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Multidisciplinary Ophthalmic Imaging September 2021

Impact of Structural Changes on Multifocal Electroretinography in Patients With Use of Hydroxychloroquine

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Enrico Borrelli; Marco Battista; Maria Lucia Cascavilla; Chiara Viganò; Federico Borghesan; Nicolò Nicolini; Lidia Clemente; Riccardo Sacconi; Costanza Barresi; Alessandro Marchese; Elisabetta Miserocchi; Giulio Modorati; Francesco Bandello; Giuseppe Querques
TAGS: electroretinography, hydroxychloroquine, retinal diseases, toxic effect, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):28. doi: https://doi.org/10.1167/iovs.62.12.28

Includes: Supplemental Content

Special Issue September 2021

A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Interim Clinical Trial Results

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Matthew A. Petoe; Samuel A. Titchener; Maria Kolic; William G. Kentler; Carla J. Abbott; David A. X. Nayagam; Elizabeth K. Baglin; Jessica Kvansakul; Nick Barnes; Janine G. Walker; Stephanie B. Epp; Kiera A. Young; Lauren N. Ayton; Chi D. Luu; Penelope J. Allen; for the Bionics Institute and Centre for Eye Research Australia Retinal Prosthesis Consortium
TAGS: prostheses, surgical procedures, operative, vision, visual prosthesis, eye, mobility, touch sensation, bionics, avoidance behavior
Trans. Vis. Sci. Tech.. 2021; 10(10):12. doi: https://doi.org/10.1167/tvst.10.10.12

Includes: Supplemental Content

Articles September 2021

Retinal Vascular Resistance Significantly Correlates With Visual Acuity After 1 Year of Anti-VEGF Therapy in Central Retinal Vein Occlusion

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Makiko Matsumoto; Kiyoshi Suzuma; Fumito Akiyama; Kanako Yamada; Shiori Harada; Eiko Tsuiki; Takashi Kitaoka
TAGS: anti-vascular endothelial growth factor therapy, central retinal vein occlusion, vascular resistance, visual acuity, injections
Trans. Vis. Sci. Tech.. 2021; 10(11):19. doi: https://doi.org/10.1167/tvst.10.11.19

Articles September 2021

Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography

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Shin Kadomoto; Yuki Muraoka; Akihito Uji; Sotaro Ooto; Kentaro Kawai; Masaharu Ishikura; Naomi Nishigori; Tadamichi Akagi; Akitaka Tsujikawa
TAGS: diagnostic imaging, optical coherence tomography, optics, retinal cone, retina, fovea centralis, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2021; 10(11):17. doi: https://doi.org/10.1167/tvst.10.11.17

Retina September 2021

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

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Yinting Song; Mengyu Liao; Xiao Zhao; Han Han; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: macrophages, massively-parallel genome sequencing, mucopolysaccharidoses, retinal pigment cell, vitreous body, cell-derived microparticles, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):26. doi: https://doi.org/10.1167/iovs.62.12.26

Includes: Supplemental Content

Perspective September 2021

Coming of Age for the Photoreceptor Synapse

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Ellen Townes-Anderson; Eva Halasz; Weiwei Wang; Marco Zarbin
TAGS: photoreceptors, retinal cone, retinal detachment, rod photoreceptors, synapses, wounds and injuries, retina, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):24. doi: https://doi.org/10.1167/iovs.62.12.24

Retina September 2021

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X 7 in the Diabetic Retina

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Jin-Sang Yu; Jad Daw; Jose-Andres C. Portillo; Carlos S. Subauste
TAGS: cd40 antigens, diabetes mellitus, endothelial cells, intercellular adhesion molecule 1, retina, up-regulation (physiology), tumor necrosis factors, cytokine, diabetic retinopathy, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):22. doi: https://doi.org/10.1167/iovs.62.12.22

Retina September 2021

Impacts of Systemic Hypertension on the Macular Microvasculature in Diabetic Patients Without Clinical Diabetic Retinopathy

