Immunology and Microbiology

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Immunology and Microbiology September 2018

In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

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Gabrielle Gomart; Julie Denis; Tristan Bourcier; Anne Dory; Ahmed Abou-Bacar; Ermanno Candolfi; Arnaud Sauer
TAGS: acanthamoeba, cysts, ultraviolet a radiation, titanium dioxide, trophozoite
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4567-4571. doi: 10.1167/iovs.18-25003

Includes: Supplemental Content

Article September 2018

Experience-dependent long-term facilitation of skew adaptation

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Selam W. Habtegiorgis; Katharina Rifai; Markus Lappe; Siegfried Wahl
TAGS: facilitation, perceptual aftereffect
Journal of Vision. 2018; 18(9):7. doi: 10.1167/18.9.7

Includes: Supplemental Content

Retinal Cell Biology September 2018

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

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Nilisha Fernando; Yvette Wooff; Riemke Aggio-Bruce; Joshua A. Chu-Tan; Haihan Jiao; Catherine Dietrich; Matt Rutar; Melissa Rooke; Deepthi Menon; Janis T. Eells; Krisztina Valter; Philip G. Board; Jan Provis; Riccardo Natoli
TAGS: oxidative stress, photoreceptors, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4362-4374. doi: 10.1167/iovs.18-24627

Immunology and Microbiology August 2018

Identification and Visualization of a Distinct Microbiome in Ocular Surface Conjunctival Tissue

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Jerome Ozkan; Minas Coroneo; Mark Willcox; Bernd Wemheuer; Torsten Thomas
TAGS: fornix (brain), body tissue, conjunctiva, microorganisms, community, microbiome
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4268-4276. doi: 10.1167/iovs.18-24651

Includes: Supplemental Content

Cornea August 2018

TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway

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Xinhan Cui; Nan Gao; Rao Me; Jianjiang Xu; Fu-Shin X. Yu
TAGS: dendritic cells, keratitis, infection, cornea, mice, bacterial keratitis, thymic stromal lymphopoietin, pseudomonas aeruginosa infection
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4228-4237. doi: 10.1167/iovs.18-24672

Includes: Supplemental Content

Immunology and Microbiology August 2018

Detection of Complement Activators in Immune Attack Eyes After iPS-Derived Retinal Pigment Epithelial Cell Transplantation

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Sunao Sugita; Kenichi Makabe; Shota Fujii; Masayo Takahashi
TAGS: complement system proteins, eye, transplantation, transcriptional activation, idiopathic pneumonia syndrome, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4198-4209. doi: 10.1167/iovs.18-24769

Includes: Supplemental Content

Glaucoma August 2018

Increased Iris Stiffness in Patients With a History of Angle-Closure Glaucoma: An Image-Based Inverse Modeling Analysis

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Anup Dev Pant; Priyanka Gogte; Vanita Pathak-Ray; Syril K. Dorairaj; Rouzbeh Amini
TAGS: medical history, iris, immune reconstitution inflammatory syndrome, angle closure glaucoma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4134-4142. doi: 10.1167/iovs.18-24327

Immunology and Microbiology August 2018

Global Variations and Challenges With Tubercular Uveitis in the Collaborative Ocular Tuberculosis Study

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Rupesh Agrawal; Dinesh Visva Gunasekeran; Dhananjay Raje; Aniruddha Agarwal; Quan Dong Nguyen; Onn Min Kon; Carlos Pavesio; Vishali Gupta; for the Collaborative Ocular Tuberculosis Study Group
TAGS: survival analysis, adrenal corticosteroids, glucocorticoids, india, ophthalmology, signs and symptoms, tuberculosis, tuberculosis, ocular, universities, infection, eye, mineralocorticoids, treatment outcome, tuberculous uveitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4162-4171. doi: 10.1167/iovs.18-24102

Includes: Supplemental Content

Retinal Cell Biology August 2018

MicroRNA-124 Dysregulation is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina

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Joshua A. Chu-Tan; Matt Rutar; Kartik Saxena; Riemke Aggio-Bruce; Rohan W. Essex; Krisztina Valter; Haihan Jiao; Nilisha Fernando; Yvette Wooff; Michele C. Madigan; Jan Provis; Riccardo Natoli
TAGS: monocyte chemoattractant protein-1, photoreceptors, retinal degeneration, retinitis, retina, micrornas
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4094-4105. doi: 10.1167/iovs.18-24623

Includes: Supplemental Content

Biochemistry and Molecular Biology August 2018

Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

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T. J. Hollingsworth; Marko Z. Radic; Sarka Beranova-Giorgianni; Francesco Giorgianni; Yanming Wang; Alessandro Iannaccone
TAGS: western blotting, arginine, peptides, antibodies, mice, retina, citrullination
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3808-3815. doi: 10.1167/iovs.18-24118

Includes: Supplemental Content

Cornea August 2018

Resolvin E1 Inhibits Corneal Allograft Rejection in High-Risk Corneal Transplantation

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Han Wang; Qingqing Zhao; Dan Luo; Yizhou Yin; Ting Li; Min Zhao
TAGS: cytokine, keratoplasty, rejection (psychology), tissue transplants, cornea, transplantation, allografting, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3911-3919. doi: 10.1167/iovs.18-24562

Cornea August 2018

Hemin Promotes Corneal Allograft Survival Through the Suppression of Macrophage Recruitment and Activation

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Ye Dai; Xiaokang Cheng; Jianfeng Yu; Xiaoqing Chen; Yichen Xiao; Fen Tang; Yingqi Li; Shangtao Wan; Wenru Su; Dan Liang
TAGS: hemin, macrophage, cornea, allografting, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3952-3962. doi: 10.1167/iovs.17-23327

