; Philippe Gohier; Patrizia Amati-Bonneau; Guy Lenaers; Dominique Bonneau; Gilles Simard; Dan Milea; Vincent Procaccio; Pascal Reynier; Juan Manuel Chao de la Barca
TAGS: aging, mitochondria, glaucoma, open-angle glaucoma, polyamines, pathophysiology, elderly, metabolites, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4355-4361. doi: 10.1167/iovs.18-24938

Includes: Supplemental Content

Articles September 2018

Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma

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Jack Phu; Sieu K. Khuu; Bang V. Bui; Michael Kalloniatis
TAGS: glaucoma, cohort studies, pattern recognition, early diagnosis
Trans. Vis. Sci. Tech.. 2018; 7(5):3. doi: 10.1167/tvst.7.5.3

Includes: Supplemental Content

Articles August 2018

Comparison of Visual Field Point-Wise Event-Based and Global Trend-Based Analysis for Detecting Glaucomatous Progression

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Zhichao Wu; Felipe A. Medeiros
TAGS: glaucoma, visual fields, eye, specificity of diagnostic test, trend
Trans. Vis. Sci. Tech.. 2018; 7(4):20. doi: 10.1167/tvst.7.4.20

Articles August 2018

The Relationship Between Bruch's Membrane Opening-Minimum Rim Width and Retinal Nerve Fiber Layer Thickness and a New Index Using a Neural Network

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Keunheung Park; Jinmi Kim; Jiwoong Lee
TAGS: glaucoma, bruch's basal membrane, visual fields, retinal nerve fiber layer, stick dosage form
Trans. Vis. Sci. Tech.. 2018; 7(4):14. doi: 10.1167/tvst.7.4.14

Articles August 2018

Parent-Child Agreement on Health-Related Quality of Life in Congenital Glaucoma

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Vijaya K. Gothwal; Seelam Bharani; Anil K. Mandal
TAGS: child, glaucoma, congenital, parent, questionnaires, health-related quality of life
Trans. Vis. Sci. Tech.. 2018; 7(4):15. doi: 10.1167/tvst.7.4.15

Glaucoma August 2018

Increased Iris Stiffness in Patients With a History of Angle-Closure Glaucoma: An Image-Based Inverse Modeling Analysis

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Anup Dev Pant; Priyanka Gogte; Vanita Pathak-Ray; Syril K. Dorairaj; Rouzbeh Amini
TAGS: medical history, iris, immune reconstitution inflammatory syndrome, angle closure glaucoma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4134-4142. doi: 10.1167/iovs.18-24327

Anatomy and Pathology/Oncology August 2018

The Impact of Choroidal Swelling on Optic Nerve Head Deformation

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Andrew J. Feola; Emily S. Nelson; Jerry Myers; C. Ross Ethier; Brian C. Samuels
TAGS: edema, optic disk, body tissue, choroid
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4172-4181. doi: 10.1167/iovs.18-24463

Includes: Supplemental Content

Glaucoma August 2018

An Optical Coherence Tomography Angiography Study of the Relationship Between Foveal Avascular Zone Size and Retinal Vessel Density

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Junki Kwon; Jaewan Choi; Joong Won Shin; Jiyun Lee; Michael S. Kook
TAGS: angiogram, glaucoma, fovea centralis, respiratory care units, retinal vessels, vindesine, visual fields, eye, optical coherence tomography, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4143-4153. doi: 10.1167/iovs.18-24168

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology August 2018

Retinal Microvascular Impairment in the Early Stages of Parkinson's Disease

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William Robert Kwapong; Hua Ye; Chenlei Peng; Xiran Zhuang; Jianhua Wang; Meixiao Shen; Fan Lu
TAGS: parkinson disease, blood capillaries, eye, retina, impairment, microvascular network, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4115-4122. doi: 10.1167/iovs.17-23230

Glaucoma August 2018

Ultrastructural Morphology of the Optic Nerve Head in Aged and Glaucomatous Mice

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Ying Zhu; Anthony C. Pappas; Rui Wang; Philip Seifert; Daniel Sun; Tatjana C. Jakobs
TAGS: mitochondria, glaucoma, axon, microspheres, neurons, optic disk, mice, optic nerve, morphology, language morphology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3984-3996. doi: 10.1167/iovs.18-23885

Includes: Supplemental Content

Glaucoma August 2018

Modeling the Origin of the Ocular Pulse and Its Impact on the Optic Nerve Head

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Yuejiao Jin; Xiaofei Wang; Liang Zhang; Jost B. Jonas; Tin Aung; Leopold Schmetterer; Michaël J. A. Girard
TAGS: diastole, optic disk, systole, intraocular pressure, sclera, cardiac cycle, pulse volume
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3997-4010. doi: 10.1167/iovs.17-23454

Includes: Supplemental Content

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Thin Lamina Cribrosa Beams Have Different Collagen Microstructure Than Thick Beams

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

Microvascular Changes in Peripapillary and Optic Nerve Head Tissues After Trabeculectomy in Primary Open-Angle Glaucoma

Motility Changes and Diplopia After Baerveldt Glaucoma Drainage Device Implantation or After Trabeculectomy

Pattern Electroretinogram Detects Localized Glaucoma Defects

IOP, IOP Transient Impulse, Ocular Perfusion Pressure, and Mean Arterial Pressure Relationships in Nonhuman Primates Instrumented With Telemetry

Characteristics of the Corneal Endothelium Across the Primary Angle Closure Disease Spectrum

Effect of Resveratrol on Sirtuins, OPA1, and Fis1 Expression in Adult Zebrafish Retina

Macular Pigment and Visual Function in Patients With Glaucoma: The San Diego Macular Pigment Study

A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency

Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma

Comparison of Visual Field Point-Wise Event-Based and Global Trend-Based Analysis for Detecting Glaucomatous Progression

The Relationship Between Bruch's Membrane Opening-Minimum Rim Width and Retinal Nerve Fiber Layer Thickness and a New Index Using a Neural Network

Parent-Child Agreement on Health-Related Quality of Life in Congenital Glaucoma

Increased Iris Stiffness in Patients With a History of Angle-Closure Glaucoma: An Image-Based Inverse Modeling Analysis

The Impact of Choroidal Swelling on Optic Nerve Head Deformation

An Optical Coherence Tomography Angiography Study of the Relationship Between Foveal Avascular Zone Size and Retinal Vessel Density

Retinal Microvascular Impairment in the Early Stages of Parkinson's Disease

Ultrastructural Morphology of the Optic Nerve Head in Aged and Glaucomatous Mice

Modeling the Origin of the Ocular Pulse and Its Impact on the Optic Nerve Head

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