Vitreous Disorders

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Articles April 2019

Relationship Between Neutralizing Antibodies Against Adeno-Associated Virus in the Vitreous and Serum: Effects on Retinal Gene Therapy

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Suhwan Lee; Im Kyeung Kang; Ji Hyun Kim; Bok Kyoung Jung; Keerang Park; Heesoon Chang; Joo Yong Lee; Heuiran Lee
TAGS: gene therapy, vitreous body, adeno-associated virus, neutralizing antibodies, serotype
Trans. Vis. Sci. Tech.. 2019; 8(2):14. doi: 10.1167/tvst.8.2.14

Includes: Supplemental Content

Lecture April 2019

Discovering Mechanisms in the Changing and Diverse Pathology of Retinopathy of Prematurity: The Weisenfeld Award Lecture

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M. Elizabeth Hartnett
TAGS: vascular endothelial growth factor a, signal transduction, awards and prizes, neovascularization, pathologic, retinopathy of prematurity, pathology, retina, vitreous neovascularization
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1286-1297. doi: 10.1167/iovs.18-25525

Immunology and Microbiology April 2019

Mycoplasma Ocular Infection in Subretinal Graft Transplantation of iPS Cells-Derived Retinal Pigment Epithelial Cells

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Kenichi Makabe; Sunao Sugita; Ayumi Hono; Hiroyuki Kamao; Masayo Takahashi
TAGS: cercopithecidae, tissue transplants, mycoplasma, transplantation, retinal pigment cell, idiopathic pneumonia syndrome, mycoplasma infections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1298-1308. doi: 10.1167/iovs.18-26222

Includes: Supplemental Content

Articles February 2019

Biological Characteristics of Subsilicone Oil Fluid and Differences With Other Ocular Humors

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Hideyuki Shimizu; Hiroki Kaneko; Ayana Suzumura; Kei Takayama; Rina Namba; Yasuhito Funahashi; Keiko Kataoka; Takeshi Iwase; Shiang-Jyi Hwang; Seina Ito; Kazuhisa Yamada; Shinji Ueno; Yasuki Ito; Hiroko Terasaki
TAGS: cytokine, electrolytes, cell survival, eye
Trans. Vis. Sci. Tech.. 2019; 8(1) doi: 10.1167/tvst.8.1.28

Includes: Supplemental Content

Physiology and Pharmacology February 2019

1 H NMR Spectroscopy Characterization of Porcine Vitreous Humor in Physiological and Photoreceptor Degeneration Conditions

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Alberto Elmi; Domenico Ventrella; Luca Laghi; Giacomo Carnevali; Chenglin Zhu; Grazia Pertile; Francesca Barone; Fabio Benfenati; Maria Laura Bacci
TAGS: photoreceptors, spectrum analysis, suidae, vitreous body, tissue degeneration, molecule
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):741-747. doi: 10.1167/iovs.18-25675

Includes: Supplemental Content

Articles February 2019

Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis

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Hiroyuki Nakashizuka; Hiroyuki Shimada; Takayuki Hattori; Koji Tanaka; Yorihisa Kitagawa; Kei Shinoda
TAGS: electroretinography, endophthalmitis, irrigation, povidone-iodine, vitrectomy, eye, intravitreal injections
Trans. Vis. Sci. Tech.. 2019; 8(1):21. doi: 10.1167/tvst.8.1.21

Articles February 2019

Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

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Justis P. Ehlers; Atsuro Uchida; Sunil K. Srivastava; Ming Hu
TAGS: intraoperative care, postoperative care, surgical procedures, operative, diagnostic imaging, eye, macular holes, volume, optical coherence tomography
Trans. Vis. Sci. Tech.. 2019; 8(1):18. doi: 10.1167/tvst.8.1.18

Retina January 2019

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

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Peter H. Tang; Gabriel Velez; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: mutation, exons, gelatinase a, surgical procedures, operative, vitreous body, eye, retina, cytokinesis, tissue degeneration, histopathology tests, proteolysis, proteins, splice-site mutation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):282-293. doi: 10.1167/iovs.18-25624