Glaucoma August 2018

Resveratrol Delays Retinal Ganglion Cell Loss and Attenuates Gliosis-Related Inflammation From Ischemia-Reperfusion Injury

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Hongdou Luo; Jiejie Zhuang; Piaopiao Hu; Wei Ye; Shanshan Chen; Yulian Pang; Ningfeng Li; Cong Deng; Xu Zhang
TAGS: apoptosis, inflammation, gliosis, reperfusion injury, wounds and injuries, retina, resveratrol, attenuation, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3879-3888. doi: 10.1167/iovs.18-23806

Cornea August 2018

A Novel Murine Model of Radiation Keratopathy

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Deshea L. Harris; Takefumi Yamaguchi; Pedram Hamrah
TAGS: neurons, radiation, cornea, mice, fluorescein stain method, nerve injury, cd45 antigens
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3889-3896. doi: 10.1167/iovs.18-24567

Retinal Cell Biology July 2018

Lactic Acid Upregulates VEGF Expression in Macrophages and Facilitates Choroidal Neovascularization

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Juha Song; Kihwang Lee; Sung Wook Park; Hyewon Chung; Daun Jung; Yi Rang Na; Hailian Quan; Chang Sik Cho; Jeong-Hwan Che; Jeong Hun Kim; Jae-Hak Park; Seung Hyeok Seok
TAGS: vascular endothelial growth factor a, choroidal neovascularization, lasers, macrophage, lactic acid, mice
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3747-3754. doi: 10.1167/iovs.18-23892

Includes: Supplemental Content

Retina July 2018

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment

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Lee Kiang; Bing X. Ross; Jingyu Yao; Sumathi Shanmugam; Chris A. Andrews; Sean Hansen; Cagri G. Besirli; David N. Zacks; Steven F. Abcouwer
TAGS: cytokine, microglia, retinal detachment, rna, messenger, vitreous body, mice, retina, inflammatory response
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3767-3778. doi: 10.1167/iovs.18-24489

Includes: Supplemental Content

Special Issue July 2018

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

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Sayan Ghosh; Peng Shang; Hiroto Terasaki; Nadezda Stepicheva; Stacey Hose; Meysam Yazdankhah; Joseph Weiss; Taiji Sakamoto; Imran A. Bhutto; Shuli Xia; J. Samuel Zigler, Jr; Ram Kannan; Jiang Qian; James T. Handa; Debasish Sinha
TAGS: crystallins, age-related macular degeneration, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD104-AMD113. doi: 10.1167/iovs.18-24132

Includes: Supplemental Content

Retina July 2018

Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage

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Nasir Mat Nor; Cindy X. Guo; Ilva D. Rupenthal; Ying-Shan Chen; Colin R. Green; Monica L. Acosta
TAGS: eye, retina, inflammation, peptides, choroid, connexin 43, photodamage, injections, body tissue, saline solution, fluorescein-5-isothiocyanate, normal saline, nanoparticles, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3682-3693. doi: 10.1167/iovs.17-22829

Special Issue July 2018

A Perspective of AMD Through the Eyes of Immunology

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David A. Copland; Sofia Theodoropoulou; Jian Liu; Andrew D. Dick
TAGS: inflammation, complement system proteins, microglia, body tissue, eye, immunology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD83-AMD92. doi: 10.1167/iovs.18-23893

Cornea July 2018

Tear Film Proteomics Reveal Important Differences Between Patients With and Without Ocular GvHD After Allogeneic Hematopoietic Cell Transplantation

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Nadine Gerber-Hollbach; Kim Plattner; Olivia E. O'Leary; Paul Jenoe; Suzette Moes; Beatrice Drexler; Andreas Schoetzau; Jörg P. Halter; David Goldblum
TAGS: hematopoietic stem cell transplantation, graft-versus-host disease, dry eye syndromes, proteins, proteomics, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3521-3530. doi: 10.1167/iovs.18-24433

Includes: Supplemental Content

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In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

Experience-dependent long-term facilitation of skew adaptation

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

Identification and Visualization of a Distinct Microbiome in Ocular Surface Conjunctival Tissue

TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway

Detection of Complement Activators in Immune Attack Eyes After iPS-Derived Retinal Pigment Epithelial Cell Transplantation

Increased Iris Stiffness in Patients With a History of Angle-Closure Glaucoma: An Image-Based Inverse Modeling Analysis

Global Variations and Challenges With Tubercular Uveitis in the Collaborative Ocular Tuberculosis Study

MicroRNA-124 Dysregulation is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina

Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

Resolvin E1 Inhibits Corneal Allograft Rejection in High-Risk Corneal Transplantation

Hemin Promotes Corneal Allograft Survival Through the Suppression of Macrophage Recruitment and Activation

Resveratrol Delays Retinal Ganglion Cell Loss and Attenuates Gliosis-Related Inflammation From Ischemia-Reperfusion Injury

A Novel Murine Model of Radiation Keratopathy

Lactic Acid Upregulates VEGF Expression in Macrophages and Facilitates Choroidal Neovascularization

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

Sustained Connexin43 Mimetic Peptide Release From Loaded Nanoparticles Reduces Retinal and Choroidal Photodamage

A Perspective of AMD Through the Eyes of Immunology

Tear Film Proteomics Reveal Important Differences Between Patients With and Without Ocular GvHD After Allogeneic Hematopoietic Cell Transplantation

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Immunology and Microbiology

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