Pharmacology

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Retina February 2019

Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina

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Mark K. Webster; Betty J. Barnett; Megan L. Stanchfield; Joshua R. Paris; Sarah E. Webster; Cynthia A. Cooley-Themm; Edward M. Levine; Deborah C. Otteson; Cindy L. Linn
TAGS: cell cycle, adult, bromodeoxyuridine, mammals, neuroglia, neurons, mice, retina, agonists, eyedrops, reentry, neural development, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):570-579. doi: 10.1167/iovs.18-25722

Articles January 2019

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

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Susan S. Lee; Alexandra Almazan; Sherri Decker; Yan Zhong; Alazar N. Ghebremeskel; Patrick Hughes; Michael R. Robinson; James A. Burke; Robert N. Weinreb
TAGS: intraocular pressure, pharmacokinetics, bimatoprost
Trans. Vis. Sci. Tech.. 2019; 8(1):15. doi: 10.1167/tvst.8.1.15

Articles January 2019

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

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Wenqiang Liu; Marta Arias Borrell; David C. Venerus; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: hydrogel, hydrogels, edema, temperature, ranibizumab, body temperature, drug delivery systems, microspheres
Trans. Vis. Sci. Tech.. 2019; 8(1):12. doi: 10.1167/tvst.8.1.12

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

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Kazuyoshi Ohtomo; Reiko Arita; Rika Shirakawa; Tomohiko Usui; Hiroharu Yamashita; Yasuyuki Seto; Satoru Yamagami; for the TS-1 Multicenter Study Group
TAGS: eyelid, meibomian gland, chemotherapy regimen, language morphology, morphology
Trans. Vis. Sci. Tech.. 2018; 7(6):37. doi: 10.1167/tvst.7.6.37

Article December 2018

Adaptation to dynamic faces produces face identity aftereffects

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Samantha Petrovski; Gillian Rhodes; Linda Jeffery
TAGS: face, perceptual aftereffect
Journal of Vision. 2018; 18(13):13. doi: 10.1167/18.13.13

Biochemistry and Molecular Biology December 2018

The Effect of Prostaglandin Analogue Bimatoprost on Thyroid-Associated Orbitopathy

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Catherine J. Choi; Wensi Tao; Ravi Doddapaneni; Zenith Acosta-Torres; Nathan W. Blessing; Bradford W. Lee; Daniel Pelaez; Sara T. Wester
TAGS: prostaglandins, synthetic, bimatoprost
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5912-5923. doi: 10.1167/iovs.18-25134

Cornea December 2018

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

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Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: hyperglycemia, diabetes mellitus, type 1, body weight, alloxan, neurons, streptozocin, sural nerve, cornea, mice, nerve lesions
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5868-5875. doi: 10.1167/iovs.18-25693

Retina December 2018

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

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Gerard A. Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; Lisa M. Hernandez; James Burke; Keith A. Luhrs; Thomas C. Hohman
TAGS: angiogenesis, vascular endothelial growth factor a, oryctolagus cuniculus, bevacizumab, ranibizumab, affinity, aflibercept, anti-vascular endothelial growth factor therapy, vascular permeability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5836-5846. doi: 10.1167/iovs.18-25307

Articles December 2018

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

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Dan Ramon; Jonathan Shahar; Amir Massarweh; Irit Man; Ido Perlman; Anat Loewenstein
TAGS: albinism, glial fibrillary acidic protein, eye, retina, retinal toxicity, intravitreal injections, ziv-aflibercept, electroretinography, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2018; 7(6):23. doi: 10.1167/tvst.7.6.23

Articles November 2018

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

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Kara M. Cavuoto; Santanu Banerjee; Darlene Miller; Anat Galor
TAGS: child, infant, eye, microbiome
Trans. Vis. Sci. Tech.. 2018; 7(6):16. doi: 10.1167/tvst.7.6.16

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Model to Study Central Serous Chorioretinopathy

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Joost Brinks; Elon H. C. van Dijk; Mahmoud Habeeb; Aikaterini Nikolaou; Roula Tsonaka; Hendrika A. B. Peters; Hetty C. M. Sips; Arjanneke F. van de Merbel; Eiko K. de Jong; Robbert G. E. Notenboom; Szymon M. Kielbasa; Silvère M. van der Maarel; Paul H. A. Quax; Onno C. Meijer; Camiel J. F. Boon
TAGS: hydrocortisone, endothelial cells, adrenal corticosteroids, glucocorticoids, patient isolation, mineralocorticoids, agonists, antagonists, central serous chorioretinopathy, chronic exertional compartment syndrome
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5682-5692. doi: 10.1167/iovs.18-25054

