Glaucoma

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Retinal Cell Biology October 2019

Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

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Paul Ikgan Sia; John P. M. Wood; Glyn Chidlow; Robert Casson
TAGS: creatine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4360-4377. doi: 10.1167/iovs.18-25858

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2019

Optical Coherence Tomography Findings After Childhood Lensectomy

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Moritz C. Daniel; Adam M. Dubis; Becky MacPhee; Patricia Ibanez; Gillian Adams; John Brookes; Maria Papadopoulos; Peng T. Khaw; Maria Theodorou; Annegret H. Dahlmann-Noor
TAGS: child, eye, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4388-4396. doi: 10.1167/iovs.19-26806

Includes: Supplemental Content

Glaucoma October 2019

Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma

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Shouyue Huang; Ping Huang; Huan Yu; Zhongjing Lin; Xiaohong Liu; Xi Shen; Lei Guo; Yisheng Zhong
TAGS: glaucoma, hydrogen sulfide, neuroprotective effect, phosphotransferases, rats, tumor necrosis factors, western blotting, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4346-4359. doi: 10.1167/iovs.19-27507

Articles October 2019

Quantification of Visual Field Variability in Glaucoma: Implications for Visual Field Prediction and Modeling

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Alessandro Rabiolo; Esteban Morales; Abdelmonem A. Afifi; Fei Yu; Kouros Nouri-Mahdavi; Joseph Caprioli
TAGS: glaucoma, visual fields, linear regression
Trans. Vis. Sci. Tech.. 2019; 8(5):25. doi: 10.1167/tvst.8.5.25

Includes: Supplemental Content

Articles October 2019

Relationship of the Macular Ganglion Cell and Inner Plexiform Layers in Healthy and Glaucoma Eyes

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Sasan Moghimi; Nima Fatehi; Andrew H. Nguyen; Pablo Romero; Joseph Caprioli; Kouros Nouri-Mahdavi
TAGS: eye, ganglia, glaucoma
Trans. Vis. Sci. Tech.. 2019; 8(5):27. doi: 10.1167/tvst.8.5.27

Genetics October 2019

Exome Sequencing Reveals a Heterozygous OAS3 Mutation in a Chinese Family With Juvenile-Onset Open-Angle Glaucoma

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Xiaoqiang Xiao; Chukai Huang; Yingjie Cao; Shaowan Chen; Yanxuan Xu; Haoyu Chen; Chipui Pang; Mingzhi Zhang
TAGS: child, chinese (other dialects), chinese people, family, heterozygote, mutation, open-angle glaucoma, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4277-4284. doi: 10.1167/iovs.19-27545

Includes: Supplemental Content

Glaucoma October 2019

Structure-Function Agreement Is Better Than Commonly Thought in Eyes With Early Glaucoma

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Donald C. Hood; Emmanouil Tsamis; Nikhil K. Bommakanti; Devon B. Joiner; Lama L. Al-Aswad; Dana M. Blumberg; George A. Cioffi; Jeffrey M. Liebmann; Carlos G. De Moraes
TAGS: adams-stokes syndrome, angelman syndrome, ankylosing spondylitis, aortic valve stenosis, arsenic, arteriosclerosis, atherosclerosis, atrial fibrillation, eye, glaucoma
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4241-4248. doi: 10.1167/iovs.19-27920

Glaucoma October 2019

Retinal Contrast Gain Control and Temporal Modulation Sensitivity Across the Visual Field in Glaucoma at Photopic and Mesopic Light Conditions

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Catarina A. R. João; Lorenzo Scanferla; Nomdo M. Jansonius
TAGS: glaucoma, perimetry, visual fields, luminance
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4270-4276. doi: 10.1167/iovs.19-27123

Glaucoma October 2019

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

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Massimo A. Fazio; Michael J. A. Girard; Wonyul Lee; Jeffrey S. Morris; Claude F. Burgoyne; J. Crawford Downs
TAGS: eye, intraocular pressure, ocular hypertension, sclera, primates
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4141-4150. doi: 10.1167/iovs.19-27060

Glaucoma October 2019

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

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Kyoung Min Lee; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari; Robert N. Weinreb
TAGS: cornea, corneal hysteresis, cribriform plate, genu varum, open-angle glaucoma, eye, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4171-4177. doi: 10.1167/iovs.19-27087

Includes: Supplemental Content

Articles October 2019

Imaging Distal Aqueous Outflow Pathways in a Spontaneous Model of Congenital Glaucoma

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Kevin C. Snyder; Kazuya Oikawa; Jeremy Williams; Julie A. Kiland; Shaile Gehrke; Leandro B. C. Teixeira; Alex S. Huang; Gillian J. McLellan
TAGS: angiogram, cats, diagnostic imaging, eye, glaucoma, glaucoma, congenital, sclera, spectral-domain optical coherence tomography, body tissue
Trans. Vis. Sci. Tech.. 2019; 8(5):22. doi: 10.1167/tvst.8.5.22