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Min-Woo Lee; Hyung-Moon Koo; Woo-Hyuk Lee; Jae-Hyeong Park; Young-Hoon Lee; Jung-Yeul Kim
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, hypertension, macular vasculature, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):21. doi: https://doi.org/10.1167/iovs.62.12.21

Retina September 2021

Retinal Degeneration Caused by Ago2 Disruption

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Xue-Jiao Chen; Chang-Jun Zhang; Ya-Han Wang; Zi-Bing Jin
TAGS: mice, retina, retinal degeneration, micrornas
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):14. doi: https://doi.org/10.1167/iovs.62.12.14

Includes: Supplemental Content

Articles September 2021

Deep-Learning–Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study

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Vincent Yuen; Anran Ran; Jian Shi; Kaiser Sham; Dawei Yang; Victor T. T. Chan; Raymond Chan; Jason C. Yam; Clement C. Tham; Gareth J. McKay; Michael A. Williams; Leopold Schmetterer; Ching-Yu Cheng; Vincent Mok; Christopher L. Chen; Tien Y. Wong; Carol Y. Cheung
TAGS: datasets, deep learning, eye, handedness, image quality, multicenter studies, macula lutea, optics, eye diseases
Trans. Vis. Sci. Tech.. 2021; 10(11):16. doi: https://doi.org/10.1167/tvst.10.11.16

Includes: Multimedia, Supplemental Content

Articles September 2021

AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

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Carina M. Weigelt; Holger Fuchs; Tanja Schönberger; Birgit Stierstorfer; Benjamin Strobel; Thorsten Lamla; Thomas Ciossek; Remko A. Bakker; Norbert H. Redemann
TAGS: eye, interleukin-6, mice, retinal diseases, tumor necrosis factors, vascular endothelial growth factor a, injections, pathology, inflammation, retina
Trans. Vis. Sci. Tech.. 2021; 10(11):15. doi: https://doi.org/10.1167/tvst.10.11.15

Includes: Supplemental Content

Retina September 2021

Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

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Bhubanananda Sahu; Laura Moreno Leon; Wei Zhang; Nikita Puranik; Ramesh Periasamy; Hemant Khanna; Michael Volkert
TAGS: gene therapy, injections, mice, nerve degeneration, oxidative stress, retinal degeneration, retinal diseases, photoreceptors, caspases, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):8. doi: https://doi.org/10.1167/iovs.62.12.8

Includes: Supplemental Content

Glaucoma September 2021

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

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Yuri Fujino; Ryo Asaoka; Hiroshi Murata; Takehiro Yamashita
TAGS: central retinal artery, glaucoma, intraocular pressure, optic disk, retina, visual fields, maximum tolerated dose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):6. doi: https://doi.org/10.1167/iovs.62.12.6

Articles September 2021

Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes

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Sheng Chen; Meiwen Tian; Liang Zhang; Chenli Hu; Ke Liu; Bo Qin; Shenwen Liu
TAGS: eye, follow-up, implantation procedure, retinal detachment, vitreous body, silicone oils, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2021; 10(11):8. doi: https://doi.org/10.1167/tvst.10.11.8

Includes: Multimedia, Supplemental Content

Retina September 2021

Progressive Dysmorphia of Retinal Pigment Epithelium in Age-Related Macular Degeneration Investigated by Fluorescence Lifetime Imaging

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Martin Hammer; Juliane Jakob-Girbig; Linda Schwanengel; Christine A. Curcio; Somar Hasan; Daniel Meller; Rowena Schultz
TAGS: age-related macular degeneration, diagnostic imaging, fluorescence, hyperpigmentation, retinal pigment epithelium, atrophy
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):2. doi: https://doi.org/10.1167/iovs.62.12.2

Special Issue September 2021

In Vivo Subretinal ARPE-19 Cell Tracking Using Indocyanine Green Contrast-Enhanced Multimodality Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence Imaging for Regenerative Medicine

