Retina

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Retinal Cell Biology October 2019

Activation of Sigma 1 Receptor Extends Survival of Cones and Improves Visual Acuity in a Murine Model of Retinitis Pigmentosa

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Jing Wang; Alan Saul; Sylvia B. Smith
TAGS: ligands, mice, retinal cone, visual acuity, retinitis pigmentosa, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4397-4407. doi: 10.1167/iovs.19-27709

Includes: Supplemental Content

Retinal Cell Biology October 2019

Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

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Paul Ikgan Sia; John P. M. Wood; Glyn Chidlow; Robert Casson
TAGS: creatine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4360-4377. doi: 10.1167/iovs.18-25858

Includes: Supplemental Content

Retinal Cell Biology October 2019

Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

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Wanting Shu; Bailey H. Baumann; Ying Song; Yingrui Liu; Xingwei Wu; Joshua L. Dunaief
TAGS: injections, iron, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4378-4387. doi: 10.1167/iovs.19-28250

Article October 2019

Contributions of foveal and non-foveal retina to the human eye's focusing response

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Vivek Labhishetty; Steven A. Cholewiak; Martin S. Banks
TAGS: myopia, retina, visual accommodation, diameter, eye, fovea centralis
Journal of Vision. 2019; 19(12):18. doi: 10.1167/19.12.18

Includes: Supplemental Content

Articles October 2019

Evaluation of Cytotoxicity of Perfluorocarbons for Intraocular Use by Cytotoxicity Test In Vitro in Cell Lines and Human Donor Retina Ex Vivo

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Mario R Romano; Mariantonia Ferrara; Claudio Gatto; Barbara Ferrari; Laura Giurgola; Jana D'Amato Tóthová
TAGS: cell lines, cytotoxicity, donors, fluorocarbons, patent foramen ovale, retina, international organization for standardization
Trans. Vis. Sci. Tech.. 2019; 8(5):24. doi: 10.1167/tvst.8.5.24

Includes: Multimedia, Supplemental Content

Articles October 2019

Fully Automated Estimation of Spacing and Density for Retinal Mosaics

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Robert F. Cooper; Geoffrey K. Aguirre; Jessica I. W. Morgan
TAGS: mosaicism, retinal cone, photoreceptors
Trans. Vis. Sci. Tech.. 2019; 8(5):26. doi: 10.1167/tvst.8.5.26

Retina October 2019

Retinal Nonperfusion Relationship to Arteries or Veins Observed on Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy

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Akihiro Ishibazawa; Lucas R. De Pretto; A. Yasin Alibhai; Eric M. Moult; Malvika Arya; Osama Sorour; Nihaal Mehta; Caroline R. Baumal; Andre J. Witkin; Akitoshi Yoshida; Jay S. Duker; James G. Fujimoto; Nadia K. Waheed
TAGS: angiogram, blood capillaries, diabetes mellitus, diabetic retinopathy, eye, nonproliferative diabetic retinopathy, optical coherence tomography, central retinal artery
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4310-4318. doi: 10.1167/iovs.19-26653

Includes: Supplemental Content

Retina October 2019

Effect of Choroidal Vessel Density on the Ellipsoid Zone and Visual Function in Retinitis Pigmentosa Using Optical Coherence Tomography Angiography

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Ruyuan Liu; Jing Lu; Qiuhui Liu; Yishen Wang; Di Cao; Jing Wang; Xiao Wang; Jianying Pan; Li Ma; Chenjin Jin; SriniVas Sadda; Yan Luo; Lin Lu
TAGS: angiogram, optical coherence tomography, retinitis pigmentosa, vision, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4328-4335. doi: 10.1167/iovs.18-24921

Retina October 2019

Late-Onset Stargardt Disease Due to Mild, Deep-Intronic ABCA4 Alleles

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Esmee H. Runhart; Dyon Valkenburg; Stéphanie S. Cornelis; Mubeen Khan; Riccardo Sangermano; Silvia Albert; Nathalie M. Bax; Galuh D. N. Astuti; Christian Gilissen; Jan-Willem R. Pott; Joke B. G. M. Verheij; Ellen A. W. Blokland; Frans P. M. Cremers; L. Ingeborgh van den Born; Carel B. Hoyng
TAGS: alleles, introns, penetrance, genetic, stargardt's disease, cohort studies, photoreceptors, age of onset, stem cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4249-4256. doi: 10.1167/iovs.19-27524

Includes: Supplemental Content

Physiology and Pharmacology October 2019

Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice

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Jiaxin Xiao; Muhammed Yasin Adil; Karen Chang; Zicheng Yu; Lanbo Yang; Tor P. Utheim; Dong Feng Chen; Kin-Sang Cho
TAGS: contrast sensitivity, electroretinography, mice, retinal degeneration, rhodopsin, spatial vision, retinal cone, mice, knockout
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4196-4204. doi: 10.1167/iovs.19-26966

Retina October 2019

miR-590-3p Inhibits Pyroptosis in Diabetic Retinopathy by Targeting NLRP1 and Inactivating the NOX4 Signaling Pathway

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Chufeng Gu; Deji Draga; Chuandi Zhou; Tong Su; Chen Zou; Qing Gu; Tashi Lahm; Zhi Zheng; Qinghua Qiu
TAGS: diabetic retinopathy, nadph oxidase 4, pyroptosis, caspase-1, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4215-4223. doi: 10.1167/iovs.19-27825