Includes: Supplemental Content

Articles October 2019

Mobility-Related Gaze Training in Individuals With Glaucoma: A Proof-of-Concept Study

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Shaila M. Gunn; Kim Lajoie; Kim T. Zebehazy; Robert A. Strath; David R. Neima; Daniel S. Marigold
TAGS: gait, gaze, glaucoma, mobility, training, proof of concept studies
Trans. Vis. Sci. Tech.. 2019; 8(5):23. doi: 10.1167/tvst.8.5.23

Physiology and Pharmacology October 2019

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

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Evan A. Thackaberry; Yi Zhou; Christina L. Zuch de Zafra; Germaine Fuh; Chingwei V. Lee; Sarah Sanowar; John B. Ridgway; Aija M. Kusi; Cindy Farman; Helen Booler; Daniel Sheinson; Carol A. Rasmussen; Paul E. Miller; Eric Wakshull; Minhong Yan; Vladimir Bantseev
TAGS: antibodies, anti-vascular endothelial growth factor therapy, aqueous humor, eye, glaucoma, intraocular pressure, macaca fascicularis, primates, signal transduction, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4097-4108. doi: 10.1167/iovs.18-26349

Glaucoma September 2019

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

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Maomao Song; Liping Li; Yuan Lei; Xinghuai Sun
TAGS: donors, intraocular pressure, mice, nitric oxide, nitric oxide synthase, nitric oxide synthase inhibitors, cyclic gmp, ng-nitroarginine methyl ester, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4002-4007. doi: 10.1167/iovs.19-27582

Includes: Supplemental Content

Retina September 2019

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

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Min-Woo Lee; Woo-Hyuk Lee; Gi-Seok Park; Hyung-Bin Lim; Jung-Yeul Kim
TAGS: hypertension, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3914-3919. doi: 10.1167/iovs.19-27652

Glaucoma September 2019

Activation of αvβ3 Integrin Alters Fibronectin Fibril Formation in Human Trabecular Meshwork Cells in a ROCK-Independent Manner

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Mark S. Filla; Jennifer A. Faralli; Harini Desikan; Jennifer L. Peotter; Abigail C. Wannow; Donna M. Peters
TAGS: fibril, fibronectins, integrins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3897-3913. doi: 10.1167/iovs.19-27171

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2019

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

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Jessica V. Jasien; Christopher A. Girkin; J. Crawford Downs
TAGS: intraocular pressure, primates, telemetry, wireless technology, ketamine, dexmedetomidine, xylazine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3830-3834. doi: 10.1167/iovs.19-27758

Glaucoma September 2019

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

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Da Zhao; Vickie H. Y. Wong; Christine T. O. Nguyen; Andrew I. Jobling; Erica L. Fletcher; Algis J. Vingrys; Bang V. Bui
TAGS: ganglia, intraocular pressure, pathophysiology, recovery of function, retinal ganglion cells, electroretinography, eye, sutures, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3878-3886. doi: 10.1167/iovs.19-27113

Includes: Supplemental Content

Articles September 2019

Δ 9 -Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

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Pranjal S. Taskar; Akash Patil; Prit Lakhani; Eman Ashour; Waseem Gul; Mahmoud A. ElSohly; Brian Murphy; Soumyajit Majumdar
TAGS: tetrahydrocannabinol, intraocular pressure, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2019; 8(5):15. doi: 10.1167/tvst.8.5.15

Glaucoma September 2019

Fixel-Based Analysis of Visual Pathway White Matter in Primary Open-Angle Glaucoma

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Shereif Haykal; Branislava Ćurčić-Blake; Nomdo M. Jansonius; Frans W. Cornelissen
TAGS: glaucoma, open-angle glaucoma, visual pathways, white matter, otosclerosis, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3803-3812. doi: 10.1167/iovs.19-27447

Includes: Supplemental Content

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Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

Optical Coherence Tomography Findings After Childhood Lensectomy

Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma

Quantification of Visual Field Variability in Glaucoma: Implications for Visual Field Prediction and Modeling

Relationship of the Macular Ganglion Cell and Inner Plexiform Layers in Healthy and Glaucoma Eyes

Exome Sequencing Reveals a Heterozygous OAS3 Mutation in a Chinese Family With Juvenile-Onset Open-Angle Glaucoma

Structure-Function Agreement Is Better Than Commonly Thought in Eyes With Early Glaucoma

Retinal Contrast Gain Control and Temporal Modulation Sensitivity Across the Visual Field in Glaucoma at Photopic and Mesopic Light Conditions

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

Imaging Distal Aqueous Outflow Pathways in a Spontaneous Model of Congenital Glaucoma

Mobility-Related Gaze Training in Individuals With Glaucoma: A Proof-of-Concept Study

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

Activation of αvβ3 Integrin Alters Fibronectin Fibril Formation in Human Trabecular Meshwork Cells in a ROCK-Independent Manner

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

Δ 9 -Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

Fixel-Based Analysis of Visual Pathway White Matter in Primary Open-Angle Glaucoma

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