Glaucoma

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Glaucoma March 2023

Progression of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry

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Emmanouil Tsamis; Sol La Bruna; Anvit Rai; Ari Leshno; Jennifer Grossman; George Cioffi; Jeffrey M. Liebmann; Carlos Gustavo De Moraes; Donald C. Hood
TAGS: eye, glaucoma, optical coherence tomography, perimetry, specificity of diagnostic test, trend
Trans. Vis. Sci. Tech.. 2023; 12(3):19. doi: https://doi.org/10.1167/tvst.12.3.19

Includes: Supplemental Content

Physiology and Pharmacology March 2023

Differences in Outflow Facility Between Angiographically Identified High- Versus Low-Flow Regions of the Conventional Outflow Pathways in Porcine Eyes

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Clemens A. Strohmaier; Fiona S. McDonnell; Xiaowei Zhang; Daniel Wanderer; W. Daniel Stamer; Robert N. Weinreb; Alex S. Huang
TAGS: eye, fluid flow, suidae, perfusion
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):29. doi: https://doi.org/10.1167/iovs.64.3.29

Includes: Supplemental Content

Cornea & External Disease March 2023

Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study

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Mitchell A. Kirby; Gabriel Regnault; Ivan Pelivanov; Matthew O'Donnell; Ruikang K. Wang; Tueng T. Shen
TAGS: acoustics, cornea, elasticity imaging techniques, microbiology procedures, oryctolagus cuniculus, elasticity, optics, intraocular pressure
Trans. Vis. Sci. Tech.. 2023; 12(3):15. doi: https://doi.org/10.1167/tvst.12.3.15

Includes: Supplemental Content

Neuro-ophthalmology March 2023

Discriminating Between Compressive Optic Neuropathy With Glaucoma-Like Cupping and Glaucomatous Optic Neuropathy Using OCT and OCTA

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Kun Lei; Yuanzhen Qu; Yang Tang; Wen Lu; Heng Zhao; Meizi Wang; Liu Yang; Xuxiang Zhang
TAGS: cupping therapy, glaucoma, optic nerve compression, optic nerve disorders, eye
Trans. Vis. Sci. Tech.. 2023; 12(3):11. doi: https://doi.org/10.1167/tvst.12.3.11

Includes: Supplemental Content

Artificial Intelligence March 2023

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

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Vidisha Goyal; A. Thomas Read; Matthew D. Ritch; Bailey G. Hannon; Gabriela Sanchez Rodriguez; Dillon M. Brown; Andrew J. Feola; Adam Hedberg-Buenz; Grant A. Cull; Juan Reynaud; Mona K. Garvin; Michael G. Anderson; Claude F. Burgoyne; C. Ross Ethier
TAGS: axon, datasets, learning
Trans. Vis. Sci. Tech.. 2023; 12(3):9. doi: https://doi.org/10.1167/tvst.12.3.9

Includes: Supplemental Content

Glaucoma March 2023

Morphometric Analysis of Retinal Ganglion Cell Axons in Normal and Glaucomatous Brown Norway Rats Optic Nerves

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Vidisha Goyal; A. Thomas Read; Dillon M. Brown; Luke Brawer; Kaitlyn Bateh; Bailey G. Hannon; Andrew J. Feola; C. Ross Ethier
TAGS: axon, cohort studies, eye, glaucoma, hypertension, myelin sheath, optic nerve, rats, retinal ganglion cells
Trans. Vis. Sci. Tech.. 2023; 12(3):8. doi: https://doi.org/10.1167/tvst.12.3.8

Includes: Supplemental Content

Glaucoma March 2023

Choroidal Microvasculature Dropout in the Absence of Parapapillary Atrophy in POAG

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Eun Ji Lee; Ji Eun Song; Hye Seong Hwang; Jeong-Ah Kim; Seung Hyen Lee; Tae-Woo Kim
TAGS: atrophy, eye, glaucoma, microvascular network, open-angle glaucoma, optic disk, perfusion, common cold
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):21. doi: https://doi.org/10.1167/iovs.64.3.21

Glaucoma March 2023

Proposed Mechanism of Long-Term Intraocular Pressure Lowering With the Bimatoprost Implant

