Retina

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Retina June 2019

Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence

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Alexander Sumaroka; Alexandra V. Garafalo; Evelyn P. Semenov; Rebecca Sheplock; Arun K. Krishnan; Alejandro J. Roman; Samuel G. Jacobson; Artur V. Cideciyan
TAGS: artificial intelligence, leber's amaurosis, mutation, retina, retinal cone, vision, fovea centralis, perimetry, machine learning
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2551-2562. doi: 10.1167/iovs.19-27156

Includes: Supplemental Content

Visual Neuroscience June 2019

Electrically Evoked Potentials Are Reduced Compared to Axon Numbers in Rhodopsin P347L Transgenic Rabbits With Severe Photoreceptor Degeneration

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Taro Kominami; Shinji Ueno; Kentaro Nishida; Daiki Inooka; Azusa Kominami; Mineo Kondo; Hiroko Terasaki
TAGS: axon, evoked potentials, optic nerve, oryctolagus cuniculus, photoreceptors, retinal degeneration, rhodopsin, tissue degeneration, animals, transgenic
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2543-2550. doi: 10.1167/iovs.19-26972

Articles June 2019

Reliability of Semiautomated Kinetic Perimetry (SKP) and Goldmann Kinetic Perimetry in Children and Adults With Retinal Dystrophies

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Claire S. Barnes; Ronald A. Schuchard; David G. Birch; Gislin Dagnelie; Leah Wood; Robert K. Koenekoop; Ava K. Bittner
TAGS: adult, child, kinetics, octopus, perimetry, reliability, retinal dystrophies
Trans. Vis. Sci. Tech.. 2019; 8(3):36. doi: 10.1167/tvst.8.3.36

Includes: Supplemental Content

Articles June 2019

Reliability of Spectral-Domain OCT Ellipsoid Zone Area and Shape Measurements in Retinitis Pigmentosa

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Travis B. Smith; Maria A. Parker; Peter N. Steinkamp; Albert Romo; Laura R. Erker; Brandon J. Lujan; Ning Smith
TAGS: face, reliability, retinitis pigmentosa, shape, spectral-domain optical coherence tomography
Trans. Vis. Sci. Tech.. 2019; 8(3):37. doi: 10.1167/tvst.8.3.37

Includes: Supplemental Content

Retina June 2019

Longitudinal Association Between Drusen Volume and Retinal Capillary Perfusion in Intermediate Age-Related Macular Degeneration

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Gregor Sebastian Reiter; Reinhard Told; Ferdinand Georg Schlanitz; Lukas Baumann; Ursula Schmidt-Erfurth; Stefan Sacu
TAGS: age-related macular degeneration, blood capillaries, drusen, perfusion, volume, follow-up
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2503-2508. doi: 10.1167/iovs.18-26237

Retina June 2019

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

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Lara S. Carroll; Hironori Uehara; Daniel Fang; Susie Choi; Xiaohui Zhang; Malkit Singh; Zoya Sandhu; Philip M. Cummins; Tim M. Curtis; Alan W. Stitt; Bonnie J. Archer; Balamurali K. Ambati
TAGS: angiotensin i, blood capillaries, diabetes mellitus, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2494-2502. doi: 10.1167/iovs.18-26182

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging June 2019

Impaired Retinal Vascular Reactivity in Diabetic Retinopathy as Assessed by Optical Coherence Tomography Angiography

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Bright S. Ashimatey; Kyle M. Green; Zhongdi Chu; Ruikang K. Wang; Amir H. Kashani
TAGS: angiogram, diabetic retinopathy, hypercapnia, hyperoxia, optical coherence tomography, blood capillaries, ventricular septal defect, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2468-2473. doi: 10.1167/iovs.18-26417

Retina June 2019

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

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J. Alan Gambril; Kenneth R. Sloan; Thomas A. Swain; Carrie Huisingh; Anna V. Zarubina; Jeffrey D. Messinger; Thomas Ach; Christine A. Curcio
TAGS: age-related macular degeneration, autofluorescence, phenotype, retinal pigment epithelium, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2481-2493. doi: 10.1167/iovs.19-26949