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Van Phuc Nguyen; Yanxiu Li; Jessica Henry; Thomas Qian; Wei Zhang; Xueding Wang; Yannis M. Paulus
TAGS: diagnostic imaging, fluorescence, indocyanine green, injections, optical coherence tomography, cell tracking, regenerative medicine
Trans. Vis. Sci. Tech.. 2021; 10(10):10. doi: https://doi.org/10.1167/tvst.10.10.10

Articles September 2021

Macular Rod Function in Retinitis Pigmentosa Measured With Scotopic Microperimetry

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Arun K. Krishnan; Alejandro J. Roman; Malgorzata Swider; Samuel G. Jacobson; Artur V. Cideciyan
TAGS: retinitis pigmentosa, rod photoreceptors, dynamic range
Trans. Vis. Sci. Tech.. 2021; 10(11):3. doi: https://doi.org/10.1167/tvst.10.11.3

Retina August 2021

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

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Dongfeng Cao; Belinda Leong; Jeffrey D. Messinger; Deepayan Kar; Thomas Ach; Lawrence A. Yannuzzi; K. Bailey Freund; Christine A. Curcio
TAGS: age-related macular degeneration, atrophic condition of skin, atrophy, cell transdifferentiation, diagnostic imaging, donors, eye, immunohistochemistry, optical coherence tomography, phenotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):34. doi: https://doi.org/10.1167/iovs.62.10.34

Includes: Supplemental Content

Articles August 2021

Association Between Retinal Artery Angle and Visual Function in Eyes With Idiopathic Epiretinal Membrane

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Koichi Nagura; Tatsuya Inoue; Han Peng Zhou; Ryo Obata; Ryo Asaoka; Rei Arasaki; Akinori Sato; Kentaro Nakamura; Masaru Takeuchi; Shin Tanaka; Yasuo Yanagi; Maiko Maruyama-Inoue; Kazuaki Kadonosono
TAGS: central retinal artery, epiretinal membrane, eye, vision, metamorphopsias
Trans. Vis. Sci. Tech.. 2021; 10(9):35. doi: https://doi.org/10.1167/tvst.10.9.35

Articles August 2021

Manual Versus Semi-Automated Measurement of Geographic Atrophy Area in Eyes With Age-Related Macular Degeneration

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Raziyeh Mahmoudzadeh; Mirataollah Salabati; M. Ali Khan; Sunir J. Garg; Jason Hsu
TAGS: age-related macular degeneration, atrophy, eye, homogeneity, software
Trans. Vis. Sci. Tech.. 2021; 10(9):33. doi: https://doi.org/10.1167/tvst.10.9.33

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Impact of Structural Changes on Multifocal Electroretinography in Patients With Use of Hydroxychloroquine

A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Interim Clinical Trial Results

Retinal Vascular Resistance Significantly Correlates With Visual Acuity After 1 Year of Anti-VEGF Therapy in Central Retinal Vein Occlusion

Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

Coming of Age for the Photoreceptor Synapse

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X 7 in the Diabetic Retina

Impacts of Systemic Hypertension on the Macular Microvasculature in Diabetic Patients Without Clinical Diabetic Retinopathy

Retinal Degeneration Caused by Ago2 Disruption

Deep-Learning–Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study

AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes

Progressive Dysmorphia of Retinal Pigment Epithelium in Age-Related Macular Degeneration Investigated by Fluorescence Lifetime Imaging

In Vivo Subretinal ARPE-19 Cell Tracking Using Indocyanine Green Contrast-Enhanced Multimodality Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence Imaging for Regenerative Medicine

Macular Rod Function in Retinitis Pigmentosa Measured With Scotopic Microperimetry

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

Association Between Retinal Artery Angle and Visual Function in Eyes With Idiopathic Epiretinal Membrane

Manual Versus Semi-Automated Measurement of Geographic Atrophy Area in Eyes With Age-Related Macular Degeneration

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