Oncology

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Articles April 2019

Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis

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Armin R. Afshar; Bertil E. Damato; Jay M. Stewart; Lydia B. Zablotska; Ritu Roy; Adam B. Olshen; Nancy M. Joseph; Boris C. Bastian
TAGS: mutation, chromosomes, human, pair 3, gene expression profiling, neoplasm metastasis, genetics, neoplasms, intraocular melanoma, histopathology tests, massively-parallel genome sequencing
Trans. Vis. Sci. Tech.. 2019; 8(2):18. doi: 10.1167/tvst.8.2.18

Review April 2019

Aqueous Humor Markers in Retinoblastoma, a Review

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Benjamin K. Ghiam; Liya Xu; Jesse L. Berry
TAGS: hypertension, child, retinoblastoma, aqueous humor, eye, neoplasms, proteins, survivin, enucleation procedure
Trans. Vis. Sci. Tech.. 2019; 8(2):13. doi: 10.1167/tvst.8.2.13

Includes: Supplemental Content

Cornea January 2019

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

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Cameron K. Postnikoff; Andrew D. Pucker; John Laurent; Carrie Huisingh; Gerald McGwin; Jason J. Nichols
TAGS: small cell carcinoma of lung, contact lenses, lens, crystalline, lens (device), leukocytes, eye, sclera, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):226-233. doi: 10.1167/iovs.18-24664

Perspective January 2019

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

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Justine R. Smith; Jacob Pe'er; Rubens N. Belfort; Fatima Cardoso; Richard D. Carvajal; Carlos Carvalho; Sarah E. Coupland; Laurence Desjardins; Jasmine H. Francis; Brenda L. Gallie; Dan S. Gombos; Hans E. Grossniklaus; Steffen Heegaard; Martine J. Jager; Swathi Kaliki; Bruce R. Ksander; Markus Maeurer; Eduardo Moreno; Jose S. Pulido; Bettina Ryll; Arun D. Singh; Junyang Zhao; António Parreira; David J. Wilson; Joan M. O'Brien
TAGS: cancer, medical oncology, neoplasms, eye cancer, vision research, carcinogenesis, ophthalmology, tumorigenesis, intraocular melanoma
Trans. Vis. Sci. Tech.. 2019; 8(1):9. doi: 10.1167/tvst.8.1.9

Articles December 2018

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

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Kazuyoshi Ohtomo; Reiko Arita; Rika Shirakawa; Tomohiko Usui; Hiroharu Yamashita; Yasuyuki Seto; Satoru Yamagami; for the TS-1 Multicenter Study Group
TAGS: eyelid, meibomian gland, chemotherapy regimen, language morphology, morphology
Trans. Vis. Sci. Tech.. 2018; 7(6):37. doi: 10.1167/tvst.7.6.37

Anatomy and Pathology/Oncology November 2018

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

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Maria Teresa B. C. Bonanomi; Osmar C. Saito; Patricia Picciarelli de Lima; Roberta Chizzotti Bonanomi; Maria Cristina Chammas
TAGS: doppler color flow, vascular flow, doppler echocardiography, retinoblastoma, eye, neoplasms, optic nerve, particle image velocimetry
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5441-5446. doi: 10.1167/iovs.18-24777

Perspective October 2018

Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members

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W. Daniel Stamer; Andrew M. Williams; Stephen Pflugfelder; Sarah E. Coupland
TAGS: research personnel, body tissue, eye, surveys, quality
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4783-4792. doi: 10.1167/iovs.18-25319

Anatomy and Pathology/Oncology September 2018

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

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Zachary K. Goldsmith; William Coppess; Andrew S. Irvine; Kelley Yuan; Samuel R. Barsh; Madison K. Ritter; Matthew W. McEwen; Jacqueline Flores-Otero; Aileen Garcia-Vargas; Magaly Martinez-Ferrer; Rachel C. Brennan; Vanessa M. Morales-Tirado; Matthew W. Wilson
TAGS: signal transduction, cell culture techniques, western blotting, enzyme-linked immunosorbent assay, blood platelets, cell proliferation, flow cytometry, cell lines, cell survival, platelet-derived growth factor, platelet-derived growth factor receptor, retinoblastoma, rna, messenger, seeds, spheroids, cellular, vitreous body, diagnostic imaging, eye, neoplasms, rna, small interfering, nuclear translocation, proto-oncogene proteins c-akt, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4486-4495. doi: 10.1167/iovs.18-24359

Article April 2018

More is better: Relative prevalence of multiple targets affects search accuracy

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Phillip (Xin) Cheng; Anina N. Rich
TAGS: prevalence
Journal of Vision. 2018; 18(4):2. doi: 10.1167/18.4.2

Includes: Supplemental Content

Retina March 2018

Genetic Risk Factors for Radiation Vasculopathy

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Thanos D. Papakostas; Margaux A. Morrison; Anne Marie Lane; Caroline Awh; Margaret M. DeAngelis; Evangelos S. Gragoudas; Ivana K. Kim
TAGS: vascular diseases, single nucleotide polymorphism, radiation, visual impairment, visual acuity, genetic risk
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1547-1553. doi: 10.1167/iovs.17-22791

Editorial March 2018

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2018; 7(2):7. doi: 10.1167/tvst.7.2.7

Anatomy and Pathology/Oncology March 2018

Quantitative Evaluation of Vascular Microcirculation Using Contrast-Enhanced Ultrasound Imaging In Rabbit Models of Choroidal Melanoma

