Immunology and Microbiology

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Retina March 2019

Retinal Microvascular Abnormalities in Children with Type 1 Diabetes Mellitus Without Visual Impairment or Diabetic Retinopathy

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Tao Li; Yan Jia; Shanshan Wang; Anken Wang; Lu Gao; Chenhao Yang; Haidong Zou
TAGS: diabetes mellitus, diabetes mellitus, type 1, child, visual impairment, diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):990-998. doi: 10.1167/iovs.18-25499

Retinal Cell Biology March 2019

Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

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Rupali Vohra; Blanca I. Aldana; Helle Waagepetersen; Linda H. Bergersen; Miriam Kolko
TAGS: lactates, glutamate, glucose
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):999-1008. doi: 10.1167/iovs.18-25458

Retinal Cell Biology March 2019

Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury

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Wei Liu; Fan Xia; Yonju Ha; Shuang Zhu; Yi Li; Oluwarotimi Folorunso; Aryan Pashaei-Marandi; Pei-Yi Lin; Ronald G. Tilton; Anson P. Pierce; Hua Liu; Wenbo Zhang
TAGS: ischemia, wounds and injuries, eye, mice, proteins, stress, neuroprotective effect, protein overexpression, retina, reperfusion injury, heat-shock proteins 70, reperfusion therapy, retinal ischemia, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):965-977. doi: 10.1167/iovs.18-26216

Includes: Supplemental Content

Immunology and Microbiology March 2019

Impaired Autophagic Degradation of Transforming Growth Factor-β-Induced Protein by Macrophages in Lattice Corneal Dystrophy

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Ji Han; Ming Zhang; Hai-Yan Lin; Feng-Ying Huang; Ying-Ying Lin; Guang-Hong Tan; Zhen-You Zheng
TAGS: autophagy, proteins, catabolism, macrophages, hereditary corneal dystrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):978-989. doi: 10.1167/iovs.18-25838

Includes: Supplemental Content

Glaucoma March 2019

T-Lymphocyte Subset Distribution and Activity in Patients With Glaucoma

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Xiangjun Yang; Qun Zeng; Emre Göktaş; Kalashree Gopal; Lama Al-Aswad; Dana M. Blumberg; George A. Cioffi; Jeffrey M. Liebmann; Gülgün Tezel
TAGS: glaucoma, t-lymphocyte subsets, t-lymphocyte
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):877-888. doi: 10.1167/iovs.18-26129

Cornea February 2019

Longitudinal Changes in Corneal Cell and Nerve Fiber Morphology in Young Patients with Type 1 Diabetes with and without Diabetic Retinopathy: A 2-Year Follow-up Study

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Eszter A. Deák; Eszter Szalai; Noémi Tóth; Rayaz A. Malik; András Berta; Adrienne Csutak
TAGS: diabetes mellitus, type 1, diabetic retinopathy, nerve fibers, cornea, morphology, follow-up studies, language morphology
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):830-837. doi: 10.1167/iovs.18-24516

Glaucoma February 2019

Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation

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Ying Ying Sun; Yong-Feng Yang; Kate E. Keller
TAGS: actins, western blotting, myosin, dimethyl sulfoxide, lentivirus, matrix metalloproteinases, microscopy, confocal, perfusion, phagocytosis, trabecular meshwork, proteins, regulation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):843-851. doi: 10.1167/iovs.18-26055

Includes: Supplemental Content

Retina February 2019

Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases

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Randa S. Eshaq; Norman R. Harris
TAGS: diabetes mellitus, western blotting, cd31 antigens, matrix metalloproteinases, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):748-760. doi: 10.1167/iovs.18-25068

Immunology and Microbiology February 2019

Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes

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Christina N. Como; Andrew N. Bubak; Anna M. Blackmon; Dallas Jones; Niklaus H. Mueller; Richard Davidson; Maria A. Nagel
TAGS: cytokine, human herpesvirus 3, viruses, varicella-zoster virus infections, corneal epithelial cells, keratocytes, cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):704-711. doi: 10.1167/iovs.18-25801

Articles February 2019

Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis

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Hiroyuki Nakashizuka; Hiroyuki Shimada; Takayuki Hattori; Koji Tanaka; Yorihisa Kitagawa; Kei Shinoda
TAGS: electroretinography, endophthalmitis, irrigation, povidone-iodine, vitrectomy, eye, intravitreal injections
Trans. Vis. Sci. Tech.. 2019; 8(1):21. doi: 10.1167/tvst.8.1.21

Article February 2019

Visual communication of how fabrics feel

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Maarten W. A. Wijntjes; Bei Xiao; Robert Volcic
TAGS: judgment, textiles, visual communication
Journal of Vision. 2019; 19(2):4. doi: 10.1167/19.2.4

