Pharmacology

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Cornea & External Disease September 2023

Effects of In Vitro Combination of Nitric Oxide Donors and Hypochlorite on Acanthamoeba castellanii Viability

PDF

Joo-Hee Park; Choul Yong Park
TAGS: acanthamoeba, donors, nitric oxide, nitric oxide donors, toxic effect, acanthamoeba castellanii, mass or substance concentration per volume, single nucleotide polymorphism
Trans. Vis. Sci. Tech.. 2023; 12(9):23. https://doi.org/10.1167/tvst.12.9.23

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2023

The Association of Antibiotic Use and the Odds of a New-Onset ICD Code Diagnosis of Age-Related Macular Degeneration: A Large National Case-Control Study

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John Moir; Max Hyman; Jessie Wang; Andrea Flores; Dimitra Skondra
TAGS: antibiotics, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):14. https://doi.org/10.1167/iovs.64.12.14

Includes: Supplemental Content

Cornea & External Disease September 2023

Ocular Pharmacology and Toxicology of TRPV1 Antagonist SAF312 (Libvatrep)

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Muneto Mogi; Anisha E. Mendonza; James Chastain; John T. Demirs; Quintus G. Medley; Qin Zhang; Julien P. N. Papillon; Junzheng Yang; Yan Gao; YongYao Xu; Kalliopi Stasi
TAGS: cornea, ocular surfaces, pain, pharmacology, toxicology, transient receptor potential v1 antagonists, trpv1 receptor, wound healing, oryctolagus cuniculus, keratectomy
Trans. Vis. Sci. Tech.. 2023; 12(9):5. https://doi.org/10.1167/tvst.12.9.5

Includes: Supplemental Content

Retina September 2023

Pharmacokinetics of Orbital Topotecan After Ophthalmic Artery Chemosurgery and Intravenous Infusion in the Swine Model

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Flavio Requejo; Javier Opezzo; Alan Vater; Marcelo Asprea; Eduardo Lagomarsino; Claudia Sampor; Adriana Fandiño; Guillermo Chantada; Jasmine H. Francis; David H. Abramson; Paula Schaiquevich
TAGS: intravenous infusion procedures, ophthalmic artery, retinoblastoma, suidae, topotecan, pharmacokinetics, orbit
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):3. https://doi.org/10.1167/iovs.64.12.3

Clinical Trials September 2023

Impact of Prophylactic Ranibizumab to Prevent Neovascular Age-Related Macular Degeneration on Eyes With Intermediate Age-Related Macular Degeneration

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Clement K. Chan; Wesley T. Beaulieu; Brandon J. Lujan; Maziar Lalezary; Daniella Lent-Schochet; Therlinder Lo; Glenn Yiu
TAGS: age-related macular degeneration, exudative age-related macular degeneration, eye, ranibizumab, drusen, injections, volume, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2023; 12(9):1. https://doi.org/10.1167/tvst.12.9.1

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract September 2023

Contributed Session I: Foveal RGCs develop abnormal calcium clearance weeks after photoreceptor ablation

Zhengyang Xu; Karteek Kunala; Peter Murphy; Edith Koo; Teresa Puthussery; Juliette E. McGregor
TAGS: ablation, calcium, drug clearance, photoreceptors
Journal of Vision. 2023; 23(11):11. https://doi.org/10.1167/jov.23.11.11

Retina August 2023

Active Transport and Ocular Distribution of Intravitreally Injected Liposomes

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Anne Zebitz Eriksen; Fredrik Melander; Grace De Malona Eriksen; Paul Joseph Kempen; Andreas Kjaer; Thomas Lars Andresen; Andrew James Urquhart
TAGS: liposomes, active biological transport
Trans. Vis. Sci. Tech.. 2023; 12(8):20. https://doi.org/10.1167/tvst.12.8.20

Retina August 2023

Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case–Control Study

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Gabriel T. Kaufmann; Max J. Hyman; Reem Gonnah; Seenu Hariprasad; Dimitra Skondra
TAGS: age-related macular degeneration, diabetes mellitus, diabetes mellitus, type 2, metformin, drug usage
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):22. https://doi.org/10.1167/iovs.64.11.22

