Pharmacology

Showing 1 – 20 of 1843

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Visual Neuroscience April 2019

ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice

PDF

Run-Ze Cui; Lu Wang; Sheng-Nan Qiao; Yong-Chen Wang; Xin Wang; Fei Yuan; Shi-Jun Weng; Xiong-Li Yang; Yong-Mei Zhong
TAGS: diabetes mellitus, streptozocin, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1644-1656. doi: 10.1167/iovs.18-26359

Retina April 2019

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

PDF

Bruce A. Berkowitz; Robert H. Podolsky; Karen M. Lins-Childers; Yichao Li; Haohua Qian
TAGS: oxidative stress, diltiazem, mice, apraxia of speech, aneurysms-osteoarthritis syndrome, saline solutions
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1566-1570. doi: 10.1167/iovs.18-26164

Glaucoma April 2019

Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation

PDF

Yan Hu; Arturo O. Barron; Sofya Gindina; Sandeep Kumar; Shravan Chintala; Ashima Nayyar; John Danias
TAGS: alteplase, urokinase, gelatinase b, platelet count measurement, mice, regulation, fibrinolysis pathway
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1571-1580. doi: 10.1167/iovs.18-25698

Clinical and Epidemiologic Research April 2019

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

PDF

Emily E. Brown; Jacob D. Ball; Zhaoyi Chen; Gibran S. Khurshid; Mattia Prosperi; John D. Ash
TAGS: metformin, age-related macular degeneration, antidiabetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1470-1477. doi: 10.1167/iovs.18-26422

Physiology and Pharmacology April 2019

PARP Inhibitor Protects Against Chronic Hypoxia/Reoxygenation-Induced Retinal Injury by Regulation of MAPKs, HIF1α, Nrf2, and NFκB

PDF

Krisztina Kovacs; Alexandra Vaczy; Katalin Fekete; Petra Kovari; Tamas Atlasz; Dora Reglodi; Robert Gabriel; Ferenc Gallyas; Balazs Sumegi
TAGS: hypoxia, retina, retinal injuries, poly(adp-ribose) polymerase inhibitors, olaparib, hypoxia chronic
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1478-1490. doi: 10.1167/iovs.18-25936

Cornea March 2019

Rapamycin Rescues Endoplasmic Reticulum Stress–Induced Dry Eye Syndrome in Mice

PDF

Bum-Joo Cho; Jin Sun Hwang; Young Joo Shin; Jeong Won Kim; Tae-Young Chung; Joon Young Hyon
TAGS: inflammation, rapamycin, dry eye syndromes, endoplasmic reticulum, mice, stress
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1254-1264. doi: 10.1167/iovs.18-25583

Biochemistry and Molecular Biology March 2019

Bromfenac Inhibits TGF-β1–Induced Fibrotic Effects in Human Pterygium and Conjunctival Fibroblasts

PDF

Kailin Chen; Kairan Lai; Xiaobo Zhang; Zhenwei Qin; Qiuli Fu; Chenqi Luo; Xiuming Jin; Jianghua Hu; Siyu Liu; Ke Yao
TAGS: fibroblasts, conjunctiva, pterygium, proto-oncogene proteins c-akt, bromfenac, hpfs trial
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1156-1164. doi: 10.1167/iovs.18-24743

Includes: Supplemental Content

Cornea March 2019

A New Ophthalmic Pharmaceutical Formulation, Topical Sulglycotide, Enhances the Ocular Mucin Secretion in Desiccation Stress-Mediated Dry Eye Disease

PDF

Hyesook Lee; Sangwon Jeon; Chae Eun Kim; Young-Joon Park; Jaewook Yang
TAGS: dry eye syndromes, cornea, eye, stress, mucins, dosage forms, desiccation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1076-1087. doi: 10.1167/iovs.18-24935

Retina February 2019

Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses

PDF

Jurgen Sergeys; Isabelle Etienne; Inge Van Hove; Evy Lefevere; Ingeborg Stalmans; Jean H. M. Feyen; Lieve Moons; Tine Van Bergen
TAGS: diabetes mellitus, streptozocin, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):807-822. doi: 10.1167/iovs.18-25372

Includes: Supplemental Content

Retina February 2019

Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina

PDF

Mark K. Webster; Betty J. Barnett; Megan L. Stanchfield; Joshua R. Paris; Sarah E. Webster; Cynthia A. Cooley-Themm; Edward M. Levine; Deborah C. Otteson; Cindy L. Linn
TAGS: cell cycle, adult, bromodeoxyuridine, mammals, neuroglia, neurons, mice, retina, agonists, eyedrops, reentry, neural development, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):570-579. doi: 10.1167/iovs.18-25722