Retina February 2019

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

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Masaaki Kobayashi; Kazuhiro Tokuda; Yuka Kobayashi; Chiemi Yamashiro; Sho-Hei Uchi; Makoto Hatano; Kazuhiro Kimura
TAGS: fibrosis, cell motility, choroidal neovascularization, gelatin, gelatinase a, immunoblotting, mice, proteins, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):528-537. doi: 10.1167/iovs.18-25678

Immunology and Microbiology January 2019

The Human Ocular Surface Fungal Microbiome

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Sisinthy Shivaji; Rajagopalaboopathi Jayasudha; Gumpili Sai Prashanthi; Sama Kalyana Chakravarthy; Savitri Sharma
TAGS: dna, conjunctiva, eye, fungus, community, microbiome
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):451-459. doi: 10.1167/iovs.18-26076

Includes: Supplemental Content

Retinal Cell Biology January 2019

Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration

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Tina Storm; Thomas Burgoyne; Joshua L. Dunaief; Erik I. Christensen; Clare Futter; Rikke Nielsen
TAGS: ldl-receptor related protein 2, retinal degeneration, mice, ablation, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):322-330. doi: 10.1167/iovs.18-25667

Includes: Multimedia, Supplemental Content

Retina January 2019

Exosomes Derived From Mesenchymal Stem Cells Modulate miR-126 to Ameliorate Hyperglycemia-Induced Retinal Inflammation Via Targeting HMGB1

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Wei Zhang; Yang Wang; Yichun Kong
TAGS: diabetes mellitus, hyperglycemia, inflammation, glucose, retinitis, rats, stem cell, mesenchymal, exosomes, hmgb1 protein
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):294-303. doi: 10.1167/iovs.18-25617

Retinal Cell Biology January 2019

Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ

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Carsten Faber; Helene Bæk Juel; Benjamin Anderschou Holbech Jensen; Jan Pravsgaard Christensen; Jan Ulrik Prause; Allan Randrup Thomsen; Mogens Holst Nissen
TAGS: chemokines, genes, interferons, lymphocytic choriomeningitis virus, virus diseases, infection, choroid, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):192-201. doi: 10.1167/iovs.18-25721

Includes: Supplemental Content

Glaucoma January 2019

Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway

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Yiwen Wang; Deborah Osakue; Enzhi Yang; Yi Zhou; Haiyan Gong; Xiaobo Xia; Yiqin Du
TAGS: stress response, stem cells, endoplasmic reticulum, trabecular meshwork, stress
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):265-273. doi: 10.1167/iovs.18-25477

Includes: Supplemental Content

Cornea January 2019

The Protective Effect of a Topical Mucin Secretagogue on Ocular Surface Damage Induced by Airborne Carbon Black Exposure

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Xiangzhe Li; Boram Kang; Youngsub Eom; Hyung Keun Lee; Hyo Myung Kim; Jong Suk Song
TAGS: western blotting, secretagogues, immunoglobulin e, eye, immunoglobulin g, cytokine, cornea, carbon, prevention, mass or substance concentration per volume, normal saline, mucins, cervical lymph node group
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):255-264. doi: 10.1167/iovs.18-25964

Cornea January 2019

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

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Cameron K. Postnikoff; Andrew D. Pucker; John Laurent; Carrie Huisingh; Gerald McGwin; Jason J. Nichols
TAGS: small cell carcinoma of lung, contact lenses, lens, crystalline, lens (device), leukocytes, eye, sclera, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):226-233. doi: 10.1167/iovs.18-24664

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

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Retinal Microvascular Abnormalities in Children with Type 1 Diabetes Mellitus Without Visual Impairment or Diabetic Retinopathy

Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury

Impaired Autophagic Degradation of Transforming Growth Factor-β-Induced Protein by Macrophages in Lattice Corneal Dystrophy

T-Lymphocyte Subset Distribution and Activity in Patients With Glaucoma

Longitudinal Changes in Corneal Cell and Nerve Fiber Morphology in Young Patients with Type 1 Diabetes with and without Diabetic Retinopathy: A 2-Year Follow-up Study

Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation

Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases

Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes

Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis

Visual communication of how fabrics feel

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

The Human Ocular Surface Fungal Microbiome

Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration

Exosomes Derived From Mesenchymal Stem Cells Modulate miR-126 to Ameliorate Hyperglycemia-Induced Retinal Inflammation Via Targeting HMGB1

Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ

Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway

The Protective Effect of a Topical Mucin Secretagogue on Ocular Surface Damage Induced by Airborne Carbon Black Exposure

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Immunology and Microbiology

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