Multidisciplinary Ophthalmic Imaging

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Multidisciplinary Ophthalmic Imaging April 2025

A Narrowband 635 nm Autofluorescence Peak in Albino Mouse Eyes Found With Multi-Modal Imaging Reveals the Presence of Protoporphyrin IX in the Choroid

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Pengfei Zhang; Suman K. Manna; Mayank Goswami; Robert J. Zawadzki; Edward N. Pugh, Jr
TAGS: albinism, autofluorescence, diagnostic imaging, eye, mice, protoporphyrins, action spectrum, choroid
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):29. https://doi.org/10.1167/iovs.66.4.29

Includes: Supplemental Content

Retina April 2025

Nonperfused Retinal Capillaries—A New Method Developed on OCT and OCTA

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Min Gao; Yukun Guo; Tristan T. Hormel; Jie Wang; Elizabeth White; Dong-Wouk Park; Thomas S. Hwang; Steven T. Bailey; Yali Jia
TAGS: biological markers, blood capillaries, diagnostic imaging, eye, face, noise, angiogram
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):22. https://doi.org/10.1167/iovs.66.4.22

Retina April 2025

Volumetric Measures of Capillary Nonperfusion on Optical Coherence Tomography Angiography Detect Early Ischemia in Diabetes Without Retinopathy

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Janice X. Ong; Hunter J. Lee; Nicole L. Decker; Daniela Castellanos-Canales; Hisashi Fukuyama; Amani A. Fawzi
TAGS: angiogram, blood capillaries, diabetes mellitus, diabetes mellitus, type 2, ischemia, optical coherence tomography, retinal diseases, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):2. https://doi.org/10.1167/iovs.66.4.2

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract April 2025

Poster Session: On the relationship between chromatic sensitivity and vividness of illusory colored signals

Paolo Antonino Grasso; Federico Tommasi; Elisabetta Baldanzi; Alessandro Farini; Massimo Gurioli
TAGS: posters
Journal of Vision. 2025; 25(5):48. https://doi.org/10.1167/jov.25.5.48

Optica Fall Vision Meeting Abstract April 2025

Invited Session III: Machine Learning and AI Approaches to Retinal Diagnostics: Using AI to predict age, sex and disease from retinal OCT images

Anya Hurlbert
TAGS: machine learning
Journal of Vision. 2025; 25(5):30. https://doi.org/10.1167/jov.25.5.30

Retina March 2025

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

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Lukas Goerdt; Andreas Berlin; Liyan Gao; Thomas A. Swain; Sarah S. Kim; Gerald McGwin; Mark E. Clark; Deepayan Kar; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: aging, autofluorescence, eye, lutein, pigment, maps, meridians, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):61. https://doi.org/10.1167/iovs.66.3.61

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging March 2025

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

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Elham Sadeghi; Katherine Du; Oluwaseyi Ajayi; Elli Davis; Nicola Valsecchi; Mohammed Nasar Ibrahim; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: cortical blindness, diabetic retinopathy, eye, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):50. https://doi.org/10.1167/iovs.66.3.50

Retina March 2025

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

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Mark Hedgeland; Sergio Camacho Gonzalez; Dimitrios Stampoulis; Vivian Lee; Kate Powell; Yubin Qiu; Robert Hodge; Greg Bell; Amanda Fago; Rebecca Atkinson-Dell; Nadya Choti; Kirsten Stoner
TAGS: injections, eye, subcutaneous injections
Trans. Vis. Sci. Tech.. 2025; 14(3):20. https://doi.org/10.1167/tvst.14.3.20

Includes: Multimedia, Supplemental Content

Multidisciplinary Ophthalmic Imaging March 2025

Three-Dimensional β-Amyloid Burden Correlation Between the Eye and Brain in Alzheimer's Disease Mice Using Light-Sheet Fluorescence Microscopy

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Hye Joo Son; Seonok Kim; Seog-Young Kim; Jin Hwa Jung; Suk Hyun Lee; Soo-Jong Kim; Chanwoo Kim; Alice Hahn
TAGS: alzheimer's disease, amyloid, brain, eye, mice, microscopy, fluorescence, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):34. https://doi.org/10.1167/iovs.66.3.34

Includes: Multimedia, Supplemental Content

Artificial Intelligence March 2025

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

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Pétra Eid; Abderrahmane Bourredjem; Atif Anwer; Catherine Creuzot-Garcher; Pearse Andrew Keane; Yukun Zhou; Siegfried Wagner; Fabrice Meriaudeau; Louis Arnould
TAGS: biological markers, datasets, fundus photography, retinal imaging, software
Trans. Vis. Sci. Tech.. 2025; 14(3):13. https://doi.org/10.1167/tvst.14.3.13

Includes: Supplemental Content

Review March 2025

Advances in OCT Angiography

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Tristan T. Hormel; David Huang; Yali Jia
TAGS: angiogram, artifacts, diagnostic imaging, deep learning, fluid flow, body tissue
Trans. Vis. Sci. Tech.. 2025; 14(3):6. https://doi.org/10.1167/tvst.14.3.6

Artificial Intelligence March 2025

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

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Bo Zheng; Chen Wang; Maotao Zhang; Shaojun Zhu; Maonian Wu; Tao Wu; Weihua Yang; Lu Chen
TAGS: learning, macular disorders, fundus photography, color, datasets
Trans. Vis. Sci. Tech.. 2025; 14(3):4. https://doi.org/10.1167/tvst.14.3.4

