Vitreous Disorders

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Articles April 2022

Correlation of Complement Activation in Aqueous and Vitreous in Patients With Proliferative Diabetic Retinopathy

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Jesse M. Smith; Nikhil Mandava; Vanessa Tirado-Gonzalez; Rodrigo Garcia-Santisteban; Matthew D. Geiger; Jennifer L. Patnaik; Ashley Frazer-Abel; Anne M. Lynch; Naresh Mandava; V. Michael Holers; Brandie D. Wagner; Idaira Sanchez-Santos; Daniela Meizner; Hugo Quiroz-Mercado; Alan G. Palestine
TAGS: complement system proteins, diabetic retinopathy, proliferative diabetic retinopathy, vitreous body, complement activation
Trans. Vis. Sci. Tech.. 2022; 11(4):13. doi: https://doi.org/10.1167/tvst.11.4.13

Retina April 2022

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

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Jinglin Lu; Li Huang; Limei Sun; Songshan Li; Zhaotian Zhang; Zhaoxin Jiang; Jiaqing Li; Xiaoyan Ding
TAGS: chinese (other dialects), familial exudative vitreoretinopathies, mutation, proband, signs and symptoms, phenotype, chinese people, family
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):7. doi: https://doi.org/10.1167/iovs.63.4.7

Articles March 2022

Human Vitreous Collagen Fragments Dimension As a Function of Vitrectomy Cut Rate

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Tommaso Rossi; Andrea Speciale; Paola Menichini; Alberto Izzotti; Isabella D'Agostino; Carlandrea Trillo; Serena Telani; Giorgio Querzoli; Guido Ripandelli
TAGS: collagen, vitrectomy, vitreous body, proteins
Trans. Vis. Sci. Tech.. 2022; 11(3):29. doi: https://doi.org/10.1167/tvst.11.3.29

Immunology and Microbiology March 2022

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations

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Julian Wolf; Stefaniya Boneva; Dennis-Dominik Rosmus; Hansjürgen Agostini; Günther Schlunck; Peter Wieghofer; Anja Schlecht; Clemens Lange
TAGS: genes, microglia, monocytes, sequence analysis, rna, transcription, genetic, vitreous body, cell separation, body tissue, fluorescence, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):9. doi: https://doi.org/10.1167/iovs.63.3.9

Includes: Supplemental Content

Retina February 2022

Plasma and Vitreous Metabolomics Profiling of Proliferative Diabetic Retinopathy

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Hanying Wang; Shu Li; Chingyi Wang; Yihan Wang; Junwei Fang; Kun Liu
TAGS: diabetic retinopathy, metabolomics, plasma, proliferative diabetic retinopathy, vitreous body, metabolites
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):17. doi: https://doi.org/10.1167/iovs.63.2.17

Includes: Supplemental Content

Immunology and Microbiology February 2022

Study of the Correlation Between Severity of Endophthalmitis and Posterior Vitreous Detachment Using a Rabbit Endophthalmitis Model

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Ryo Baba; Kazuhiko Umazume; Naohito Koike; Hiroshi Goto
TAGS: endophthalmitis, oryctolagus cuniculus, vitreous detachment, histopathology tests, retina, eye, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):6. doi: https://doi.org/10.1167/iovs.63.2.6

Articles January 2022

OCT Assisted Quantification of Vitreous Inflammation in Uveitis

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Xiaoxuan Liu; Aditya U. Kale; Giovanni Ometto; Giovanni Montesano; Alice J. Sitch; Nicholas Capewell; Charlotte Radovanovic; Nicholas Bucknall; Nicholas A. V. Beare; David J. Moore; Pearse A. Keane; David P. Crabb; Alastair K. Denniston
TAGS: corneal opacity, inflammation, uveitis, vitreous body, eye
Trans. Vis. Sci. Tech.. 2022; 11(1):3. doi: https://doi.org/10.1167/tvst.11.1.3

Includes: Supplemental Content

Retina December 2021

Progression Patterns of Myopic Traction Maculopathy in the Fellow Eye After Pars Plana Vitrectomy of the Primary Eye