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W. Daniel Stamer; Kristin M. Perkumas; Min H. Kang; Mohammed Dibas; Michael R. Robinson; Douglas J. Rhee
TAGS: bimatoprost, implants, intraocular pressure, gene expression, interstitial collagenase
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):15. doi: https://doi.org/10.1167/iovs.64.3.15

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2023

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

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Ella C. Berry; Henry N. Marshall; Sean Mullany; Santiago Diaz Torres; Joshua Schmidt; Daniel Thomson; Lachlan S. W. Knight; Georgina L. Hollitt; Ayub Qassim; Bronwyn Ridge; Angela Schulz; Mark M. Hassall; Thi Thi Nguyen; Stewart Lake; Richard A. Mills; Ashish Agar; Anna Galanopoulos; John Landers; Paul R. Healey; Stuart L. Graham; Alex W. Hewitt; Stuart MacGregor; Robert J. Casson; Owen M. Siggs; Jamie E. Craig
TAGS: cohort studies, physical activity, biobanks
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):11. doi: https://doi.org/10.1167/iovs.64.3.11

Includes: Supplemental Content

Glaucoma March 2023

24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression

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Thibaut Gaboriau; Remi Dubois; Boris Foucque; Florence Malet; Cedric Schweitzer
TAGS: contact lenses, glaucoma, intraocular pressure, sensor, visual fields
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):3. doi: https://doi.org/10.1167/iovs.64.3.3

Glaucoma March 2023

Development of a Novel Valve-Controlled Drug-Elutable Microstent for Microinvasive Glaucoma Surgery: In Vitro and Preclinical In Vivo Studies

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Stefan Siewert; Sabine Kischkel; Andreas Brietzke; Ludmila Kinzel; Tobias Lindner; Ulf Hinze; Boris Chichkov; Wolfram Schmidt; Michael Stiehm; Niels Grabow; Rudolf F. Guthoff; Klaus-Peter Schmitz; Thomas Stahnke
TAGS: anterior chamber of eye, eye, fluid flow, glaucoma, glaucoma microstents, glaucoma surgery, implantation procedure, intraocular pressure, oryctolagus cuniculus, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2023; 12(3):4. doi: https://doi.org/10.1167/tvst.12.3.4

Includes: Supplemental Content

Glaucoma February 2023

ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts

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Jack E. Teplitsky; Anastasiya Vinokurtseva; James J. Armstrong; James Denstedt; Hong Liu; Cindy M. L. Hutnik
TAGS: cicatrix, collagen, cytotoxicity, fibroblasts, glaucoma surgery, mitomycin, proteins, tenon's capsule, fibrosis
Trans. Vis. Sci. Tech.. 2023; 12(2):31. doi: https://doi.org/10.1167/tvst.12.2.31

Includes: Supplemental Content

Glaucoma February 2023

Longitudinal Signal-to-Noise Ratio of Perimetry at Different Severities of Glaucoma

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Stuart K. Gardiner
TAGS: glaucoma, perimetry, signal-to-noise ratio, eye
Trans. Vis. Sci. Tech.. 2023; 12(2):30. doi: https://doi.org/10.1167/tvst.12.2.30

Includes: Supplemental Content

Artificial Intelligence February 2023

Medical Application of Geometric Deep Learning for the Diagnosis of Glaucoma

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Alexandre H. Thiéry; Fabian Braeu; Tin A. Tun; Tin Aung; Michaël J. A. Girard
TAGS: deep learning, glaucoma
Trans. Vis. Sci. Tech.. 2023; 12(2):23. doi: https://doi.org/10.1167/tvst.12.2.23

Glaucoma February 2023

Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes

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Jack Quach; Glen P. Sharpe; Shaban Demirel; Christopher A. Girkin; Christian Y. Mardin; Alexander F. Scheuerle; Claude F. Burgoyne; Balwantray C. Chauhan; Jayme R. Vianna
TAGS: eye, retinal nerve fiber layer, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):17. doi: https://doi.org/10.1167/iovs.64.2.17

