Retina

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Multidisciplinary Ophthalmic Imaging September 2018

Cone Photoreceptor Cell Segmentation and Diameter Measurement on Adaptive Optics Images Using Circularly Constrained Active Contour Model

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Jianfei Liu; HaeWon Jung; Alfredo Dubra; Johnny Tam
TAGS: retinal cone, diameter
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4639-4652. doi: 10.1167/iovs.18-24734

Includes: Supplemental Content

Special Issue September 2018

Retest Reliability of Mesopic and Dark-Adapted Microperimetry in Patients With Intermediate Age-Related Macular Degeneration and Age-Matched Controls

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Susanne G. Welker; Maximilian Pfau; Manuel Heinemann; Steffen Schmitz-Valckenberg; Frank G. Holz; Robert P. Finger
TAGS: age-related macular degeneration, reliability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD152-AMD159. doi: 10.1167/iovs.18-23878

Genetics September 2018

IFT52 as a Novel Candidate for Ciliopathies Involving Retinal Degeneration

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Xue Chen; Xiaoguang Wang; Chao Jiang; Min Xu; Yang Liu; Rui Qi; Xiaolong Qi; Xiantao Sun; Ping Xie; Qinghuai Liu; Biao Yan; Xunlun Sheng; Chen Zhao
TAGS: mutation, retinal degeneration, cilia, proteins, ciliopathies
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4581-4589. doi: 10.1167/iovs.17-23351

Includes: Supplemental Content

Low Vision September 2018

Predicting Visual Acuity From Visual Field Sensitivity in Age-Related Macular Degeneration

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Jonathan Denniss; Helen C. Baggaley; Andrew T. Astle
TAGS: visual acuity, visual fields, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4590-4597. doi: 10.1167/iovs.18-24861

Clinical and Epidemiologic Research September 2018

Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore

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Yee-Ling Wong; Charumathi Sabanayagam; Yang Ding; Chee-Wai Wong; Anna Chwee-Hong Yeo; Yin-Bun Cheung; Gemmy Cheung; Audrey Chia; Kyoko Ohno-Matsui; Tien-Yin Wong; Jie Jin Wang; Ching-Yu Cheng; Quan V. Hoang; Ecosse Lamoureux; Seang-Mei Saw
TAGS: adult, eye diseases, myopia, risk factors, singapore, vision, visual impairment, eye, prevalence, fundus photography, myopic macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4603-4613. doi: 10.1167/iovs.18-24032

Visual Psychophysics and Physiological Optics September 2018

Sensitivity to S-Cone Stimuli and the Development of Myopia

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Christopher Patrick Taylor; Timothy G. Shepard; Frances J. Rucker; Rhea T. Eskew, Jr
TAGS: retinal cone, myopia, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4622-4630. doi: 10.1167/iovs.18-24113

New Developments in Vision Research September 2018

Translational Retinal Research and Therapies

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Alison J. Hardcastle; Paul A. Sieving; José-Alain Sahel; Samuel G. Jacobson; Artur V. Cideciyan; John G. Flannery; William A. Beltran; Gustavo D. Aguirre
TAGS: gene therapy, mutation, blindness, retinal cone, dog, domestic, genes, genome, animal model, photoreceptors, retinal degeneration, retinitis pigmentosa, rhodopsin, rod photoreceptors, vision, mice, proteins, retina, leber's amaurosis, spatial vectors, optogenetics
Trans. Vis. Sci. Tech.. 2018; 7(5):8. doi: 10.1167/tvst.7.5.8

Articles September 2018

Pattern Electroretinogram Detects Localized Glaucoma Defects

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Tommaso Salgarello; Andrea Giudiceandrea; Luigi Calandriello; Dario Marangoni; Alberto Colotto; Aldo Caporossi; Benedetto Falsini
TAGS: glaucoma, electroretinography
Trans. Vis. Sci. Tech.. 2018; 7(5):6. doi: 10.1167/tvst.7.5.6

Retina September 2018

Low-Level Nighttime Light Therapy for Age-Related Macular Degeneration: A Randomized Clinical Trial

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D. Grant Robinson; Tom H. Margrain; Matt J. Dunn; Clare Bailey; Alison M. Binns
TAGS: clinical trials, drusen, dark adaptation, disease progression, masks, phototherapy, safety, ultraviolet therapy, eye, age-related macular degeneration, ranibizumab, outcome measures
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4531-4541. doi: 10.1167/iovs.18-24284

Includes: Supplemental Content

Retina September 2018

Progression in X-linked Retinitis Pigmentosa Due to ORF15-RPGR Mutations: Assessment of Localized Vision Changes Over 2 Years

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Artur V. Cideciyan; Jason Charng; Alejandro J. Roman; Rebecca Sheplock; Alexandra V. Garafalo; Elise Heon; Samuel G. Jacobson
TAGS: gene therapy, mutation, retinal cone, perimetry, retinitis pigmentosa, vision, visual fields, x-linked inheritance, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4558-4566. doi: 10.1167/iovs.18-24931

Includes: Supplemental Content

Special Issue September 2018

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy

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Imran A. Bhutto; Shuntaro Ogura; Rajkumar Baldeosingh; D. Scott McLeod; Gerard A. Lutty; Malia M. Edwards
TAGS: phenotype, atrophy, injections, photoreceptors, wounds and injuries, eye, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD143-AMD151. doi: 10.1167/iovs.18-24245

Includes: Supplemental Content

Article September 2018

Evidence for chromatic edge detectors in human vision using classification images