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Kangjie Kong; Sisi Xu; Yingchao Wang; Yuhe Qi; Qing Chang; Rui Jiang; Chunhui Jiang; Xin Huang; Dekang Gan; Yanqiong Zhang; Ling Chen; Ling Wang; Xiaogang Luo; Yaowu Qin; Haixiang Wu; Min Zhou; Yingqin Ni; Gezhi Xu
TAGS: eye, macular disorders, traction, vitrectomy, pars plana
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):9. doi: https://doi.org/10.1167/iovs.62.15.9

Genetics December 2021

Ocular Features and Mutation Spectrum of Patients With Familial Exudative Vitreoretinopathy

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Tianchang Tao; Ningda Xu; Jiarui Li; Hongyan Li; Jinfeng Qu; Hong Yin; Jianhong Liang; Mingwei Zhao; Xiaoxin Li; Lvzhen Huang
TAGS: familial exudative vitreoretinopathies, genes, mutation, phenotype, genotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):4. doi: https://doi.org/10.1167/iovs.62.15.4

Includes: Supplemental Content

Articles November 2021

A Smart Vitrector Equipped by a Fiber-Based OCT Sensor Mitigates Intentional Attempts at Creating Iatrogenic Retinal Breaks During Vitrectomy in Pigs

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Alexandre Abid; Renaud Duval; Flavio Rezende; Christos Boutopoulos
TAGS: eye, reaction time, retina, retinal perforations, sensor, suidae, surgeons, surgical procedures, operative, vitrectomy, cadaver
Trans. Vis. Sci. Tech.. 2021; 10(13):19. doi: https://doi.org/10.1167/tvst.10.13.19

Includes: Multimedia, Supplemental Content

Anatomy and Pathology/Oncology November 2021

Intravitreal HDAC Inhibitor Belinostat Effectively Eradicates Vitreous Seeds Without Retinal Toxicity In Vivo in a Rabbit Retinoblastoma Model

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Jessica V. Kaczmarek; Carley M. Bogan; Janene M. Pierce; Yuankai K. Tao; Sheau-Chiann Chen; Qi Liu; Xiao Liu; Kelli L. Boyd; M. Wade Calcutt; Thomas M. Bridges; Craig W. Lindsley; Debra L. Friedman; Ann Richmond; Anthony B. Daniels
TAGS: belinostat, oryctolagus cuniculus, vitreous body, retinoblastoma, melphalan, seeds, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):8. doi: https://doi.org/10.1167/iovs.62.14.8

Includes: Supplemental Content

Articles November 2021

Defining a Cutoff for Progression of Macular Holes

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Carmen Baumann; Saskia Hoffmann; Ahmed Almarzooqi; Navid Johannigmann-Malek; Chris P. Lohmann; Stephen B. Kaye
TAGS: macular holes, malignant hyperthermia due to anesthesia, vitreomacular traction syndrome, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2021; 10(13):2. doi: https://doi.org/10.1167/tvst.10.13.2

Anatomy and Pathology/Oncology October 2021

Posterior Vitreous Detachment in Normal Healthy Subjects Younger Than Age Twenty

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Ayumi Hayashi; Yoko Ito; Yuki Takatsudo; Naoto Hara; Peter L. Gehlbach; Keisuke Mori
TAGS: eye, vitreous body, vitreous detachment, diagnostic imaging, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):19. doi: https://doi.org/10.1167/iovs.62.13.19

Retina October 2021

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1 + Macrophage Infiltration

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Iori Wada; Shintaro Nakao; Muneo Yamaguchi; Yoshihiro Kaizu; Mitsuru Arima; Shinichiro Sawa; Koh-Hei Sonoda
TAGS: diabetic retinopathy, lymphangiogenesis, lymphatic vessels, macrophages, mice, protein overexpression, retina, vascular endothelial growth factor a, vascular endothelial growth factor c, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):17. doi: https://doi.org/10.1167/iovs.62.13.17

Includes: Supplemental Content

Clinical Trials October 2021

Dietary Intervention With a Targeted Micronutrient Formulation Reduces the Visual Discomfort Associated With Vitreous Degeneration