Includes: Supplemental Content

Article August 2023

The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model

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Howard S. Hock; Gregor Schöner
TAGS: excitation, hysteresis, memory, stabilization, tarsus, animal
Journal of Vision. 2023; 23(8):12. https://doi.org/10.1167/jov.23.8.12

Biochemistry and Molecular Biology August 2023

Intrinsic Disorder in the Human Tear Proteome

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David J. Taylor Gonzalez; Mak Djulbegovic; Michael Antonietti; Matthew Cordova; Guy W. Dayhoff, II; Robby Mattes; Anat Galor; Vladimir N. Uversky; Carol L. Karp
TAGS: proteins, proteome
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):14. https://doi.org/10.1167/iovs.64.11.14

Includes: Supplemental Content

Clinical Trials August 2023

Effects of Carboxymethylcellulose Artificial Tears on Ocular Surface Microbiome Diversity and Composition, A Randomized Controlled Trial

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Yujia Zhou; Gurjit S. Sidhu; Joan A. Whitlock; Bishoy Abdelmalik; Zachary Mayer; Youlei Li; Gary P. Wang; Walter A. Steigleman
TAGS: antithymoglobulin, arterial tortuosity syndrome, carboxymethylcellulose, eye, microbiome, ocular lubricants, ocular surfaces, periodic paralysis, potassium-sensitive cardiodysrhythmic type, randomized controlled trial, signs and symptoms
Trans. Vis. Sci. Tech.. 2023; 12(8):5. https://doi.org/10.1167/tvst.12.8.5

Cornea & External Disease June 2023

Evaluating Viscosity and Tear Breakup Time of Contemporary Commercial Ocular Lubricants on an In Vitro Eye Model

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Chau-Minh Phan; Mitchell Ross; Karim Fahmy; Blair McEwen; Ilan Hofmann; Vivian W. Y. Chan; Connor Clark-Baba; Lyndon Jones
TAGS: eye, ocular lubricants, viscosity, medroxyprogesterone acetate, microscopic polyarteritis nodosa, mycophenolic acid
Trans. Vis. Sci. Tech.. 2023; 12(6):29. https://doi.org/10.1167/tvst.12.6.29

Retina June 2023

Randomized Trial of Treat-and-Extend Intravitreal Aflibercept for Radiation Retinopathy: 1-Year Outcomes

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Stephanie Trejo Corona; Cecilia Villanueva Boone; Amna M. Ali; Chelsey Moore; Alexandra Brown; Jose Munoz; Thomas Aaberg, Jr.; Amy C. Schefler; on behalf of the ARRT Study Group
TAGS: aflibercept, cohort studies, radiation retinopathy, randomized controlled trial, injections, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):35. https://doi.org/10.1167/iovs.64.7.35

Includes: Supplemental Content

Perspective June 2023

Immune Checkpoint Inhibitor Therapy for Orbital and Ocular Adnexal Squamous Cell Carcinomas: International Society of Ocular Oncology President's Lecture, 2022

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Bita Esmaeli
TAGS: cancer, immune checkpoint inhibitors, immunotherapy, squamous cell carcinoma, medical oncology, societies
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):29. https://doi.org/10.1167/iovs.64.7.29

Retina June 2023

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates

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Ygal Rotenstreich; Ifat Sher; Matthew Lawrence; Miriam Mangelus; Avner Ingerman; Yoreh Barak
TAGS: cercopithecidae, diagnostic imaging, drug delivery systems, eye, injections, primates, retina, subcutaneous injections, intraocular pressure, sclera
Trans. Vis. Sci. Tech.. 2023; 12(6):3. https://doi.org/10.1167/tvst.12.6.3

Retina June 2023

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

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Ke Xiao; Xiao-Hong Ma; Zheng Zhong; Yin Zhao; Xu-Hui Chen; Xu-Fang Sun
TAGS: diabetes mellitus, ganglia, resveratrol, retinal ganglion cells, tissue degeneration, western blotting, nuclear translocation, apoptosis, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):2. https://doi.org/10.1167/iovs.64.7.2

Includes: Supplemental Content

Letters to the Editor May 2023

Letter to the Editor: Characterization of Choriocapillaris and Choroidal Abnormalities in Alport Syndrome