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Min Gao; Jinhua Tang; Kun Liu; Ming Yang; Haiyun Liu
TAGS: melanoma, microcirculation, oryctolagus cuniculus, diagnostic imaging, neoplasms, ultrasonography, contrast-enhanced, malignant melanoma of choroid
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1251-1262. doi: 10.1167/iovs.17-22197

Includes: Supplemental Content

Articles February 2018

Crowd-sourced Ontology for Photoleukocoria: Identifying Common Internet Search Terms for a Potentially Important Pediatric Ophthalmic Sign

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Sandra E. Staffieri; Lisa S. Kearns; Paul G. Sanfilippo; Jamie E. Craig; David A. Mackey; Alex W. Hewitt
TAGS: internet, pediatrics, retinoblastoma, eye, help-seeking behavior
Trans. Vis. Sci. Tech.. 2018; 7(1):18. doi: 10.1167/tvst.7.1.18

Includes: Supplemental Content

Anatomy and Pathology/Oncology February 2018

HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status

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Jinfeng Cao; Niels J. Brouwer; Ekaterina S. Jordanova; Marina Marinkovic; Sjoerd G. van Duinen; Nadine E. de Waard; Bruce R. Ksander; Arend Mulder; Frans H. J. Claas; Mirjam H. M. Heemskerk; Martine J. Jager
TAGS: human leukocyte antigens, cell lines, malignant melanoma of conjunctiva, human leukocyte antigen class i, programmed cell death 1 ligand 1
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1005-1015. doi: 10.1167/iovs.17-23209

Includes: Supplemental Content

Anatomy and Pathology/Oncology February 2018

Leucine-Rich α-2-Glycoprotein-1 (LRG-1) Expression in Retinoblastoma

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Radgonde Amer; Liran Tiosano; Jacob Pe'er
TAGS: vascular endothelial growth factor a, glycoprotein, leucine, retinoblastoma, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):685-692. doi: 10.1167/iovs.17-22785

Anatomy and Pathology/Oncology January 2018

Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma

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Anthony B. Daniels; Michael T. Froehler; Janene M. Pierce; Amy H. Nunnally; M. Wade Calcutt; Thomas M. Bridges; David C. LaNeve; Phillip E. Williams; Kelli L. Boyd; Michelle L. Reyzer; Craig W. Lindsley; Debra L. Friedman; Ann Richmond
TAGS: chemotherapy regimen, melphalan, oryctolagus cuniculus, retinoblastoma, body tissue, vitreous body, eye, pharmacokinetics, toxic effect, treatment effectiveness
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):446-454. doi: 10.1167/iovs.17-22302

Anatomy and Pathology/Oncology January 2018

BRAF , NRAS , and GNAQ Mutations in Conjunctival Melanocytic Nevi

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Jasmine H. Francis; Hans E. Grossniklaus; Larissa A. Habib; Brian Marr; David H. Abramson; Klaus J. Busam
TAGS: mutation, nevus, melanocytic nevus, conjunctiva, nevus of conjunctiva, braf gene
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):117-121. doi: 10.1167/iovs.17-22517

Anatomy and Pathology/Oncology January 2018

ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells

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Salma Kaochar; Jianrong Dong; Marie Torres; Kimal Rajapakshe; Fotis Nikolos; Christel M. Davis; Erik A. Ehli; Cristian Coarfa; Nicholas Mitsiades; Vasiliki Poulaki
TAGS: transcription, genetic, cell cycle, cell lines, gene expression profiling, genes, neoplasm metastasis, transplantation, heterologous, intraocular melanoma, mtor serine-threonine kinases
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):132-143. doi: 10.1167/iovs.17-22454

Includes: Supplemental Content

Anatomy and Pathology/Oncology December 2017

Evaluation of ( fli:GFP ) Casper Zebrafish Embryos as a Model for Human Conjunctival Melanoma

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Kelly Cristine de Sousa Pontes; Arwin Groenewoud; Jinfeng Cao; Livia Maria Silva Ataide; Ewa Snaar-Jagalska; Martine J. Jager
TAGS: cell lines, embryo, zebrafish, malignant melanoma of conjunctiva, vemurafenib
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6065-6071. doi: 10.1167/iovs.17-22023

Lens October 2017

Cataract Avoidance With Proton Therapy in Ocular Melanomas

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Juliette Thariat; Sophie Jacob; Jean-Pierre Caujolle; Celia Maschi; Stéphanie Baillif; Gaelle Angellier; Thibaud Mathis; Laurence Rosier; Adela Carnicer; Joel Hérault; Julia Salleron
TAGS: cataract, eye neoplasms, lens, crystalline, lens (device), protons, avoidance behavior, proton therapy, eye melanomas
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5378-5386. doi: 10.1167/iovs.17-22557

Includes: Supplemental Content

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Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis

Aqueous Humor Markers in Retinoblastoma, a Review

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

More is better: Relative prevalence of multiple targets affects search accuracy

Genetic Risk Factors for Radiation Vasculopathy

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

Quantitative Evaluation of Vascular Microcirculation Using Contrast-Enhanced Ultrasound Imaging In Rabbit Models of Choroidal Melanoma

Crowd-sourced Ontology for Photoleukocoria: Identifying Common Internet Search Terms for a Potentially Important Pediatric Ophthalmic Sign

HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status

Leucine-Rich α-2-Glycoprotein-1 (LRG-1) Expression in Retinoblastoma

Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma

BRAF , NRAS , and GNAQ Mutations in Conjunctival Melanocytic Nevi

ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells

Evaluation of ( fli:GFP ) Casper Zebrafish Embryos as a Model for Human Conjunctival Melanoma

Cataract Avoidance With Proton Therapy in Ocular Melanomas

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