Includes: Supplemental Content

Genetics January 2019

Germline Mutations in CTNNB1 Associated With Syndromic FEVR or Norrie Disease

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Wenmin Sun; Xueshan Xiao; Shiqiang Li; Xiaoyun Jia; Panfeng Wang; Qingjiong Zhang
TAGS: mutation, germ-line mutation, familial exudative vitreoretinopathy, congenital progressive oculo-acoustico-cerebral degeneration, beta catenin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):93-97. doi: 10.1167/iovs.18-25142

Includes: Supplemental Content

Anatomy and Pathology/Oncology December 2018

Color and Temporal Frequency Sensitive Eye Growth in Chick

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Frances Rucker; Stephanie Britton; Christopher Taylor
TAGS: color, light, lighting, eye, photopsia, luminance, refraction
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6003-6013. doi: 10.1167/iovs.18-25322

Articles December 2018

Fluidics of Single and Double Blade Guillotine Vitrectomy Probes in Balanced Salt Solution and Artificial Vitreous

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Mario Rosario Romano; Alessandro Stocchino; Mariantonia Ferrara; Alberto Lagazzo; Rodolfo Repetto
TAGS: vitrectomy, vitreous body, velocity, unit of flow rate, fluid flow, particle image velocimetry, balanced salt solutions
Trans. Vis. Sci. Tech.. 2018; 7(6):19. doi: 10.1167/tvst.7.6.19

Retina December 2018

Optical Coherence Tomography Angiography in Familial Exudative Vitreoretinopathy: Clinical Features and Phenotype-Genotype Correlation

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Chonglin Chen; Chengxi Liu; Zhirong Wang; Limei Sun; Xiujuan Zhao; Songshan Li; Xiaoling Luo; Aiyuan Zhang; Victor Chong; Lin Lu; Xiaoyan Ding
TAGS: angiogram, phenotype, genotype, signs and symptoms, optical coherence tomography, familial exudative vitreoretinopathy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5726-5734. doi: 10.1167/iovs.18-25377

Retina November 2018

Morphologic, Biomechanical, and Compositional Features of the Internal Limiting Membrane in Pathologic Myopic Foveoschisis

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Lu Chen; Yantao Wei; Xuezhi Zhou; Zhaotian Zhang; Wei Chi; Li Gong; Xintong Jiang; Shaochong Zhang
TAGS: western blotting, astrocytes, collagen, collagen type iv, fluorescent antibody technique, gliosis, tissue membrane, microscopy, atomic force, surgical procedures, operative, body tissue, eye, proteins, mass or substance concentration per volume, pathogenesis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5569-5578. doi: 10.1167/iovs.18-24676

Genetics November 2018

Spectrum of Variants in 389 Chinese Probands With Familial Exudative Vitreoretinopathy

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Jia-Kai Li; Yian Li; Xiang Zhang; Chun-Li Chen; Yu-Qing Rao; Ping Fei; Qi Zhang; Peiquan Zhao; Jing Li
TAGS: cohort studies, genes, proband, chinese people, chinese (other dialects), familial exudative vitreoretinopathy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5368-5381. doi: 10.1167/iovs.17-23541

Includes: Supplemental Content

Retinal Cell Biology October 2018

Altered Decorin Biology in Proliferative Vitreoretinopathy: A Mechanistic and Cohort Study

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Ghazala Begum; Jenna O'Neill; Rishika Chaudhary; Karen Blachford; David R. J. Snead; Martin Berry; Robert A. H. Scott; Ann Logan; Richard J. Blanch
TAGS: cell culture techniques, fibronectins, cohort studies, vitreoretinopathy, proliferative, vitreous body, epithelial to mesenchymal transition, laminin, collagen, fibrosis, enzyme-linked immunosorbent assay, radiation recall dermatitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4929-4936. doi: 10.1167/iovs.18-24299

Includes: Supplemental Content

Review September 2018

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

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Gabriel Velez; Peter H. Tang; Thiago Cabral; Galaxy Y. Cho; Daniel A. Machlab; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: biological markers, health, body tissue, vitreous body, eye, proteins, proteomics, vitreoretinal disease, precision
Trans. Vis. Sci. Tech.. 2018; 7(5):12. doi: 10.1167/tvst.7.5.12