Glaucoma February 2023

Genetic Associations Between Smoking- and Glaucoma-Related Traits

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Jessica H. Tran; Kelsey V. Stuart; Victor de Vries; Joëlle E. Vergroesen; Clara C. Cousins; Pirro G. Hysi; Ron Do; Ghislain Rocheleau; Jae H. Kang; Janey L. Wiggs; Stuart MacGregor; Anthony P. Khawaja; David A. Mackey; Caroline C. W. Klaver; Wishal D. Ramdas; Louis R. Pasquale; for the UK Biobank Eye and Vision Consortium, and for the International Glaucoma Genetics Consortium
TAGS: genetics, glaucoma, smoking
Trans. Vis. Sci. Tech.. 2023; 12(2):20. doi: https://doi.org/10.1167/tvst.12.2.20

Includes: Supplemental Content

Retina February 2023

Beneficial and Detrimental Pressure-Related Effects on Inner Neurons in the Adult Porcine In Vitro Retina

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Frida Svare; Fredrik Ghosh
TAGS: adult, immunohistochemistry, retina, suidae, retinal bipolar cells, neurons, rod photoreceptors, ganglia
Trans. Vis. Sci. Tech.. 2023; 12(2):19. doi: https://doi.org/10.1167/tvst.12.2.19

Data Science February 2023

PyVisualFields: A Python Package for Visual Field Analysis

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Mohammad Eslami; Saber Kazeminasab; Vishal Sharma; Yangjiani Li; Mojtaba Fazli; Mengyu Wang; Nazlee Zebardast; Tobias Elze
TAGS: libraries, software, visual fields, languages
Trans. Vis. Sci. Tech.. 2023; 12(2):6. doi: https://doi.org/10.1167/tvst.12.2.6

Glaucoma February 2023

The Effects of Negative Periocular Pressure on Biomechanics of the Optic Nerve Head and Cornea: A Computational Modeling Study

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Babak N. Safa; Adam Bleeker; John P. Berdahl; C. Ross Ethier
TAGS: biomechanics, body tissue, cornea, intraocular pressure, optic disk, computer simulation, eye
Trans. Vis. Sci. Tech.. 2023; 12(2):5. doi: https://doi.org/10.1167/tvst.12.2.5

Includes: Supplemental Content

Physiology and Pharmacology February 2023

Rho Kinase Inhibitor AR-12286 Reverses Steroid-Induced Changes in Intraocular Pressure, Effective Filtration Areas, and Morphology in Mouse Eyes

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Ruiyi Ren; Anne A. Humphrey; Casey Kopczynski; Haiyan Gong
TAGS: eye, filtration, intraocular pressure, kinase inhibitors, mice, ocular hypertension, steroids, language morphology, morphology
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):7. doi: https://doi.org/10.1167/iovs.64.2.7

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Progression of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry

Differences in Outflow Facility Between Angiographically Identified High- Versus Low-Flow Regions of the Conventional Outflow Pathways in Porcine Eyes

Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study

Discriminating Between Compressive Optic Neuropathy With Glaucoma-Like Cupping and Glaucomatous Optic Neuropathy Using OCT and OCTA

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

Morphometric Analysis of Retinal Ganglion Cell Axons in Normal and Glaucomatous Brown Norway Rats Optic Nerves

Choroidal Microvasculature Dropout in the Absence of Parapapillary Atrophy in POAG

Proposed Mechanism of Long-Term Intraocular Pressure Lowering With the Bimatoprost Implant

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

24-Hour Monitoring of Intraocular Pressure Fluctuations Using a Contact Lens Sensor: Diagnostic Performance for Glaucoma Progression

Development of a Novel Valve-Controlled Drug-Elutable Microstent for Microinvasive Glaucoma Surgery: In Vitro and Preclinical In Vivo Studies

ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts

Longitudinal Signal-to-Noise Ratio of Perimetry at Different Severities of Glaucoma

Medical Application of Geometric Deep Learning for the Diagnosis of Glaucoma

Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes

Genetic Associations Between Smoking- and Glaucoma-Related Traits

Beneficial and Detrimental Pressure-Related Effects on Inner Neurons in the Adult Porcine In Vitro Retina

PyVisualFields: A Python Package for Visual Field Analysis

The Effects of Negative Periocular Pressure on Biomechanics of the Optic Nerve Head and Cornea: A Computational Modeling Study

Rho Kinase Inhibitor AR-12286 Reverses Steroid-Induced Changes in Intraocular Pressure, Effective Filtration Areas, and Morphology in Mouse Eyes

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