Includes: Supplemental Content

Retina October 2019

Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury

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Matthew M. Harper; Addison W. Woll; Lucy P. Evans; Michael Delcau; Abhigna Akurathi; Adam Hedberg-Buenz; Dana A. Soukup; Nickolas Boehme; Marco M. Hefti; Laura M. Dutca; Michael G. Anderson; Alexander G. Bassuk
TAGS: basic local alignment search tool, blast injuries, mice, wounds and injuries, nerve degeneration, retinal ganglion cells, prevention, rna
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4159-4170. doi: 10.1167/iovs.19-27565

Includes: Supplemental Content

Retina October 2019

Induced Expression of VEGFC , ANGPT , and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy

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Yaping Li; Dong Chen; Luguo Sun; Yannan Wu; Ying Zou; Chen Liang; Yongli Bao; Jingwen Yi; Yu Zhang; Jing Hou; Zhen Li; Fengyun Yu; Yanxin Huang; Chunlei Yu; Lei Liu; Zaoxia Liu; Yi Zhang; Yuxin Li
TAGS: diabetes mellitus, type 2, genes, neovascularization, pathologic, proliferative diabetic retinopathy, retina, vascular endothelial growth factor c, gene expression, vascular endothelial growth factor a, rna, growth factor
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4084-4096. doi: 10.1167/iovs.19-26767

Includes: Supplemental Content

Retina October 2019

Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy

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Erlend C. S. Landsend; Hilde R. Pedersen; Øygunn A. Utheim; Corina S. Rueegg; Rigmor C. Baraas; Neil Lagali; Ragnheidur Bragadóttir; Morten C. Moe; Tor P. Utheim
TAGS: aniridia, foveal hypoplasia, fundus autofluorescence imaging, scanning laser ophthalmoscopy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4120-4128. doi: 10.1167/iovs.19-26994

Includes: Supplemental Content

Articles October 2019

Acute Rabbit Eye Model for Testing Subretinal Prostheses

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Ying Xiao; Yuqin Wang; Fangting Li; Tiezhu Lin; Kristyn Huffman; Stephanie Landeros; Brandon Bosse; Yi Jing; Dirk-Uwe Bartsch; Scott Thorogood; William R. Freeman; Lingyun Cheng
TAGS: eye, implantation procedure, oryctolagus cuniculus, prostheses, retina, implants, postoperative care
Trans. Vis. Sci. Tech.. 2019; 8(5):20. doi: 10.1167/tvst.8.5.20

Includes: Multimedia, Supplemental Content

Visual Neuroscience September 2019

Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells

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Johnnie M. Moore-Dotson; Erika D. Eggers
TAGS: amacrine cells, diabetes mellitus, gamma-aminobutyric acid, retinal bipolar cells, rod photoreceptors, diabetes mellitus, type 2
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4063-4073. doi: 10.1167/iovs.19-27137

Retina September 2019

Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration

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Maximilian Pfau; Leon von der Emde; Chantal Dysli; Sarah Thiele; Philipp T. Möller; Moritz Lindner; Jennifer Nadal; Matthias Schmid; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein
TAGS: age-related macular degeneration, atrophy, photophobia, false-positive results, perimetry, spectral-domain optical coherence tomography, frequency of responses
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3992-4001. doi: 10.1167/iovs.19-27178

Includes: Supplemental Content

Genetics September 2019

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

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Ebony Liu; Georgia Kaidonis; Bennet J. McComish; Mark C. Gillies; Sotoodeh Abhary; Rohan W. Essex; John H. Chang; Bishwanath Pal; Mark Daniell; Stewart Lake; Nikolai Petrovsky; Alex W. Hewitt; Alicia Jenkins; Ecosse L. Lamoureux; Jonathan M. Gleadle; Jamie E. Craig; Kathryn P. Burdon
TAGS: diabetes mellitus, type 1, diabetic retinopathy, genes, genetics, micrornas, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3937-3942. doi: 10.1167/iovs.18-25570

Includes: Supplemental Content

Retinal Cell Biology September 2019

Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy

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Ghulam Mohammad; Rakesh Radhakrishnan; Renu A. Kowluru
TAGS: diabetes mellitus, diabetic retinopathy, dna (cytosine-5-)-methyltransferase 1, dna, mitochondrial, epigenetics, glucose, mitochondria, quality control, dna, dna methylation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3943-3951. doi: 10.1167/iovs.19-27602

Retina September 2019

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

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Min-Woo Lee; Woo-Hyuk Lee; Gi-Seok Park; Hyung-Bin Lim; Jung-Yeul Kim
TAGS: hypertension, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3914-3919. doi: 10.1167/iovs.19-27652

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Activation of Sigma 1 Receptor Extends Survival of Cones and Improves Visual Acuity in a Murine Model of Retinitis Pigmentosa

Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

Contributions of foveal and non-foveal retina to the human eye's focusing response

Evaluation of Cytotoxicity of Perfluorocarbons for Intraocular Use by Cytotoxicity Test In Vitro in Cell Lines and Human Donor Retina Ex Vivo

Fully Automated Estimation of Spacing and Density for Retinal Mosaics

Retinal Nonperfusion Relationship to Arteries or Veins Observed on Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy

Effect of Choroidal Vessel Density on the Ellipsoid Zone and Visual Function in Retinitis Pigmentosa Using Optical Coherence Tomography Angiography

Late-Onset Stargardt Disease Due to Mild, Deep-Intronic ABCA4 Alleles

Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice

miR-590-3p Inhibits Pyroptosis in Diabetic Retinopathy by Targeting NLRP1 and Inactivating the NOX4 Signaling Pathway

Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury

Induced Expression of VEGFC , ANGPT , and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy

Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy

Acute Rabbit Eye Model for Testing Subretinal Prostheses

Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells

Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

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