Includes: Supplemental Content

Articles June 2019

Determinants of Macular Layers and Optic Disc Characteristics on SD-OCT: The Rhineland Study

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Matthias M. Mauschitz; Frank G. Holz; Robert P. Finger; Monique M. B. Breteler
TAGS: cerebrovascular accident, ischemic stroke, glaucoma, optic disk, spectral-domain optical coherence tomography
Trans. Vis. Sci. Tech.. 2019; 8(3):34. doi: 10.1167/tvst.8.3.34

Includes: Supplemental Content

Article June 2019

Switch rates for orthogonally oriented kinetic-depth displays are correlated across observers

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Alexander Pastukhov; Philipp Kastrup; Isabel Friederike Abs; Claus-Christian Carbon
TAGS: carbon, kinetics
Journal of Vision. 2019; 19(6):1. doi: 10.1167/19.6.1

Includes: Multimedia, Supplemental Content

Articles May 2019

Automated Measurement of the Foveal Avascular Zone in Swept-Source Optical Coherence Tomography Angiography Images

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Hirokazu Ishii; Takuhei Shoji; Yuji Yoshikawa; Junji Kanno; Hisashi Ibuki; Kei Shinoda
TAGS: angiogram, optical coherence tomography
Trans. Vis. Sci. Tech.. 2019; 8(3):28. doi: 10.1167/tvst.8.3.28

Articles May 2019

Smartphone-Based, Rapid, Wide-Field Fundus Photography for Diagnosis of Pediatric Retinal Diseases

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Tapan P. Patel; Tyson N. Kim; Gina Yu; Vaidehi S. Dedania; Philip Lieu; Cynthia X. Qian; Cagri G. Besirli; Hakan Demirci; Todd Margolis; Daniel A. Fletcher; Yannis M. Paulus
TAGS: child, pediatrics, retinal diseases, diagnostic imaging, retina, fundus photography, cell phones, quality, diagnostic imaging of retina
Trans. Vis. Sci. Tech.. 2019; 8(3):29. doi: 10.1167/tvst.8.3.29

Articles May 2019

Transplantation of Mature Photoreceptors in Rodents With Retinal Degeneration

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Henri Lorach; Seungbum Kang; Mohajeet B. Bhuckory; Alix Trouillet; Roopa Dalal; Michael Marmor; Daniel Palanker
TAGS: photoreceptors, retinal degeneration, rodentia, tissue transplants, retina, transplantation
Trans. Vis. Sci. Tech.. 2019; 8(3):30. doi: 10.1167/tvst.8.3.30

Includes: Multimedia, Supplemental Content

Articles May 2019

Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System

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Tai-Chi Lin; Lei-Chi Wang; Lan Yue; Yi Zhang; Paulo Falabella; Danhong Zhu; David R. Hinton; Narsing A. Rao; David G. Birch; Rand Spencer; Jessy D. Dorn; Mark S. Humayun
TAGS: eye, optic nerve, retina, histopathology tests, implants, visual prosthesis
Trans. Vis. Sci. Tech.. 2019; 8(3):31. doi: 10.1167/tvst.8.3.31

Articles May 2019

ReLayer: a Free, Online Tool for Extracting Retinal Thickness From Cross-Platform OCT Images

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Giovanni Ometto; Ismail Moghul; Giovanni Montesano; Andrew Hunter; Nikolas Pontikos; Pete R. Jones; Pearse A. Keane; Xiaoxuan Liu; Alastair K. Denniston; David P. Crabb
TAGS: engineering, tissue membrane, reference standards, research personnel, software, eye, reliability, optical coherence tomography, pixel, retinal pigment epithelium, clinicians, datasets
Trans. Vis. Sci. Tech.. 2019; 8(3):25. doi: 10.1167/tvst.8.3.25