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Damir Bosnar; Mira Knežić Zagorec; Mladen Bušić; Valentina Cigić; Nikola Zagorec; Tamara Nikuševa Martić; Danica Galešić Ljubanović
TAGS: hereditary nephritis
Trans. Vis. Sci. Tech.. 2023; 12(5):25. https://doi.org/10.1167/tvst.12.5.25

Retina May 2023

Aflibercept Suppression of Angiopoietin-2 in a Rabbit Retinal Vascular Hyperpermeability Model

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Claudia Lange; Reimo Tetzner; Tobias Strunz; Kay D. Rittenhouse
TAGS: aflibercept, angiopoietins, anti-vascular endothelial growth factor therapy, oryctolagus cuniculus, proteins, retina, rna, messenger, vascular endothelial growth factor a, body tissue, retinal diseases
Trans. Vis. Sci. Tech.. 2023; 12(5):17. https://doi.org/10.1167/tvst.12.5.17

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2023

Müller's Muscle as a Sensory Proprioceptive Organ: Histological and Histochemical Analysis

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Daphna Landau-Prat; Chen Mayer; Nir Gomel; Mattan Arazi; Ofira Zloto; Amir Dori; Guy J. Ben Simon
TAGS: methylene blue, muscle, eyelid, axon, myelin sheath, immunohistochemistry, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):18. https://doi.org/10.1167/iovs.64.5.18

Retinal Cell Biology May 2023

Differential Eye Expression of Xenopus Acyltransferase Gnpat and Its Biochemical Characterization Shed Light on Lipid-Associated Ocular Pathologies

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Gabriel E. Bertolesi; Maxwell F. J. Chilije; Victoria Li; Chase C. Thompson; Arturo López-Villalobos; Carrie L. Hehr; Karen Atkinson-Leadbeater; Vanina Zaremberg; Sarah McFarlane
TAGS: acyltransferase, eye, lipids, proteins, xenopus, embryo, yeasts, enzymes, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):17. https://doi.org/10.1167/iovs.64.5.17

Includes: Supplemental Content

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Effects of In Vitro Combination of Nitric Oxide Donors and Hypochlorite on Acanthamoeba castellanii Viability

The Association of Antibiotic Use and the Odds of a New-Onset ICD Code Diagnosis of Age-Related Macular Degeneration: A Large National Case-Control Study

Ocular Pharmacology and Toxicology of TRPV1 Antagonist SAF312 (Libvatrep)

Pharmacokinetics of Orbital Topotecan After Ophthalmic Artery Chemosurgery and Intravenous Infusion in the Swine Model

Impact of Prophylactic Ranibizumab to Prevent Neovascular Age-Related Macular Degeneration on Eyes With Intermediate Age-Related Macular Degeneration

Contributed Session I: Foveal RGCs develop abnormal calcium clearance weeks after photoreceptor ablation

Active Transport and Ocular Distribution of Intravitreally Injected Liposomes

Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case–Control Study

The stabilization of visibility for sequentially presented, low-contrast objects: Experiments and neural field model

Intrinsic Disorder in the Human Tear Proteome

Effects of Carboxymethylcellulose Artificial Tears on Ocular Surface Microbiome Diversity and Composition, A Randomized Controlled Trial

Evaluating Viscosity and Tear Breakup Time of Contemporary Commercial Ocular Lubricants on an In Vitro Eye Model

Randomized Trial of Treat-and-Extend Intravitreal Aflibercept for Radiation Retinopathy: 1-Year Outcomes

Immune Checkpoint Inhibitor Therapy for Orbital and Ocular Adnexal Squamous Cell Carcinomas: International Society of Ocular Oncology President's Lecture, 2022

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates

Low-Dose Trans -Resveratrol Ameliorates Diabetes-Induced Retinal Ganglion Cell Degeneration via TyrRS/c-Jun Pathway

Letter to the Editor: Characterization of Choriocapillaris and Choroidal Abnormalities in Alport Syndrome

Aflibercept Suppression of Angiopoietin-2 in a Rabbit Retinal Vascular Hyperpermeability Model

Müller's Muscle as a Sensory Proprioceptive Organ: Histological and Histochemical Analysis

Differential Eye Expression of Xenopus Acyltransferase Gnpat and Its Biochemical Characterization Shed Light on Lipid-Associated Ocular Pathologies

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