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Emmanuel Ankamah; Marina Green-Gomez; Warren Roche; Eugene Ng; Ulrich Welge-Lüßen; Thomas Kaercher; John M. Nolan
TAGS: diet therapy, micronutrients, placebos, questionnaires, science of nutrition, vision, vitreous degeneration, vitreous floaters, vitreous opacities
Trans. Vis. Sci. Tech.. 2021; 10(12):19. doi: https://doi.org/10.1167/tvst.10.12.19

Includes: Supplemental Content

Articles October 2021

Ocular Penetrance and Safety of the Dopaminergic Prodrug Etilevodopa

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Quanqing Gao; Cassie A. Ludwig; Stephen J. Smith; Ira H. Schachar
TAGS: dopamine, eye, prodrugs, safety, penetrance, genetic, eye injuries, penetrating
Trans. Vis. Sci. Tech.. 2021; 10(12):5. doi: https://doi.org/10.1167/tvst.10.12.5

Includes: Supplemental Content

Retina September 2021

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

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Yinting Song; Mengyu Liao; Xiao Zhao; Han Han; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: macrophages, massively-parallel genome sequencing, mucopolysaccharidoses, retinal pigment cell, vitreous body, cell-derived microparticles, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):26. doi: https://doi.org/10.1167/iovs.62.12.26

Includes: Supplemental Content

Visual Neuroscience September 2021

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

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Tian Tian; Leilei Zou; Shu Wang; Rui Liu; Hong Liu
TAGS: 3,4-dihydroxyphenylacetic acid, caviidae, dopamine, vitreous body, cues, blue light, white light, green light
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):20. doi: https://doi.org/10.1167/iovs.62.12.20

Articles September 2021

Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes

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Sheng Chen; Meiwen Tian; Liang Zhang; Chenli Hu; Ke Liu; Bo Qin; Shenwen Liu
TAGS: eye, follow-up, implantation procedure, retinal detachment, vitreous body, silicone oils, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2021; 10(11):8. doi: https://doi.org/10.1167/tvst.10.11.8

Includes: Multimedia, Supplemental Content

Retina August 2021

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

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Cameron Pole; Adrian Au; Eduardo Navajas; K. Bailey Freund; Srinivas Sadda; David Sarraf
TAGS: diagnostic imaging, eye, face, fovea centralis, optical coherence tomography, tissue membrane, vitreous detachment
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):5. doi: https://doi.org/10.1167/iovs.62.10.5

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Correlation of Complement Activation in Aqueous and Vitreous in Patients With Proliferative Diabetic Retinopathy

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

Human Vitreous Collagen Fragments Dimension As a Function of Vitrectomy Cut Rate

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations

Plasma and Vitreous Metabolomics Profiling of Proliferative Diabetic Retinopathy

Study of the Correlation Between Severity of Endophthalmitis and Posterior Vitreous Detachment Using a Rabbit Endophthalmitis Model

OCT Assisted Quantification of Vitreous Inflammation in Uveitis

Progression Patterns of Myopic Traction Maculopathy in the Fellow Eye After Pars Plana Vitrectomy of the Primary Eye

Ocular Features and Mutation Spectrum of Patients With Familial Exudative Vitreoretinopathy

A Smart Vitrector Equipped by a Fiber-Based OCT Sensor Mitigates Intentional Attempts at Creating Iatrogenic Retinal Breaks During Vitrectomy in Pigs

Intravitreal HDAC Inhibitor Belinostat Effectively Eradicates Vitreous Seeds Without Retinal Toxicity In Vivo in a Rabbit Retinoblastoma Model

Defining a Cutoff for Progression of Macular Holes

Posterior Vitreous Detachment in Normal Healthy Subjects Younger Than Age Twenty

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1 + Macrophage Infiltration

Dietary Intervention With a Targeted Micronutrient Formulation Reduces the Visual Discomfort Associated With Vitreous Degeneration

Ocular Penetrance and Safety of the Dopaminergic Prodrug Etilevodopa

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

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