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William McIlhagga; Kathy T. Mullen
TAGS: color, retinal cone, vision, noise, filters, weight measurement scales, luminance
Journal of Vision. 2018; 18(9):8. doi: 10.1167/18.9.8

Includes: Supplemental Content

Anatomy and Pathology/Oncology September 2018

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

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Zachary K. Goldsmith; William Coppess; Andrew S. Irvine; Kelley Yuan; Samuel R. Barsh; Madison K. Ritter; Matthew W. McEwen; Jacqueline Flores-Otero; Aileen Garcia-Vargas; Magaly Martinez-Ferrer; Rachel C. Brennan; Vanessa M. Morales-Tirado; Matthew W. Wilson
TAGS: signal transduction, cell culture techniques, western blotting, enzyme-linked immunosorbent assay, blood platelets, cell proliferation, flow cytometry, cell lines, cell survival, platelet-derived growth factor, platelet-derived growth factor receptor, retinoblastoma, rna, messenger, seeds, spheroids, cellular, vitreous body, diagnostic imaging, eye, neoplasms, rna, small interfering, nuclear translocation, proto-oncogene proteins c-akt, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4486-4495. doi: 10.1167/iovs.18-24359

Retina September 2018

Three-Dimensional Microscopy Demonstrates Series and Parallel Organization of Human Peripapillary Capillary Plexuses

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Erandi Chandrasekera; Dong An; Ian L. McAllister; Dao-Yi Yu; Chandrakumar Balaratnasingam
TAGS: microcirculation, blood capillaries
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4327-4344. doi: 10.1167/iovs.18-24105

Retinal Cell Biology September 2018

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

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Nilisha Fernando; Yvette Wooff; Riemke Aggio-Bruce; Joshua A. Chu-Tan; Haihan Jiao; Catherine Dietrich; Matt Rutar; Melissa Rooke; Deepthi Menon; Janis T. Eells; Krisztina Valter; Philip G. Board; Jan Provis; Riccardo Natoli
TAGS: oxidative stress, photoreceptors, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4362-4374. doi: 10.1167/iovs.18-24627

Retinal Cell Biology September 2018

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

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Chloe N. Thomas; Adam M. Thompson; Eleanor McCance; Martin Berry; Ann Logan; Richard J. Blanch; Zubair Ahmed
TAGS: caspases, eye injuries, photoreceptors, retinal ganglion cells, wounds and injuries, ocular trauma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4453-4462. doi: 10.1167/iovs.18-24045

Includes: Supplemental Content

Retina September 2018

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

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Johnny Di Pierdomenico; Rebecca Scholz; F. Javier Valiente-Soriano; Maria C. Sánchez-Migallón; Manuel Vidal-Sanz; Thomas Langmann; Marta Agudo-Barriuso; Diego García-Ayuso; María Paz Villegas-Pérez
TAGS: ciliary neurotrophic factor, fibroblast growth factor 2, minocycline, animal model, photoreceptors, retinal degeneration, rats, neuroprotective effect
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4392-4403. doi: 10.1167/iovs.18-24621

Articles September 2018

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography

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Maryse Lapierre-Landry; Alison L. Huckenpahler; Brian A. Link; Ross F. Collery; Joseph Carroll; Melissa C. Skala
TAGS: melanins, zebrafish, diagnostic imaging, eye, mosaicism, retina, optical coherence tomography
Trans. Vis. Sci. Tech.. 2018; 7(5):4. doi: 10.1167/tvst.7.5.4

Articles September 2018

Ultrasound Imaging and Measurement of Choroidal Blood Flow

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Raksha Urs; Jeffrey A. Ketterling; Alfred C. H. Yu; Harriet O. Lloyd; Billy Y. S. Yiu; Ronald H. Silverman
TAGS: ultrasonography, vascular flow, choroid, diagnostic imaging, eye, transurethral ureterorenoscopy, fluid flow
Trans. Vis. Sci. Tech.. 2018; 7(5):5. doi: 10.1167/tvst.7.5.5

Articles August 2018

Handheld Retinal Oximetry in Healthy Young Adults

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Wouter Vehmeijer; Sveinn Hakon Hardarson; Kelly Jonkman; Leon Aarts; Albert Dahan; Einar Stefánsson; Nicoline Schalij-Delfos
TAGS: oximetry, supine position, oxygen saturation measurement, young adult, mobile devices
Trans. Vis. Sci. Tech.. 2018; 7(4):19. doi: 10.1167/tvst.7.4.19

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Cone Photoreceptor Cell Segmentation and Diameter Measurement on Adaptive Optics Images Using Circularly Constrained Active Contour Model

Retest Reliability of Mesopic and Dark-Adapted Microperimetry in Patients With Intermediate Age-Related Macular Degeneration and Age-Matched Controls

IFT52 as a Novel Candidate for Ciliopathies Involving Retinal Degeneration

Predicting Visual Acuity From Visual Field Sensitivity in Age-Related Macular Degeneration

Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore

Sensitivity to S-Cone Stimuli and the Development of Myopia

Translational Retinal Research and Therapies

Pattern Electroretinogram Detects Localized Glaucoma Defects

Low-Level Nighttime Light Therapy for Age-Related Macular Degeneration: A Randomized Clinical Trial

Progression in X-linked Retinitis Pigmentosa Due to ORF15-RPGR Mutations: Assessment of Localized Vision Changes Over 2 Years

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy

Evidence for chromatic edge detectors in human vision using classification images

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

Three-Dimensional Microscopy Demonstrates Series and Parallel Organization of Human Peripapillary Capillary Plexuses

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography

Ultrasound Imaging and Measurement of Choroidal Blood Flow

Handheld Retinal Oximetry in Healthy Young Adults

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