Articles January 2019

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

PDF

Susan S. Lee; Alexandra Almazan; Sherri Decker; Yan Zhong; Alazar N. Ghebremeskel; Patrick Hughes; Michael R. Robinson; James A. Burke; Robert N. Weinreb
TAGS: intraocular pressure, pharmacokinetics, bimatoprost
Trans. Vis. Sci. Tech.. 2019; 8(1):15. doi: 10.1167/tvst.8.1.15

Articles January 2019

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

PDF

Wenqiang Liu; Marta Arias Borrell; David C. Venerus; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: hydrogel, hydrogels, edema, temperature, ranibizumab, body temperature, drug delivery systems, microspheres
Trans. Vis. Sci. Tech.. 2019; 8(1):12. doi: 10.1167/tvst.8.1.12

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

PDF

Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

PDF

Kazuyoshi Ohtomo; Reiko Arita; Rika Shirakawa; Tomohiko Usui; Hiroharu Yamashita; Yasuyuki Seto; Satoru Yamagami; for the TS-1 Multicenter Study Group
TAGS: eyelid, meibomian gland, chemotherapy regimen, language morphology, morphology
Trans. Vis. Sci. Tech.. 2018; 7(6):37. doi: 10.1167/tvst.7.6.37

Article December 2018

Adaptation to dynamic faces produces face identity aftereffects

PDF

Samantha Petrovski; Gillian Rhodes; Linda Jeffery
TAGS: face, perceptual aftereffect
Journal of Vision. 2018; 18(13):13. doi: 10.1167/18.13.13

Biochemistry and Molecular Biology December 2018

The Effect of Prostaglandin Analogue Bimatoprost on Thyroid-Associated Orbitopathy

PDF

Catherine J. Choi; Wensi Tao; Ravi Doddapaneni; Zenith Acosta-Torres; Nathan W. Blessing; Bradford W. Lee; Daniel Pelaez; Sara T. Wester
TAGS: prostaglandins, synthetic, bimatoprost
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5912-5923. doi: 10.1167/iovs.18-25134

Cornea December 2018

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

PDF

Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: hyperglycemia, diabetes mellitus, type 1, body weight, alloxan, neurons, streptozocin, sural nerve, cornea, mice, nerve lesions
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5868-5875. doi: 10.1167/iovs.18-25693

Retina December 2018

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

PDF

Gerard A. Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; Lisa M. Hernandez; James Burke; Keith A. Luhrs; Thomas C. Hohman
TAGS: angiogenesis, vascular endothelial growth factor a, oryctolagus cuniculus, bevacizumab, ranibizumab, affinity, aflibercept, anti-vascular endothelial growth factor therapy, vascular permeability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5836-5846. doi: 10.1167/iovs.18-25307

Articles December 2018

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

PDF

Dan Ramon; Jonathan Shahar; Amir Massarweh; Irit Man; Ido Perlman; Anat Loewenstein
TAGS: albinism, glial fibrillary acidic protein, eye, retina, retinal toxicity, intravitreal injections, ziv-aflibercept, electroretinography, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2018; 7(6):23. doi: 10.1167/tvst.7.6.23

Articles November 2018

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

PDF

Kara M. Cavuoto; Santanu Banerjee; Darlene Miller; Anat Galor
TAGS: child, infant, eye, microbiome
Trans. Vis. Sci. Tech.. 2018; 7(6):16. doi: 10.1167/tvst.7.6.16

Includes: Supplemental Content

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation

The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration

PARP Inhibitor Protects Against Chronic Hypoxia/Reoxygenation-Induced Retinal Injury by Regulation of MAPKs, HIF1α, Nrf2, and NFκB

Rapamycin Rescues Endoplasmic Reticulum Stress–Induced Dry Eye Syndrome in Mice

Bromfenac Inhibits TGF-β1–Induced Fibrotic Effects in Human Pterygium and Conjunctival Fibroblasts

A New Ophthalmic Pharmaceutical Formulation, Topical Sulglycotide, Enhances the Ocular Mucin Secretion in Desiccation Stress-Mediated Dry Eye Disease

Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses

Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

Adaptation to dynamic faces produces face identity aftereffects

The Effect of Prostaglandin Analogue Bimatoprost on Thyroid-Associated Orbitopathy

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

This feature is available to authenticated users only.

Pharmacology

To View More...

You must be signed into an individual account to use this feature.