Anatomy and Pathology/Oncology September 2018

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

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Zachary K. Goldsmith; William Coppess; Andrew S. Irvine; Kelley Yuan; Samuel R. Barsh; Madison K. Ritter; Matthew W. McEwen; Jacqueline Flores-Otero; Aileen Garcia-Vargas; Magaly Martinez-Ferrer; Rachel C. Brennan; Vanessa M. Morales-Tirado; Matthew W. Wilson
TAGS: signal transduction, cell culture techniques, western blotting, enzyme-linked immunosorbent assay, blood platelets, cell proliferation, flow cytometry, cell lines, cell survival, platelet-derived growth factor, platelet-derived growth factor receptor, retinoblastoma, rna, messenger, seeds, spheroids, cellular, vitreous body, diagnostic imaging, eye, neoplasms, rna, small interfering, nuclear translocation, proto-oncogene proteins c-akt, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4486-4495. doi: 10.1167/iovs.18-24359

Articles August 2018

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

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Nobuo Machinaga; Gary W. Ashley; Ralph Reid; Atsushi Yamasaki; Kyosuke Tanaka; Koichi Nakamura; Yoshiyuki Yabe; Yasushi Yoshigae; Daniel V. Santi
TAGS: half-life, injections, oryctolagus cuniculus, vitreous body, eye, molecule
Trans. Vis. Sci. Tech.. 2018; 7(4):21. doi: 10.1167/tvst.7.4.21

Includes: Supplemental Content

Retina August 2018

Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging

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Ignacio Melgar-Asensio; Irawati Kandela; Fraser Aird; Soesiawati R. Darjatmoko; Cristobal de los Rios; Christine M. Sorenson; Daniel M. Albert; Nader Sheibani; Jack Henkin
TAGS: arginine, drug clearance, drug delivery systems, peptides, oryctolagus cuniculus, vitreous body, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4071-4081. doi: 10.1167/iovs.18-24087

Retina July 2018

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment

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Lee Kiang; Bing X. Ross; Jingyu Yao; Sumathi Shanmugam; Chris A. Andrews; Sean Hansen; Cagri G. Besirli; David N. Zacks; Steven F. Abcouwer
TAGS: cytokine, microglia, retinal detachment, rna, messenger, vitreous body, mice, retina, inflammatory response
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3767-3778. doi: 10.1167/iovs.18-24489

Includes: Supplemental Content

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Relationship Between Neutralizing Antibodies Against Adeno-Associated Virus in the Vitreous and Serum: Effects on Retinal Gene Therapy

Discovering Mechanisms in the Changing and Diverse Pathology of Retinopathy of Prematurity: The Weisenfeld Award Lecture

Mycoplasma Ocular Infection in Subretinal Graft Transplantation of iPS Cells-Derived Retinal Pigment Epithelial Cells

Biological Characteristics of Subsilicone Oil Fluid and Differences With Other Ocular Humors

1 H NMR Spectroscopy Characterization of Porcine Vitreous Humor in Physiological and Photoreceptor Degeneration Conditions

Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis

Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

Germline Mutations in CTNNB1 Associated With Syndromic FEVR or Norrie Disease

Color and Temporal Frequency Sensitive Eye Growth in Chick

Fluidics of Single and Double Blade Guillotine Vitrectomy Probes in Balanced Salt Solution and Artificial Vitreous

Optical Coherence Tomography Angiography in Familial Exudative Vitreoretinopathy: Clinical Features and Phenotype-Genotype Correlation

Morphologic, Biomechanical, and Compositional Features of the Internal Limiting Membrane in Pathologic Myopic Foveoschisis

Spectrum of Variants in 389 Chinese Probands With Familial Exudative Vitreoretinopathy

Altered Decorin Biology in Proliferative Vitreoretinopathy: A Mechanistic and Cohort Study

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

Targeting the Platelet-Derived Growth Factor-beta Stimulatory Circuitry to Control Retinoblastoma Seeds

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment

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