Includes: Supplemental Content

Special Issue November 2018

Functional Visual Acuity

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Minako Kaido
TAGS: glaucoma, cataract, vision, visual acuity, quality, system of measurement
Invest. Ophthalmol. Vis. Sci.. 2018; 59(14):DES29-DES35. doi: 10.1167/iovs.17-23721

Special Issue November 2018

Autologous Serum and Serum Components

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Akihiro Higuchi
TAGS: dry eye syndromes, eyedrops
Invest. Ophthalmol. Vis. Sci.. 2018; 59(14):DES121-DES129. doi: 10.1167/iovs.17-23760

Retina November 2018

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

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Shueh Wen Lim; Esther Bandala-Sanchez; Maria Kolic; Sophie L. Rogers; Annie K. McAuley; Lyndell L. Lim; Sanjeewa S. Wickremasinghe
TAGS: cytokine, vascular endothelial growth factor a, inflammation, eye, macular edema, diabetic, ranibizumab
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5382-5390. doi: 10.1167/iovs.17-23325

Includes: Supplemental Content

Retina November 2018

Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization

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Steven Hyun Seung Lee; Hee Jong Kim; Oh Kyu Shin; Jun-Sub Choi; Jin Kim; Young-Hwa Cho; Joohun Ha; Tae Kwann Park; Joo Yong Lee; Keerang Park; Heuiran Lee
TAGS: vascular endothelial growth factor a, vegfr-1, choroidal neovascularization, mice, bevacizumab, intravitreal injections, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5398-5407. doi: 10.1167/iovs.18-24926

Includes: Supplemental Content

Cornea October 2018

Plasminogen-Dependent Collagenolytic Properties of Staphylococcus aureus in Collagen Gel Cultures of Human Corneal Fibroblasts

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Koji Sugioka; Aya Kodama-Takahshi; Tomoko Sato; Kiyotaka Okada; Junko Murakami; Ah-Mee Park; Hiroshi Mishima; Yoshikazu Shimomura; Shunji Kusaka; Teruo Nishida
TAGS: urokinase, fibroblasts, collagen, gel, plasminogen, cornea, catabolism
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5098-5107. doi: 10.1167/iovs.18-24925

Retina October 2018

How to Ward Off Retinal Toxicity of Perfluorooctane and Other Perfluorocarbon Liquids?

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Dirk-Henning Menz; Nicolas Feltgen; Helge Menz; Bernd-Kristof Müller; Thorsten Lechner; Joachim Dresp; Hans Hoerauf
TAGS: patent foramen ovale, fluorides, fluorocarbons, patients' rooms, safety, cytotoxicity, retinal toxicity, liquids, perfluorooctane
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4841-4846. doi: 10.1167/iovs.18-24698

Immunology and Microbiology September 2018

In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

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Gabrielle Gomart; Julie Denis; Tristan Bourcier; Anne Dory; Ahmed Abou-Bacar; Ermanno Candolfi; Arnaud Sauer
TAGS: acanthamoeba, cysts, ultraviolet a radiation, titanium dioxide, trophozoite
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4567-4571. doi: 10.1167/iovs.18-25003

Includes: Supplemental Content

Biochemistry and Molecular Biology September 2018

Inhibitory Effect of Idelalisib, a Selective Phosphatidylinositol 3-Kinase δ Inhibitor, on Adipogenesis in an In Vitro Model of Graves' Orbitopathy

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JaeSang Ko; Ji-Young Kim; Eun Jig Lee; Jin Sook Yoon
TAGS: fibroblasts, 1-phosphatidylinositol 3-kinase, idelalisib
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4477-4485. doi: 10.1167/iovs.18-24509

Includes: Supplemental Content

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Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

Adaptation to dynamic faces produces face identity aftereffects

The Effect of Prostaglandin Analogue Bimatoprost on Thyroid-Associated Orbitopathy

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

The Effect of Corticosteroids on Human Choroidal Endothelial Cells: A Model to Study Central Serous Chorioretinopathy

Functional Visual Acuity

Autologous Serum and Serum Components

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization

Plasminogen-Dependent Collagenolytic Properties of Staphylococcus aureus in Collagen Gel Cultures of Human Corneal Fibroblasts

How to Ward Off Retinal Toxicity of Perfluorooctane and Other Perfluorocarbon Liquids?

In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

Inhibitory Effect of Idelalisib, a Selective Phosphatidylinositol 3-Kinase δ Inhibitor, on Adipogenesis in an In Vitro Model of Graves' Orbitopathy

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