Includes: Supplemental Content

Retina February 2025

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

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Hiroyuki Takahashi; Yunchan Hwang; Jungeun Won; Muhammad Usman Jamil; Antonio Yaghy; Michelle C. Liang; Caroline R. Baumal; Andre J. Witkin; Kyoko Ohno-Matsui; Jay S. Duker; James G. Fujimoto; Nadia K. Waheed
TAGS: diabetic retinal microaneurysm, diabetic retinopathy, fluid flow, macrophage activation syndrome, meconium aspiration syndrome, retinal microaneurysm, vascular flow, blood capillaries
Trans. Vis. Sci. Tech.. 2025; 14(2):27. https://doi.org/10.1167/tvst.14.2.27

Multidisciplinary Ophthalmic Imaging February 2025

Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning–Based baPWV Index From Color Fundus Photographs

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Michiyuki Saito; Mizuho Mitamura; Kanae Fukutsu; Dong Zhenyu; Ryo Ando; Satoru Kase; Satoshi Katsuta; Susumu Ishida
TAGS: attention, color, deep learning, fundus photography, training
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):63. https://doi.org/10.1167/iovs.66.2.63

Includes: Supplemental Content

Glaucoma February 2025

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

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Raymond Fang; Pengpeng Zhang; Daniel Kim; Junghun Kweon; Cheng Sun; Alex S. Huang; Hao F. Zhang
TAGS: optical coherence tomography, pilocarpine, schlemm's canal, visible light, eye, diagnostic imaging, vaccine information sheets, language morphology, morphology
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):47. https://doi.org/10.1167/iovs.66.2.47

Multidisciplinary Ophthalmic Imaging February 2025

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

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Ye He; Pearl Heumann; Melissa Weilin Song; Shin Kadomoto; Srinivas R. Sadda; Ilina D. Pluym; Irena Tsui
TAGS: angiogram, optical coherence tomography, placental insufficiency, pregnancy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):36. https://doi.org/10.1167/iovs.66.2.36

Retina February 2025

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

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Stefan Futterknecht; Philipp Anders; Julia Mai; Sophie Riedl; Ursula Hall; Chrysoula Gabrani; Kristina Pfau; Martin J. Menten; Daniel Rueckert; A. Toby Prevost; Hrvoje Bogunovic; Lars G. Fritsche; Ursula Schmidt-Erfurth; Sobha Sivaprasad; Andrew Lotery; Hendrik P. N. Scholl; Maximilian Pfau
TAGS: drusen, study report, vision, eye, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):6. https://doi.org/10.1167/iovs.66.2.6

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging January 2025

Preferential Sites of Retinal Capillary Occlusion in Sickle Cell Disease

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Oscar Otero-Marquez; Affan Haq; Luis Muncharaz Duran; Jordan Bellis; Sarah McCuskee; Sofia Ahsanuddin; Richard B. Rosen; Jeffrey Glassberg; Toco Y. P. Chui
TAGS: blood capillaries, sickle cell anemia, perfusion
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):57. https://doi.org/10.1167/iovs.66.1.57

Includes: Multimedia, Supplemental Content

Retina January 2025

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

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Christine A. Curcio; Jeffrey D. Messinger; Andreas Berlin; Kenneth R. Sloan; D. Scott McLeod; Malia M. Edwards; Jacques Bijon; K. Bailey Freund
TAGS: age-related macular degeneration, age-related macular degeneration, nonexudative, atrophic condition of skin, atrophy, autofluorescence, drusen, fundus autofluorescence imaging, histology, pathology, clinical, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):49. https://doi.org/10.1167/iovs.66.1.49

Includes: Multimedia, Supplemental Content

Review January 2025

New Directions for Ophthalmic OCT – Handhelds, Surgery, and Robotics

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Julia Foust; Morgan McCloud; Amit Narawane; Robert M. Trout; Xi Chen; Al-Hafeez Dhalla; Jianwei D. Li; Christian Viehland; Mark Draelos; Lejla Vajzovic; Ryan P. McNabb; Anthony N. Kuo; Cynthia A. Toth
TAGS: eye, intraoperative care, robotics, surgical procedures, operative, diagnostic imaging, mobile devices
Trans. Vis. Sci. Tech.. 2025; 14(1):14. https://doi.org/10.1167/tvst.14.1.14

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A Narrowband 635 nm Autofluorescence Peak in Albino Mouse Eyes Found With Multi-Modal Imaging Reveals the Presence of Protoporphyrin IX in the Choroid

Nonperfused Retinal Capillaries—A New Method Developed on OCT and OCTA

Volumetric Measures of Capillary Nonperfusion on Optical Coherence Tomography Angiography Detect Early Ischemia in Diabetes Without Retinopathy

Poster Session: On the relationship between chromatic sensitivity and vividness of illusory colored signals

Invited Session III: Machine Learning and AI Approaches to Retinal Diagnostics: Using AI to predict age, sex and disease from retinal OCT images

Topographic Analysis of Two-Wavelength Autofluorescence Supports Higher Macular Xanthophyll Pigment in AMD Than Aging: ALSTAR2 Baseline

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

Three-Dimensional β-Amyloid Burden Correlation Between the Eye and Brain in Alzheimer's Disease Mice Using Light-Sheet Fluorescence Microscopy

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

Advances in OCT Angiography

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning–Based baPWV Index From Color Fundus Photographs

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

Targeted Microperimetry Grids for Focal Lesions in Intermediate AMD: PINNACLE Study Report 7

Preferential Sites of Retinal Capillary Occlusion in Sickle Cell Disease

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

New Directions for Ophthalmic OCT – Handhelds, Surgery, and Robotics

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