Includes: Supplemental Content

Biochemistry and Molecular Biology May 2019

REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice

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William P. Miller; Allyson L. Toro; Alistair J. Barber; Michael D. Dennis
TAGS: oxidative stress, diabetes mellitus, hyperglycemia, glucose, cell death, feedback, mice, proteins, retina, glycogen synthase kinase 3, proto-oncogene proteins c-akt, hyperglycemic agents
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2369-2379. doi: 10.1167/iovs.19-26606

Genetics May 2019

Characteristic Ocular Features in Cases of Autosomal Recessive PROM1 Cone-Rod Dystrophy

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Frederick T. Collison; Gerald A. Fishman; Takayuki Nagasaki; Jana Zernant; J. Jason McAnany; Jason C. Park; Rando Allikmets
TAGS: color, electroretinography, family, retinitis pigmentosa, diagnostic imaging, autosomal recessive inheritance, genetic analysis, progressive cone-rod dystrophy, autofluorescence, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2347-2356. doi: 10.1167/iovs.19-26993

Visual Neuroscience May 2019

Impact of Diabetic Retinopathy on Sleep, Mood, and Quality of Life

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Rupal Morjaria; Iona Alexander; Robert M. J. Purbrick; Rukhsana Safa; Ngaihang Victor Chong; Katharina Wulff; Russell G. Foster; Susan M. Downes; for the SOMNUS Study Group
TAGS: diabetic retinopathy, quality of life, sleep, mood, sleep quality
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2304-2310. doi: 10.1167/iovs.18-26108

Retina May 2019

Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR

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Jakob Grauslund; Ulrik Frydkjaer-Olsen; Tunde Peto; Jimena Fernández-Carneado; Berta Ponsati; Cristina Hernández; José Cunha-Vaz; Rafael Simó; for the EUROCONDOR
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, dilatation, pathologic, somatostatin, brimonidine, retinal vascular caliber
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2257-2262. doi: 10.1167/iovs.18-26487

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology May 2019

Head and Gaze Behavior in Retinitis Pigmentosa

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Samuel A. Titchener; Lauren N. Ayton; Carla J. Abbott; James B. Fallon; Mohit N. Shivdasani; Emily Caruso; Pyrawy Sivarajah; Matthew A. Petoe
TAGS: head movements, pursuit, smooth, retinitis pigmentosa, saccades, eye, gaze
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2263-2273. doi: 10.1167/iovs.18-26121

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Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence

Electrically Evoked Potentials Are Reduced Compared to Axon Numbers in Rhodopsin P347L Transgenic Rabbits With Severe Photoreceptor Degeneration

Reliability of Semiautomated Kinetic Perimetry (SKP) and Goldmann Kinetic Perimetry in Children and Adults With Retinal Dystrophies

Reliability of Spectral-Domain OCT Ellipsoid Zone Area and Shape Measurements in Retinitis Pigmentosa

Longitudinal Association Between Drusen Volume and Retinal Capillary Perfusion in Intermediate Age-Related Macular Degeneration

Intravitreal AAV2.COMP-Ang1 Attenuates Deep Capillary Plexus Expansion in the Aged Diabetic Mouse Retina

Impaired Retinal Vascular Reactivity in Diabetic Retinopathy as Assessed by Optical Coherence Tomography Angiography

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

Determinants of Macular Layers and Optic Disc Characteristics on SD-OCT: The Rhineland Study

Switch rates for orthogonally oriented kinetic-depth displays are correlated across observers

Automated Measurement of the Foveal Avascular Zone in Swept-Source Optical Coherence Tomography Angiography Images

Smartphone-Based, Rapid, Wide-Field Fundus Photography for Diagnosis of Pediatric Retinal Diseases

Transplantation of Mature Photoreceptors in Rodents With Retinal Degeneration

Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System

ReLayer: a Free, Online Tool for Extracting Retinal Thickness From Cross-Platform OCT Images

REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice

Characteristic Ocular Features in Cases of Autosomal Recessive PROM1 Cone-Rod Dystrophy

Impact of Diabetic Retinopathy on Sleep, Mood, and Quality of Life

Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR

Head and Gaze Behavior in Retinitis Pigmentosa

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